KNF LIQUIPORT NF1.100 Diaphragm Liquid Transfer Pump

Overview

The KNF LIQUIPORT NF1.100 is a precision-engineered diaphragm liquid transfer pump designed for reliable, pulse-free fluid handling in analytical, laboratory, and process-critical environments. Unlike peristaltic or syringe-based systems, the NF1.100 employs a reciprocating PTFE-coated diaphragm actuated by an electromagnetic or brushless DC motor—delivering consistent volumetric displacement without mechanical compression of tubing. This architecture eliminates pulsation-induced measurement artifacts common in peristaltic pumps, ensures long-term chemical compatibility across aggressive solvents and reagents, and supports dry-run operation without damage—a critical advantage in intermittent or low-flow applications such as reagent dosing, system priming, or closed-loop circulation. Manufactured in Germany to ISO 9001-certified processes, the NF1.100 integrates robust sealing geometry, corrosion-resistant wetted materials, and thermally stable motor design to sustain performance under continuous duty cycles at ambient temperatures from 5 °C to 40 °C and fluid temperatures up to 80 °C.

Key Features

• Pulse-free, positive-displacement flow with ±2% volumetric accuracy across the full 0.2–3 L/min operating range
• Self-priming capability up to 3 mWg, enabling reliable startup from elevated or remote reservoirs
• Chemical resistance validated for strong acids (e.g., HNO₃, H₂SO₄), bases (e.g., NaOH), halogenated solvents, and oxidizing agents via configurable wetted-path materials: PP (KT), PVDF (TT), or PTFE (FT) pump heads; PTFE-coated diaphragms; and FFKM (perfluoroelastomer) valves
• IP65-rated enclosure for dust-tight and low-pressure water-jet protection—suitable for benchtop use in regulated QC labs or semi-industrial settings
• Analog 0–10 V control interface (RC variants) supporting external PLCs or DAQ systems for programmable flow ramping, setpoint tracking, and integration into ASTM E2500-compliant validation protocols
• Compact footprint (130 × 90 × 177 mm) and lightweight construction (1.5 kg) facilitate modular integration into automated analyzers, wash stations, or microfluidic platforms without structural reinforcement

Sample Compatibility & Compliance

The NF1.100 accommodates aqueous, organic, and mixed-phase liquids with viscosities up to 150 cSt—covering typical applications involving buffers, standards, cleaning solutions, and calibration fluids. Its dry-run capability mitigates risk during system startup, empty-tank conditions, or flow interruption events, aligning with IEC 61000-6-2 EMC immunity requirements and supporting GLP/GMP workflows where unattended operation must maintain traceability. All material configurations comply with USP Class VI biocompatibility testing for KT/TT/FT variants, and FFKM valve elastomers meet FDA 21 CFR 177.2600 for repeated food-contact exposure. The pump is CE-marked and conforms to RoHS 2011/65/EU, EN 61000-3-2 (harmonic current emissions), and EN 61326-1 (electrical equipment for measurement, control, and laboratory use).

Software & Data Management

While the NF1.100 operates as a standalone analog-controlled device, its RC-series models provide real-time status feedback—including TTL logic signals for run/fault indication and serial error codes (e.g., overtemperature, stall detection)—enabling integration into LabVIEW, Python-based control frameworks, or SCADA architectures. When deployed in automated liquid handling systems, the pump’s linear 0–10 V input allows precise correlation between control voltage and flow output, supporting audit-ready data logging when paired with compliant DAQ hardware. For facilities requiring 21 CFR Part 11 compliance, KNF provides optional documentation packages—including Factory Acceptance Test (FAT) reports, material traceability certificates, and IQ/OQ templates—to support qualification under GxP-regulated environments.

Applications

• Automated sample introduction and carrier fluid delivery in HPLC, IC, and flow-injection analysis (FIA) systems
• Reagent metering and wash solution circulation in ELISA, PCR, and immunoassay platforms
• Continuous recirculation in electrochemical cells, corrosion test rigs, or membrane filtration modules
• Low-pulsation fluid supply for optical sensors, spectrophotometric flow cells, and microreactors where pressure stability affects signal integrity
• Backup or primary pumping in environmental monitoring stations requiring long-term field reliability and minimal maintenance intervention

FAQ

Can the NF1.100 handle abrasive slurries or particulate-laden fluids?
No—the pump is engineered for clean, low-viscosity liquids. Suspended solids exceeding 50 µm or abrasive particles may compromise diaphragm seal life and valve seating integrity.
Is the 0–10 V analog control bidirectional or only proportional to flow rate?
It is unidirectional: 0 V = minimum flow (typically ~0.2 L/min), 10 V = maximum rated flow (e.g., 3 L/min for NF1.300). No reverse flow capability is provided.
Does KNF offer validation support for pharmaceutical manufacturing use?
Yes—KNF supplies IQ/OQ documentation kits, material compliance dossiers, and calibration guidance aligned with Annex 15 and ASTM E2500, facilitating integration into FDA- or EMA-inspected facilities.
What is the expected service life under continuous operation?
With proper fluid compatibility and ambient conditions, the NF1.100 achieves >20,000 hours MTBF (mean time between failures) based on accelerated life testing per ISO 13849-1.
Are replacement diaphragms and valves available as field-serviceable components?
Yes—genuine KNF spare parts (e.g., diaphragm kit 100-001, FFKM valve set 100-003) are stocked globally and require no specialized tools for replacement, typically completed in <15 minutes without disassembling the motor assembly.