Hettich MIKRO 200 Benchtop High-Speed Centrifuge
| Brand | Hettich |
|---|---|
| Origin | Germany |
| Model | MIKRO 200 |
| Instrument Type | Benchtop Centrifuge |
| Speed Range | Up to 15,000 rpm |
| Max RCF | 21,382 × g |
| Max Capacity | 30 × 1.5/2.0 mL |
| Dimensions (H×W×D) | 260 × 275 × 344 mm |
| Weight | ~11.5 kg |
| Cooling | Ventilated (non-refrigerated) |
| Rotor Types | Fixed-angle rotors (24–30 position), including 24×2.0 mL (40°/45°), 30×2.0 mL (dual-row, 40°/52.5°), 20×2.0 mL cryotube rotor, and 4×0.2 mL PCR strip rotor |
Overview
The Hettich MIKRO 200 is a compact, high-performance benchtop centrifuge engineered for precision separation of biological macromolecules—including nucleic acids, proteins, organelles, and subcellular particles—in research, clinical, and quality control laboratories. Utilizing fixed-angle rotor geometry and optimized aerodynamic design, it delivers consistent sedimentation efficiency across diverse sample volumes (0.2–2.0 mL) while maintaining mechanical stability at sustained speeds up to 15,000 rpm. Its ventilated thermal management system ensures stable operation during extended runs without active refrigeration—ideal for applications where temperature-sensitive denaturation is not a primary concern, such as routine DNA pellet recovery, bacterial cell harvesting, or microfiltration support. Designed and manufactured in Germany under ISO 9001-certified production protocols, the MIKRO 200 complies with IEC 61010-1 safety standards for laboratory electrical equipment and meets CE marking requirements for electromagnetic compatibility (EMC) and low-voltage directive conformity.
Key Features
- Robust brushless DC motor delivering high torque and long service life with minimal maintenance
- Intuitive rotary dial interface with LED display for precise speed (rpm) and time (1 s–99 min) setting
- Automatic rotor identification via mechanical coding—ensures safe operation within certified RCF limits for each installed rotor
- Programmable acceleration/deceleration profiles (soft start/brake) to minimize sample disturbance and tube breakage
- Integrated imbalance detection with automatic shutdown at >5 g asymmetry—enhancing operator safety and instrument longevity
- Compact footprint (260 × 275 × 344 mm) optimized for limited bench space without compromising structural rigidity
- Low-noise operation (<58 dB(A) at maximum speed) suitable for shared lab environments
Sample Compatibility & Compliance
The MIKRO 200 supports standardized microcentrifuge tubes (1.5 mL and 2.0 mL), PCR strips (0.2 mL), and cryovials (up to 2.0 mL), accommodating common consumables from leading global suppliers (e.g., Eppendorf, Sarstedt, Thermo Fisher). All factory-certified rotors—including 24-position (40° and 45°), 30-position dual-row, 20-position cryotube, and 4-position PCR strip variants—are validated per ISO 15189 and CLSI EP05-A3 guidelines for reproducibility and inter-run consistency. The instrument’s non-refrigerated design aligns with workflows requiring ambient-temperature pelleting (e.g., plasmid DNA isolation per Qiagen protocols, protein precipitation using ammonium sulfate), and its RCF performance (up to 21,382 × g) satisfies ASTM D3924-19 criteria for particle sedimentation validation in analytical microbiology and biopharmaceutical QC.
Software & Data Management
While the MIKRO 200 operates via standalone hardware controls, it supports GLP-compliant documentation through external logbook integration. Each run records timestamp, set speed, duration, and rotor ID (mechanically encoded), enabling traceability for audit-ready records. When used in regulated environments (e.g., ISO 13485-certified medical device manufacturing or USP compliant analytical labs), users may pair the centrifuge with LIMS or ELN systems via manual entry or barcode-scanned rotor ID logging. Firmware updates are performed offline via USB port, ensuring data integrity and eliminating network exposure risks—consistent with FDA 21 CFR Part 11 principles for electronic record retention.
Applications
- Routine nucleic acid purification (genomic DNA, plasmid prep, RNA extraction)
- Bacterial and yeast cell pellet collection prior to lysis
- Clarification of crude lysates and supernatant filtration support
- Micro-particle concentration in environmental or food safety testing (e.g., pathogen enrichment)
- Preparative steps in ELISA, Western blot, and flow cytometry sample preparation
- QC release testing of sterile-filtered biologics intermediates
FAQ
Is the MIKRO 200 suitable for use with hazardous or infectious samples?
Yes—when paired with sealed, biocontainment-certified rotors and tubes (e.g., O-ring–sealed 2.0 mL conical tubes), it meets BSL-2 containment requirements per WHO Laboratory Biosafety Manual (4th ed.).
Can the centrifuge be calibrated in-house?
Speed calibration requires traceable tachometer verification against NIST-traceable reference standards; Hettich recommends annual third-party calibration per ISO/IEC 17025.
Does it support variable radius or swing-bucket configurations?
No—the MIKRO 200 is exclusively configured for fixed-angle rotors to maintain compactness and maximize RCF efficiency; swing-bucket capability is available in the MIKRO 220 R model.
What is the warranty coverage?
Standard 24-month parts-and-labor warranty, extendable to 36 months with Hettich CarePlus service contract, including preventive maintenance and priority technical support.
Are rotor certifications included with purchase?
Yes—each rotor ships with individual CE Declaration of Conformity, material test reports (EN 10204 3.1), and maximum speed/RCF certification valid for the specified tube types and fill volumes.
