Wasserlab ULTRAMATIC PLUS Intelligent Ultra-Pure Water System

Overview

The Wasserlab ULTRAMATIC PLUS is a fully integrated, intelligent ultra-pure water system engineered for laboratories requiring continuous, on-demand production of Type I ultrapure water compliant with ASTM D1193-20, ISO 3696:1987 Class 1, and CLSI EP21-A standards. It employs a multi-stage purification architecture comprising pre-treatment (activated carbon + dual-stage sediment filtration), reverse osmosis (RO), electrodeionization (EDI), dual-wavelength UV photooxidation (185 nm + 254 nm), and final point-of-use filtration through a 0.22 µm hydrophilic membrane. This configuration ensures consistent removal of ions, organic contaminants, microorganisms, endotoxins, and submicron particles—delivering water suitable for critical applications including HPLC mobile phase preparation, trace elemental analysis (ICP-MS, AAS), cell culture media formulation, and molecular biology workflows (PCR, sequencing, electrophoresis). The system operates under continuous real-time monitoring of key parameters—including resistivity, TOC, temperature, feed pressure, and operational runtime—enabling full traceability and adherence to GLP/GMP documentation requirements.

Key Features

• 4.3-inch high-resolution capacitive touchscreen interface with intuitive icon-driven navigation and multilingual support (English, Spanish, German, French)
• Comprehensive real-time parameter display: resistivity (18.2 MΩ·cm), TOC (<3 ppb), temperature-compensated conductivity, feed water pressure, system uptime, and consumable service timers
• Triple-level alarm system with visual indicators and audible alerts for out-of-specification conditions (e.g., resistivity drop, TOC excursion, low feed pressure, expired consumables)
• Programmable dispensing modes: volume-controlled, time-controlled, and manual activation—each with configurable preset volumes and auto-shutoff
• Integrated temperature compensation (±0.1 °C resolution) ensuring accurate resistivity reporting across ambient operating conditions (10–30 °C)
• Modular consumable design with RFID-tagged cartridges for automatic recognition, usage tracking, and predictive replacement scheduling
• UV lamp lifecycle management with integrated 254 nm germicidal and 185 nm photooxidative lamps—monitored via cumulative irradiation dose counters

Sample Compatibility & Compliance

The ULTRAMATIC PLUS delivers water meeting or exceeding the most stringent international specifications for Type I reagent water. Its output complies with ASTM D1193-20 (Type I), ISO 3696:1987 (Grade 1), and CLSI EP21-A for clinical laboratory use. Endotoxin levels remain below 0.03 EU/mL—validated per USP and EP 2.6.1—making it suitable for parenteral solution preparation and primary cell culture. Bacterial counts are maintained at 0.1 µm) is reduced to non-detectable levels per ISO 8573-1:2010 Class 2. All wetted materials comply with USP Class VI biocompatibility testing and FDA 21 CFR 177.2600 for food-contact polymers. The system supports audit-ready electronic logs required under FDA 21 CFR Part 11 when paired with Wasserlab’s optional SecureLog software module.

Software & Data Management

The embedded firmware supports automated data logging of all critical process variables at user-defined intervals (1 sec to 60 min). Logs are stored internally (≥12 months of continuous data) and exportable via USB to CSV or PDF formats. Optional SecureLog software enables role-based access control, digital signature authentication, and electronic audit trails aligned with ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, Accurate). Historical data can be queried by date range, parameter, or event type (e.g., “resistivity alert”, “cartridge replacement”). All firmware updates are digitally signed and verified prior to installation to ensure integrity and regulatory compliance.

Applications

• HPLC, UHPLC, and LC-MS mobile phase and blank preparation
• ICP-MS, GF-AAS, and ICP-OES calibration standard dilution
• Electrophysiology buffer formulation and patch-clamp solutions
• Monoclonal antibody purification and sterile filtration validation
• Next-generation sequencing library preparation and qPCR master mix dilution
• Pharmaceutical stability testing and dissolution media preparation per USP

FAQ

What standards does the ULTRAMATIC PLUS meet for ultrapure water quality?
It consistently delivers water compliant with ASTM D1193-20 Type I, ISO 3696:1987 Grade 1, and CLSI EP21-A specifications—including resistivity ≥18.2 MΩ·cm, TOC <3 ppb, bacteria <1 CFU/mL, and endotoxin <0.03 EU/mL.
Can the system be integrated into a laboratory information management system (LIMS)?
Yes—via optional RS-232/USB-to-Ethernet gateway and Wasserlab’s API-enabled SecureLog software, enabling bidirectional data exchange with major LIMS platforms using HL7 or ASTM E1384 protocols.
How often must consumables be replaced?
Typical service intervals: RO membrane (36 months), EDI stack (48 months), dual-wavelength UV lamp (12,000 hours), and 0.22 µm terminal filter (6 months or 1,500 L, whichever occurs first)—all tracked automatically by the onboard system.
Is feed water pretreatment required?
Yes—the system requires feed water with conductivity ≤20 µS/cm and pressure between 1–6 bar. A dedicated pre-treatment unit (e.g., activated carbon + softener) is recommended for municipal supplies with high hardness or chlorine residuals.
Does the ULTRAMATIC PLUS support remote monitoring?
With the optional Ethernet/Wi-Fi module and SecureLog Cloud subscription, administrators can monitor system status, receive SMS/email alerts, and review historical logs from any authorized device.