Hanuo FD1A50 Benchtop Freeze Dryer
| Brand | Hanuo |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Authorized Distributor |
| Product Category | Domestic |
| Model | FD1A50 |
| Instrument Type | Standard Shelf-Type Freeze Dryer |
| Application Scope | Laboratory Use |
| Freeze-Drying Area | 0.12 m² |
| Ultimate Vacuum | < 20 Pa |
| Condenser Temperature | −50 °C |
| Water Capture Capacity | 3 kg/24 h |
| Dimensions (W×D×H) | 380 × 600 × 345 mm |
| Power Supply | 220 V, 50 Hz, 850 W |
| Sample Tray Configuration | Φ200 mm × 4 layers |
| Maximum Load Volume | 1.2 L |
Overview
The Hanuo FD1A50 is a compact, benchtop shelf-type freeze dryer engineered for reliable primary drying of thermolabile biological and pharmaceutical samples in research laboratories and quality control environments. It operates on the principle of lyophilization—sublimation of ice under deep vacuum and low-temperature conditions—enabling preservation of structural integrity, bioactivity, and chemical stability in sensitive materials such as proteins, vaccines, monoclonal antibodies, enzymes, and microbial cultures. Unlike conventional air-drying or spray-drying methods, lyophilization minimizes thermal degradation, oxidation, and denaturation by removing water directly from the frozen state. The FD1A50 integrates a −50 °C condenser, a robust refrigeration system, and a high-efficiency vacuum chamber capable of sustaining pressures below 20 Pa—sufficient to support stable ice sublimation across standard laboratory sample formats.
Key Features
- Benchtop footprint (380 × 600 × 345 mm) optimized for limited lab space without compromising performance
- Shelf-type design with four stainless-steel sample trays (Φ200 mm each), enabling uniform heat transfer and scalable batch processing
- −50 °C dual-stage condenser with 3 kg/24 h water capture capacity, ensuring consistent vacuum integrity during extended drying cycles
- Integrated vacuum system includes a 2 L oil-sealed rotary vane pump (supplied), pre-configured for rapid evacuation and stable low-pressure operation
- Intuitive manual control interface with real-time vacuum readout and temperature monitoring at the condenser stage
- Compliance-ready architecture: designed to support GLP documentation workflows and traceable process parameters when paired with external data loggers
Sample Compatibility & Compliance
The FD1A50 accommodates aqueous solutions, suspensions, and gels in standard glass vials or open trays up to 1.2 L total volume per cycle. Its 0.12 m² drying area supports typical R&D-scale batches—ideal for formulation development, stability testing, and small-batch production of biologics. While not certified to ISO 22000 or FDA 21 CFR Part 11 out-of-the-box, the system’s mechanical reproducibility and stable vacuum/temperature profiles align with foundational requirements for method validation per ICH Q5C and USP <1211>. Users may implement additional controls—including calibrated pressure transducers, independent temperature mapping, and audit-trail-capable logging—to meet GMP-aligned qualification protocols.
Software & Data Management
The FD1A50 operates via a dedicated analog/digital hybrid control panel with vacuum gauge display and condenser temperature indicator. It does not include embedded PC-based software or Ethernet connectivity. However, its electrical and vacuum interfaces are compatible with third-party data acquisition systems (e.g., LabVIEW, WinCC, or custom Python-based SCADA setups) for time-stamped recording of vacuum level, condenser temperature, and runtime. For regulated environments, users are advised to pair the unit with validated external loggers that provide electronic signatures, user access controls, and 21 CFR Part 11–compliant audit trails.
Applications
- Stabilization of heat-sensitive biopharmaceuticals including recombinant proteins, viral vectors, and live-attenuated vaccines
- Preparation of reference standards and calibration materials for analytical chemistry and clinical diagnostics
- Drying of bacterial and fungal cultures for long-term cryopreservation and strain banking
- Processing of natural extracts, botanicals, and functional food ingredients while retaining volatile compounds and antioxidant activity
- Supporting material science studies involving porous matrix formation, pore structure analysis (via SEM post-drying), and reconstitution kinetics evaluation
FAQ
What is the maximum sample volume supported per cycle?
The FD1A50 accommodates up to 1.2 liters of liquid sample distributed across four Φ200 mm trays, assuming standard freezing depth and uniform ice layer formation.
Is the vacuum pump included in the standard configuration?
Yes—the system ships with a 2 L domestic oil-sealed rotary vane vacuum pump, pre-connected and tested for immediate operation.
Can this unit be used for sterile processing?
No. The FD1A50 is not equipped with HEPA filtration, steam-in-place (SIP), or cleanroom-rated construction; it is intended for non-aseptic R&D use only.
Does the condenser require regular defrosting?
Yes. Manual defrosting is required after each full 24-hour water capture cycle or when ice accumulation exceeds 80% of condenser capacity to maintain vacuum efficiency.
What maintenance intervals are recommended?
Vacuum pump oil should be replaced every 200 operating hours; refrigerant levels and seal integrity should be verified annually by qualified service personnel.
