Organomation N-EVAP-34 Water-Bath Nitrogen Evaporator

Overview

The Organomation N-EVAP-34 is a precision-engineered water-bath nitrogen evaporator designed for reproducible, low-temperature solvent removal in analytical sample preparation workflows. It operates on the principle of gentle inert-gas displacement—introducing a controlled stream of nitrogen (or compressed air) over the surface of heated liquid samples to accelerate evaporation while minimizing thermal degradation and analyte loss. Unlike dry-block or infrared-based concentrators, the N-EVAP-34 utilizes a circulating water bath to deliver uniform, stable thermal energy across all 34 sample positions, ensuring high inter- and intra-run consistency. This architecture is particularly critical for thermally labile compounds encountered in environmental analysis, pharmaceutical QC, clinical toxicology, and food safety testing—where deviations in temperature or gas flow can compromise recovery, accuracy, or method validation outcomes.

Key Features

• 34-position rotating and vertically adjustable circular sample manifold enables ergonomic front-access operation within standard fume hoods—reducing user fatigue and improving workflow efficiency.
• Independent stainless-steel needles (4″ × 19 gauge), each fitted with a precision needle valve and calibrated flow meter, allow per-channel gas flow optimization from 0–330 mL/min—critical for heterogeneous sample matrices or mixed tube geometries.
• Water-bath heating system delivers ±2 °C temperature stability across the full range (ambient to 99 °C), with typical ramp time of ~45 minutes from 20 °C to 60 °C—ensuring predictable kinetics without overshoot or localized boiling.
• Chemically resistant construction: All wetted and structural components are fabricated from laboratory-grade stainless steel and anodized aluminum; optional acid-resistant coating available for applications involving HCl, HF, or strong oxidizers.
• Programmable timer with auto-shutoff and delayed-start functionality supports unattended overnight concentration—fully compatible with ISO/IEC 17025 and FDA 21 CFR Part 11–aligned lab practices when integrated with validated LIMS or ELN systems.

Sample Compatibility & Compliance

The N-EVAP-34 accommodates tubes, vials, centrifuge tubes, and conical flasks with outer diameters from 10 mm to 30 mm and nominal liquid volumes between 1 mL and 50 mL. Its open-frame design allows direct integration with common autosampler vial racks and custom adapters. The instrument meets essential electrical safety standards (UL 61010-1, CSA C22.2 No. 61010-1) and is engineered to support regulatory-compliant sample preparation under GLP, GMP, and ISO 17025 frameworks. While not itself a regulated device, its repeatable thermal and pneumatic performance—documented via calibration certificates traceable to NIST standards—enables laboratories to satisfy audit requirements for method robustness and equipment qualification (IQ/OQ/PQ).

Software & Data Management

The N-EVAP-34 is a stand-alone analog-controlled instrument with no embedded firmware or digital interface. Temperature setpoint and individual gas flow rates are adjusted manually via mechanical dials and calibrated rotameters. This design prioritizes operational simplicity, long-term reliability, and immunity to software obsolescence—making it ideal for high-volume QC labs where uptime and technician training efficiency are paramount. For laboratories requiring electronic recordkeeping, external data loggers (e.g., Omega OM-DAQPRO-5300) may be connected to PT100 probe outputs (optional accessory) to capture time-stamped temperature profiles compliant with 21 CFR Part 11 Annex 11 audit trails when paired with validated software.

Applications

• Pre-concentration of aqueous and organic extracts prior to GC, GC-MS, LC, or LC-MS/MS analysis—especially for pesticides, PAHs, PCBs, and mycotoxins.
• Residue analysis in food, soil, and water matrices per EPA Methods 505, 525.3, 8081B, and ASTM D7066.
• Pharmaceutical impurity profiling and stability-indicating assays requiring strict control over evaporation kinetics.
• Clinical toxicology workflows involving urine, plasma, and whole blood specimens—where analyte volatility and matrix interference demand precise thermal management.
• Forensic drug chemistry sample cleanup prior to derivatization or instrumental analysis.

FAQ

What is the maximum recommended operating temperature for aqueous versus organic solvent applications?
For aqueous buffers and saline solutions, the bath may be operated up to 99 °C. When using volatile organics (e.g., hexane, ethyl acetate, dichloromethane), we recommend limiting bath temperature to ≤45 °C to prevent excessive vapor pressure buildup and ensure safe, controlled evaporation.
Can the N-EVAP-34 be used with compressed air instead of nitrogen?
Yes—though nitrogen is preferred for oxidation-sensitive analytes (e.g., unsaturated lipids, catecholamines), compressed air may be substituted where cost or infrastructure constraints exist; note that ambient moisture and oxygen content must be considered during method validation.
Is calibration documentation provided with the instrument?
Each unit ships with a factory calibration certificate for temperature accuracy (±2 °C at 60 °C) and gas flow linearity (±5% of full scale); NIST-traceable recalibration services are available through Organomation-authorized service centers.
How often should the stainless-steel needles be replaced?
Under normal use with clean solvents, needles require replacement only after visible corrosion, bending, or clogging—typically every 12–24 months; spare needles (P/N NEVAP-NEEDLE) are stocked globally.
Does the N-EVAP-34 support multi-level rack configurations for varying tube heights?
No—the rotating sample holder is fixed-height; however, optional height-adjustable tube supports (P/N NEVAP-ADJ-SPACER) accommodate tubes ranging from 50 mm to 150 mm in length while maintaining optimal gas-jet alignment.