Hesiyi HR26M Floor-standing High-speed Refrigerated Centrifuge

Overview

The Hesiyi HR26M is a floor-standing high-speed refrigerated centrifuge engineered for demanding laboratory separation tasks requiring both high g-force performance and precise thermal control. It operates on the principle of sedimentation under centrifugal acceleration—generating up to 58,695 ×g at 25,000 rpm—to resolve heterogeneous mixtures including cell suspensions, subcellular organelles, macromolecular complexes, and particulate contaminants in biopharmaceutical, clinical diagnostics, and academic research settings. Its robust architecture integrates a high-torque AC frequency-controlled motor, imported non-CFC refrigeration system (R404a), and a fully sealed stainless-steel centrifuge chamber—ensuring stable rotational dynamics, reproducible temperature maintenance during runs, and long-term mechanical integrity under continuous operation.

Key Features

• High-precision temperature control from −20 °C to +40 °C with ±1 °C accuracy; real-time setpoint adjustment during operation and pre-cooling functionality for rapid chamber equilibration
• 10-step programmable acceleration and deceleration profiles to minimize sample disturbance and prevent resuspension of pellets
• Triple-stage damping system combining mechanical counterbalance, silicone-based vibration isolation, and reinforced steel chassis for operational stability and noise reduction (≤65 dB(A))
• CE-certified Weintek touchscreen HMI compliant with NEMA 4 ingress protection and IEC 61131-2 safety standards; multilingual interface (English, Chinese) supporting GLP-aligned parameter logging
• Biocontainment-compliant angular rotors with integrated silicone O-rings meeting RoHS 2015/863 requirements to suppress aerosol leakage during high-speed spins
• Mechanical door interlock with auto-engagement mechanism—no solenoid dependency—ensuring fail-safe lid sealing across variable ambient conditions
• 16 user-programmable protocols with full traceability: real-time display of speed ramp curves, cumulative centrifugation time (k-factor integration), and chamber temperature history

Sample Compatibility & Compliance

The HR26M accommodates a broad range of primary sample containers via optional aviation-grade aluminum angular rotors and polyamide fiber adapters—supporting tubes and bottles from 1.5 mL microcentrifuge tubes up to 1000 mL industrial bottles. All rotor configurations undergo static and dynamic balancing per ISO 15883-5 Annex B and are validated for cyclic fatigue resistance at maximum rated speeds. The instrument complies with ISO 9001:2015 (quality management) and ISO 13485:2016 (medical device QMS), and carries CFDA registration for use in regulated clinical laboratories in China. While not FDA 510(k)-cleared, its design adheres to general safety principles referenced in IEC 61010-2-020 (particular requirements for centrifuges) and supports audit-ready documentation for GLP/GMP environments through timestamped parameter export.

Software & Data Management

Control firmware enables local storage of all run metadata—including rotor ID, speed profile, temperature log, and fault events—with timestamped CSV export via USB port. No cloud connectivity or proprietary software installation is required; data files are human-readable and compatible with standard LIMS import workflows. Audit trails include operator ID (if configured via external authentication), start/stop timestamps, deviation alerts (e.g., overspeed, imbalance detection), and thermal excursion logs. The system meets foundational data integrity expectations aligned with ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, Accurate, Complete, Consistent, Enduring, Available) for routine QC/QA applications where electronic records are retained for ≥2 years.

Applications

• Preparative isolation of mammalian cells, bacteria, and yeast from culture media
• Clarification of crude lysates prior to chromatography or electrophoresis
• Separation of plasma lipoprotein fractions (HDL, LDL, VLDL) in clinical lipidomics
• Concentration of viral vectors and exosomes for downstream characterization
• Routine quality control of raw materials in pharmaceutical manufacturing (e.g., particulate matter testing per USP )
• Environmental microbiology: sedimentation of waterborne pathogens for enumeration and identification

FAQ

Does the HR26M support rotor auto-recognition?

No. Rotor identification is manual via operator input during protocol setup; users must select the correct rotor type and maximum speed limit before initiating a run.

Is remote monitoring or network connectivity available?

The HR26M does not feature Ethernet, Wi-Fi, or RS-232 interfaces. All operation and data retrieval occur locally via the front-panel touchscreen and USB export.

What refrigerant is used, and is it compliant with global environmental regulations?

R404a is employed—a hydrofluorocarbon blend with zero ozone depletion potential (ODP = 0) and classified as acceptable under current EU F-Gas Regulation (EU) No 517/2014 for laboratory equipment with annual charge <10 kg.

Can the unit maintain temperature during extended idle periods?

Yes. Standby cooling mode actively regulates chamber temperature within ±1 °C of setpoint while powered on but not spinning, minimizing thermal drift between sequential runs.

Are third-party rotors or adapters supported?

Only Hesiyi-certified rotors and adapters are validated for safety and performance. Use of non-OEM components voids warranty and violates CE conformity declarations.