Labonce Labonce-400BI Biochemical Incubator
| Brand | Labonce |
|---|---|
| Model | Labonce-400BI |
| Temperature Range | 0–60°C |
| Internal Volume | 400 L |
| Internal Dimensions (W×D×H) | 600×700×950 mm |
| External Dimensions (W×D×H) | 780×1060×1750 mm |
| Power Consumption | 1.0 kW |
| Standard Shelving | 3 adjustable stainless steel shelves (max. 10 supported) |
| Temperature Uniformity | ≤2.0°C at 37°C |
| Temperature Fluctuation | ±0.5°C (high-temp range), ±1.0°C (low-temp range) |
| Ambient Operating Temperature | +5 to +35°C |
| Power Supply | AC 220 V ±10%, 50 Hz |
| Construction | Exterior – powder-coated steel |
| Optional Accessories | UV germicidal lamp, SMS alert module, relative humidity display, touch-screen controller (BIT model) with 3-tier user permissions and 21 CFR Part 11-compliant audit trail |
Overview
The Labonce Labonce-400BI Biochemical Incubator is a precision-engineered environmental chamber designed for stable, reproducible temperature-controlled cultivation of biological samples in research, quality control, and regulatory-compliant laboratory environments. It operates on the principle of forced-air convection with an optimized dual-channel air circulation system—engineered to minimize thermal gradients across the entire working volume. Unlike passive or natural-convection incubators, the Labonce-400BI employs a variable-speed axial fan and symmetrically distributed air ducts to ensure uniform heat distribution, meeting the stringent spatial uniformity requirements defined in GB/T 28851–2012, the national standard for biochemical incubators in China. Its operational temperature range spans 0°C to 60°C, making it suitable for mesophilic microbial growth, enzyme activity assays, BOD testing, pharmaceutical stability studies, and long-term cell culture preparation where precise thermal constancy—not humidity control—is the primary parameter.
Key Features
- Robust thermal architecture: Mirror-polished AISI 304 stainless-steel interior eliminates corrosion, particulate shedding, and organic residue retention—critical for GLP-compliant sample integrity and ease of decontamination.
- High-efficiency refrigeration: Hermetically sealed industrial-grade compressor delivers consistent cooling performance across ambient conditions from +5°C to +35°C, with low acoustic emission (<52 dB(A)) and extended service life under continuous operation.
- Intelligent climate management: LCD-based controller enables real-time monitoring and adjustment of temperature setpoint, fan speed, and alarm thresholds; fan speed modulation optimizes airflow without inducing desiccation or mechanical stress on sensitive cultures.
- Dual-layer safety redundancy: Independent mechanical overtemperature limiter (non-software-dependent) works in parallel with electronic thermal cutoff; compressor protection circuitry guards against thermal overload and refrigerant pressure anomalies.
- Traceable data handling: Integrated thermal printer provides immediate hard-copy logging of time-stamped temperature readings; internal flash memory retains ≥30 days of 1-minute interval data; USB port supports secure export to external drives for archival or audit review.
- Ergonomic design: Full-view double-glazed inner door minimizes radiant heat loss during observation; castor-mounted chassis allows safe repositioning within lab workflows; integrated LED illumination enhances visual inspection without thermal interference.
Sample Compatibility & Compliance
The Labonce-400BI accommodates standard microbiological and biochemical sample formats—including Petri dishes, test tubes, flasks, multi-well plates, and serum bottles—within its 400 L chamber. Its 600 × 700 × 950 mm internal cavity permits vertical stacking of up to ten stainless-steel shelves (three supplied as standard), with load capacity rated at 15 kg per shelf. The unit complies with GB/T 28851–2012 for thermal performance, electromagnetic compatibility (GB/T 18268.1), and electrical safety (GB 4793.1). When equipped with the optional BIT touchscreen controller, it supports configurable user roles (Administrator/Operator/Viewer), immutable audit logs, electronic signatures, and exportable CSV reports—enabling alignment with FDA 21 CFR Part 11, ISO/IEC 17025, and EU GMP Annex 11 documentation requirements.
Software & Data Management
Data acquisition and reporting are handled via embedded firmware supporting timestamped logging at user-selectable intervals (1–60 minutes). All recorded values—including setpoint, actual chamber temperature, fan status, and alarm events—are stored with millisecond-level time resolution. The USB export function writes encrypted, tamper-evident files compatible with common laboratory information management systems (LIMS) and statistical process control (SPC) platforms. No cloud connectivity or remote access is implemented by default—ensuring full data sovereignty. For advanced validation scenarios, the BIT controller option adds role-based authentication, session timeouts, and cryptographic hash verification of exported datasets.
Applications
- Environmental microbiology: BOD5 determination per ISO 5815–1, coliform enumeration per ISO 9308–1, and activated sludge respiration rate assays.
- Pharmaceutical QC: Stability testing of raw materials and finished products under ICH Q1A(R2) intermediate storage conditions (e.g., 30°C ±2°C/65% RH ±5%—when paired with external humidification).
- Clinical diagnostics: Culture incubation for aerobic/facultative pathogens per CLSI M02–A12; mycobacterial growth support at 35–37°C.
- Agricultural biotechnology: Seed germination trials, fungal isolate propagation, and pesticide degradation kinetics studies.
- Academic research: Long-duration enzyme kinetics, recombinant protein expression pre-incubation, and anaerobic culture starter preparation (when used with gas-tight accessories).
FAQ
What is the maximum permissible ambient temperature for continuous operation?
The Labonce-400BI is rated for uninterrupted use in ambient environments between +5°C and +35°C. Operation above +35°C may impair compressor efficiency and compromise temperature uniformity.
Can this incubator maintain humidity?
No—the Labonce-400BI is a dry-air, temperature-only incubator. Humidity control requires external humidification modules or integration with standalone RH generators.
Is the internal data logger compliant with 21 CFR Part 11?
The base model’s internal memory and printer do not provide electronic signature or audit-trail functionality. Full Part 11 compliance is achieved only with the optional BIT controller upgrade.
How often does the UV sterilization option require lamp replacement?
When installed, the 254 nm UV-C lamp has a rated service life of 8,000 hours; annual verification of irradiance output using a calibrated radiometer is recommended for validated applications.
Are calibration certificates available?
NIST-traceable factory calibration reports (including temperature uniformity and fluctuation verification at 37°C and 55°C) can be supplied upon request—subject to additional lead time and fee.
