Pribolab® EQ-MPS 1000 Automated Magnetic Bead-Based Sample Preparation System
| Brand | Pribolab |
|---|---|
| Origin | Shandong, China |
| Manufacturer Type | Authorized Distributor |
| Country of Origin | China |
| Model | EQ-MPS 1000 |
| Pricing | Available Upon Request |
Overview
The Pribolab® EQ-MPS 1000 Automated Magnetic Bead-Based Sample Preparation System is an integrated, benchtop workstation engineered for high-precision, reproducible isolation and concentration of target analytes—particularly mycotoxins—from complex biological and botanical matrices. Utilizing magnetic bead separation technology grounded in surface-functionalized solid-phase extraction (SPE), the system operates on the principle of affinity-driven binding between ligand-modified superparamagnetic beads and target molecules under controlled buffer conditions. This enables selective capture, washing, and elution in a fully automated sequence without manual column packing, centrifugation, or solvent evaporation. Designed specifically for laboratories performing routine regulatory testing (e.g., EU Commission Regulation (EC) No. 1881/2006, China GB 2761-2023), the EQ-MPS 1000 bridges the gap between manual immunoaffinity column workflows and high-throughput liquid handling platforms—delivering robustness, traceability, and reduced inter-operator variability.
Key Features
- Automated magnetic bead handling with precise 3D motion control for uniform bead suspension, binding, washing, and elution across up to 12 samples per run.
- Pre-programmed, protocol-driven operation via intuitive touchscreen interface; supports one-touch execution of standardized methods including AOAC Official Method 2019.04 and ISO/IEC 17025-compliant workflows.
- Dedicated magnetic bead cartridges and reagent kits—pre-validated for mycotoxin classes including aflatoxins (B1, B2, G1, G2), ochratoxin A, zearalenone, deoxynivalenol (DON), T-2/HT-2 toxins, and fumonisins—ensuring batch-to-batch consistency and minimal cross-reactivity.
- Integrated thermal management for temperature-sensitive steps (e.g., antibody-antigen binding at 25–37 °C); optional ambient or refrigerated reagent storage compartment (4–10 °C).
- Modular deck layout compatible with standard 96-well plates, deep-well plates (1.2 mL), and custom vial formats (12 × 15 mm); accommodates downstream coupling to HPLC, UHPLC, LC-MS/MS, and ELISA readers.
Sample Compatibility & Compliance
The EQ-MPS 1000 is validated for use with cereals (corn, wheat, barley), feedstuffs, spices (paprika, black pepper), traditional Chinese medicinal herbs (e.g., ginseng, astragalus, licorice), infant formula, and dietary supplements. All magnetic bead kits are manufactured under ISO 9001-certified processes and undergo rigorous lot-release testing for binding capacity (>95% recovery), non-specific adsorption (<5% matrix interference), and stability (≥12 months at 4 °C). The system supports audit-ready documentation: each run generates a timestamped log file containing operator ID, protocol version, sample IDs, step durations, temperature profiles, and error flags—fully compliant with GLP and FDA 21 CFR Part 11 requirements when paired with Pribolab’s LIMS-integrated software module.
Software & Data Management
Controlled by Pribolab’s MPS Control Suite v3.2 (Windows-based), the system provides role-based user access (Administrator, Technician, Auditor), electronic signature capability, and automatic backup of method files and run records to network drives or NAS devices. Raw data export is supported in CSV, PDF, and XML formats—including full audit trails with WHO-recognized ALCOA+ attributes (Attributable, Legible, Contemporaneous, Original, Accurate, Complete, Consistent, Enduring, Available). Optional integration with Thermo Fisher Chromeleon, Waters Empower, or Agilent OpenLab enables direct injection scheduling and result correlation.
Applications
- Routine quantification of regulated mycotoxins in food safety laboratories accredited to ISO/IEC 17025.
- High-volume screening of herbal raw materials and finished TCM products for quality control and pharmacopoeial compliance (ChP, USP, EP).
- Method development and validation studies requiring orthogonal sample cleanup prior to mass spectrometry analysis.
- Support for multi-analyte panels in clinical research settings where fungal metabolite profiling is required (e.g., biomonitoring of aflatoxin-albumin adducts).
- Training and education platforms in university analytical chemistry and food science programs due to its visual workflow transparency and low skill-barrier operation.
FAQ
What types of mycotoxins can be extracted using the EQ-MPS 1000?
The system supports over 15 regulated mycotoxins across six structural families, with validated kits available for aflatoxins, ochratoxin A, zearalenone, trichothecenes, fumonisins, and patulin.
Is method validation support provided with the instrument?
Yes—Pribolab supplies full validation packages including spike recovery data (n = 6 replicates across three concentration levels), precision (RSD ≤8%), linearity (R² ≥0.999), and matrix-matched calibration curves for major commodity groups.
Can the system be integrated into an existing LIMS environment?
Absolutely—the MPS Control Suite features HL7 and ASTM E1384-compliant APIs and supports direct bidirectional communication with major LIMS vendors including LabVantage, STARLIMS, and Thermo Fisher SampleManager.
What maintenance is required for long-term operational reliability?
Routine maintenance includes monthly calibration of magnetic field strength and pipetting accuracy, biannual inspection of fluidic seals and motor encoders, and annual performance verification using NIST-traceable reference standards.
Are reagent kits supplied sterile and endotoxin-free?
All magnetic bead suspensions and wash/elution buffers are filter-sterilized (0.22 µm PVDF) and tested for endotoxin levels <0.5 EU/mL per USP , suitable for sensitive immunoassay applications.
