Organomation MULTIVAP Series Nitrogen Evaporator
| Brand | Organomation |
|---|---|
| Origin | USA |
| Model | MULTIVAP Series |
| Heating Method | Water Bath |
| Temperature Range | Up to 99 °C |
| Temperature Stability | ±0.5 °C |
| Sample Tube Diameter | 10–22 mm |
| Gas Flow Rate | 0–30 L/min |
| Sample Positions | 100 |
| Heating Power | 1100 W |
Overview
The Organomation MULTIVAP Series Nitrogen Evaporator is an engineered solution for controlled, parallel solvent removal in analytical sample preparation workflows. It operates on the principle of gentle inert-gas displacement—introducing a stream of nitrogen (or compressed air) across the surface of heated liquid samples to accelerate evaporation while minimizing thermal degradation, oxidation, or cross-contamination. Designed for compatibility with HPLC, GC, GC-MS, LC-MS, and ELISA workflows, the system delivers reproducible concentration of volatile and semi-volatile analytes from biological fluids, environmental extracts, pharmaceutical formulations, and food matrices. Its modular architecture supports both water bath and dry block configurations, with standardized gas distribution manifolds and precision-adjustable needle valves enabling independent flow control per row—a critical capability for heterogeneous sample sets requiring differential evaporation kinetics.
Key Features
- Modular platform available in six standard configurations: 9-, 30-, 48-, 64-, 80-, and 100-position formats—each optimized for footprint efficiency and ergonomic access within fume hoods.
- Water bath heating system (1100 W) ensures uniform thermal distribution across all sample positions; temperature is digitally regulated with ±0.5 °C stability over the full 0–99 °C range.
- Gas manifold with individually calibrated needle valves allows per-row flow adjustment (0–30 L/min total), supporting method-specific optimization for diverse solvent boiling points and sample volumes.
- Stainless steel (14-gauge or 19-gauge) evaporator needles—4 inches in length—are chemically resistant and compatible with common organic solvents including acetonitrile, methanol, ethyl acetate, and hexane.
- Corrosion-resistant construction includes laboratory-grade polymers and optional acid-resistant coating for applications involving hydrochloric, nitric, or sulfuric acid digestates.
- Removable sample tray assembly simplifies high-throughput loading/unloading; spring-assisted lift mechanism reduces operator fatigue during vertical positioning.
- Dual safety systems: high-limit thermal cutoff switch (dry block models) and GFCI-certified power input (UL/CSA compliant).
Sample Compatibility & Compliance
The MULTIVAP Series accommodates tubes, vials, centrifuge tubes, and conical flasks with diameters ranging from 10 to 22 mm and capacities up to 50 mL. Its design conforms to widely adopted laboratory safety and quality standards, including ANSI Z9.5 (laboratory ventilation), UL 61010-1 (electrical safety), and IEC 61326-1 (EMC for measurement equipment). While not inherently 21 CFR Part 11-compliant as a standalone instrument, it integrates seamlessly into validated workflows when paired with LIMS or electronic lab notebook (ELN) systems that enforce audit trails, user authentication, and data integrity protocols required under GLP and GMP environments.
Software & Data Management
The MULTIVAP Series operates as a hardware-controlled analog system without embedded firmware or touchscreen interface. All parameter adjustments—including bath temperature and gas flow—are performed manually via calibrated dials and mechanical valves. This architecture eliminates software validation overhead and enhances long-term reliability in regulated laboratories where deterministic operation and minimal failure modes are prioritized. For traceable documentation, users may log setpoints and run conditions in paper-based or digital batch records aligned with ISO/IEC 17025 or FDA guidance for non-automated instrumentation.
Applications
- Residue analysis in environmental testing (e.g., pesticide extraction from soil/water per EPA Methods 508, 8081, 8270).
- Drug metabolite isolation in clinical pharmacokinetics and bioequivalence studies (ICH M10).
- Fatty acid methyl ester (FAME) concentration prior to GC-FID analysis in food lipid profiling.
- Nucleic acid cleanup following phenol-chloroform extraction in molecular biology workflows.
- Heavy metal preconcentration from digested biological tissues prior to ICP-MS quantification.
- Standard preparation for calibration curves in regulated QC/QA labs performing USP , EP 2.2.46, or JP 2.07 assays.
FAQ
What gas pressure is required for optimal performance?
A supply pressure of 30–150 psig is recommended at the inlet; the internal regulator delivers 0–30 psig to the manifold, ensuring stable flow even under variable demand.
Can the MULTIVAP be used with air instead of nitrogen?
Yes—though nitrogen is preferred for oxygen-sensitive analytes, compressed air is acceptable for robust compounds and routine QC applications.
Is the water bath removable for cleaning?
Yes, the stainless steel bath vessel is fully detachable and designed for easy descaling and decontamination between batches.
Does Organomation offer validation support documents?
Factory test reports, material certifications (e.g., RoHS, REACH), and dimensional drawings are provided; IQ/OQ protocols can be developed in collaboration with qualified third-party service providers.
How is tube height variability accommodated?
Each needle is mounted on a vertically adjustable carriage with lockable stops, allowing precise alignment to meniscus level across tubes of differing heights (1–50 mL volume range).
