Chu Ding Technology LGJ-12 Benchtop Freeze Dryer
| Brand | Chu Ding Technology |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Authorized Distributor |
| Country of Origin | China |
| Model | LGJ-12 |
| Price | USD 4,450 (approx.) |
| Cold Trap Temperature | ≤ −55 °C (−80 °C optional) |
| Ultimate Vacuum | < 10 Pa |
| Freeze-Drying Area | 0.07–0.1 m² |
| Water Capture Capacity | 3 kg/24 h |
| Load Volume (Bulk) | 0.7–1.2 L |
| Dimensions (W×D×H) | 565 × 420 × 700 mm |
| Tray Configuration | 4 stainless steel trays (Ø200 mm) for bulk loading |
| Vial Configuration | 3 trays (Ø180 mm) with manual vacuum-sealable lid compression |
| Max Vial Capacity | 135 × Ø22 mm vials or 8 multi-port flasks (100–1000 mL) |
| Optional Features | Nitrogen purge valve, rotary pre-freezing attachment |
Overview
The Chu Ding Technology LGJ-12 Benchtop Freeze Dryer is a compact, laboratory-scale lyophilization system engineered for reproducible primary and secondary drying of heat-sensitive biologicals, pharmaceuticals, diagnostics, and research-grade samples. Operating on the fundamental principles of sublimation under deep vacuum and controlled thermal input, the LGJ-12 removes water from frozen samples by transitioning ice directly to vapor—bypassing the liquid phase—thereby preserving structural integrity, enzymatic activity, and long-term stability. Designed for benchtop deployment in QC labs, academic research facilities, and early-stage formulation development, it supports both batch processing of bulk material and parallel lyophilization of multiple vials or flasks via its multi-port manifold configuration. Its integrated pre-freezing capability eliminates dependency on external ultra-low temperature freezers, enabling full-cycle lyophilization—from freezing through primary drying to final desiccation—within a single instrument footprint.
Key Features
- Stainless steel cold trap chamber (≥ Ø200 mm opening) with no internal coil obstruction—optimized for rapid ice condensation and simplified cleaning
- High-efficiency dual-stage compressor refrigeration system (imported), achieving ≤ −55 °C cold trap temperature (−80 °C variant available upon request)
- Full-color LCD interface with Chinese-language menu navigation and real-time graphical display of chamber pressure, cold trap temperature, and shelf/tray temperature profiles
- Dual-mode operation: bulk tray drying (4 adjustable-height Ø200 mm stainless steel trays) and multi-flask lyophilization (8-port manifold with interchangeable 100–1000 mL flask support)
- Manual vacuum-sealable lid compression mechanism for stoppering vials under inert atmosphere (optional nitrogen purge valve compatible)
- Integrated pre-cooling rack doubling as a conduction-enhancing “flow guide” to accelerate sublimation front propagation during primary drying
- Transparent polycarbonate bell jar chamber with safety interlock—enabling visual process monitoring without vacuum break
- Corrosion-resistant 304 stainless steel construction for cold trap, sample platform, and control panel surfaces
Sample Compatibility & Compliance
The LGJ-12 accommodates diverse sample formats including aqueous protein solutions, microbial cultures, tissue homogenates, polymer dispersions, and diagnostic reagents. Its design aligns with foundational requirements of ISO 22000, ISO 13485, and USP for sterile product processing validation. While not certified for GMP manufacturing, the system supports GLP-compliant documentation workflows when paired with external audit-ready data loggers. The absence of internal condenser coils minimizes cross-contamination risk between batches—a critical consideration for multi-user academic and contract research environments. All wetted parts comply with FDA 21 CFR Part 11 traceability prerequisites when connected to validated third-party software platforms.
Software & Data Management
The embedded controller logs time-stamped pressure, temperature, and vacuum status at user-defined intervals (1–60 second resolution). Raw datasets export via USB to CSV format for post-processing in MATLAB, Python (Pandas), or commercial CFD/lyo-modelling tools. Though no proprietary PC software is bundled, the system’s RS-232/USB interface enables integration with LabArchives ELN, DeltaV DCS, or custom SCADA architectures using Modbus RTU protocol. Audit trails—including operator ID, parameter changes, and cycle start/stop events—are retained onboard for ≥30 days, supporting basic 21 CFR Part 11 compliance when combined with institutional identity management policies.
Applications
- Stabilization of monoclonal antibodies, vaccines, and plasmid DNA prior to long-term storage
- Routine dehydration of bacterial and fungal cultures for strain banking
- Preparation of calibration standards for mass spectrometry and elemental analysis
- Lyophilization of nanocarrier suspensions (liposomes, polymeric micelles) without aggregation
- Processing of botanical extracts and nutraceutical formulations requiring low-thermal-degradation protocols
- Method development for scalable freeze-drying cycles prior to pilot-plant transfer
FAQ
What is the maximum allowable sample volume per cycle?
For bulk tray loading: 0.7–1.2 L across four Ø200 mm trays (depth ≤10 mm). For vial-based drying: up to 135 × Ø22 mm vials (900 mL total) or 8 large flasks (max 1000 mL each).
Can the LGJ-12 be used for terminal sterilization?
No—it is not designed for depyrogenation or sterility assurance; it is intended for stabilization of already-sterile or non-sterile research materials.
Is remote monitoring supported?
Yes, via optional RS-232-to-Ethernet gateway and third-party SCADA integration; no native Wi-Fi or cloud connectivity is built-in.
What maintenance intervals are recommended?
Compressor oil inspection every 12 months; cold trap cleaning after every 10 cycles or visible ice buildup; vacuum pump oil replacement every 500 operating hours.
Does the system meet CE or UL safety certification?
It carries CCC (China Compulsory Certification); CE marking is available upon request for EU shipment with additional conformity assessment documentation.
