Hanuo TYZD-I Microplate Vibrator

Overview

The Hanuo TYZD-I Microplate Vibrator is an engineered orbital shaker designed specifically for high-throughput microplate handling in life science laboratories. It operates on the principle of controlled orbital motion—generating uniform, low-shear agitation ideal for cell suspension, ELISA plate washing, immunoassay incubation, and reagent mixing. Unlike conventional rocking or linear shakers, its precise 6 mm amplitude and fixed 1500 rpm oscillation frequency ensure reproducible kinetic energy transfer across all wells of standard 96-well, 384-well, or deep-well microplates—without splashing or cross-contamination. The device features a compact footprint (220 × 180 × 130 mm), making it suitable for benchtop use in biosafety cabinets, cold rooms, or shared core facilities where spatial efficiency is critical.

Key Features

• Brushless DC motor sourced from international suppliers—ensures maintenance-free operation, silent performance (<45 dB(A)), and long-term rotational stability under continuous duty cycles.
• Silicone-coated vibration platform with non-slip surface—securely holds single or stacked microplates (up to 3 plates simultaneously), minimizing lateral displacement during operation.
• Precise digital timer with 1-minute resolution—supports programmable run durations from 0 to 120 minutes or indefinite continuous mode, enabling unattended overnight assays.
• Fixed-frequency orbital drive at 1500 rpm—optimized for consistent mixing kinetics across diverse liquid volumes (50 µL–300 µL per well) without vortex formation or meniscus disruption.
• Robust ABS housing with reinforced base—designed for vibration damping and mechanical stability on standard lab benches; no leveling feet required.
• Universal AC input (220 V ±10%, 50 Hz)—compliant with IEC 61000-4 electromagnetic compatibility standards for laboratory environments.

Sample Compatibility & Compliance

The TYZD-I accommodates ANSI/SLAS-standard microplates (SBS format), including flat-bottom, U-bottom, V-bottom, and PCR plates. Its silicone tray conforms to ISO 10993-5 biocompatibility requirements for non-cytotoxic contact surfaces. While the unit lacks integrated temperature control, its ambient-temperature operation aligns with ASTM E2795–11 guidelines for non-thermal microplate agitation validation. It is routinely deployed in GLP-compliant labs for pre-analytical sample homogenization prior to spectrophotometric, fluorometric, or luminescence readouts—fully traceable via manual log entries or external time-stamped documentation systems.

Software & Data Management

As a standalone analog-digital hybrid instrument, the TYZD-I does not incorporate embedded firmware, network connectivity, or proprietary software. All operational parameters are set manually via front-panel controls, ensuring deterministic behavior and eliminating cybersecurity vulnerabilities associated with IoT-enabled lab devices. For audit-trail compliance (e.g., FDA 21 CFR Part 11), users may integrate the vibrator into validated workflows using external electronic lab notebooks (ELNs) or LIMS platforms that record start/stop timestamps, operator ID, and protocol versioning. No calibration certificate is shipped by default; however, periodic verification of timer accuracy and rotational consistency can be performed using Class II stopwatch and optical tachometer per ISO/IEC 17025 internal verification protocols.

Applications

• ELISA and multiplex immunoassay plate washing and substrate incubation
• Cell-based assay preparation—including suspension of adherent cells post-trypsinization
• Antibody-antigen binding enhancement during kinetic binding studies
• Homogenization of lysates in 96-well format prior to centrifugation or filtration
• Pre-analytical mixing of standards, controls, and samples in clinical diagnostics workflows
• Supporting automated liquid handlers by pre-equilibrating reagents at ambient conditions

FAQ

Is the TYZD-I compatible with 384-well microplates?
Yes—the silicone tray provides sufficient grip and dimensional tolerance to stabilize standard SBS-format 384-well plates without adapter accessories.
Does this unit meet CE or RoHS certification requirements?
The device complies with RoHS Directive 2011/65/EU for hazardous substance restrictions; CE marking is not applicable as it falls outside the scope of EU Machinery Directive 2006/42/EC due to lack of moving guards or high-energy mechanisms.
Can multiple TYZD-I units be synchronized for parallel processing?
No synchronization interface is provided; however, identical timer settings across units yield statistically equivalent agitation profiles when operated under identical environmental conditions.
What maintenance is required for long-term reliability?
No scheduled maintenance is necessary beyond periodic cleaning of the silicone tray with 70% ethanol and visual inspection of motor housing integrity every 6 months.
Is there a calibration service available from Hanuo?
Hanuo offers factory recalibration for timer and speed verification upon return shipment; calibration certificates follow ISO/IEC 17025 reporting conventions and include measurement uncertainty budgets.