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PerkinElmer QSight-Specific Infinity 1046 Nitrogen & Dry Air Generator by PEAK

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Brand PEAK
Origin United Kingdom
Manufacturer Type Original Equipment Manufacturer (OEM)
Import Status Imported
Model INFINITY 1046
Nitrogen Generation Principle Membrane Separation
Nitrogen Output Flow 20 L/min
Dry Air Output Flow 70 L/min
Output Pressure 110 psi (758 kPa)
Nitrogen Purity Up to 99.5%
Nitrogen Dew Point −40 °C

Overview

The PerkinElmer QSight-Specific Infinity 1046 Nitrogen & Dry Air Generator is an engineered solution designed exclusively to support the gas supply requirements of the PerkinElmer QSight™ triple quadrupole liquid chromatography–mass spectrometry (LC-MS/MS) system. Unlike generic nitrogen generators, the Infinity 1046 integrates seamlessly with QSight’s dual-gas architecture—delivering precisely regulated, high-purity nitrogen for ion source nebulization and collision-induced dissociation (CID), alongside instrument-grade dry air for auxiliary pneumatic functions such as autosampler actuation and valve sequencing. Its membrane-based separation technology leverages selective permeation of atmospheric gases across hollow-fiber polymeric membranes to extract nitrogen from compressed air feedstock, eliminating the need for cryogenic or pressure swing adsorption (PSA) infrastructure. This design ensures stable, continuous output without consumables, moving parts, or periodic regeneration cycles—making it ideal for unattended 24/7 operation in regulated analytical laboratories.

Key Features

  • QSight-optimized dual-output configuration: independent, pressure-stabilized nitrogen (20 L/min @ 110 psi) and dry air (70 L/min @ 110 psi) streams, each equipped with dedicated pressure regulators and particulate/moisture filtration
  • Membrane separation core with integrated coalescing pre-filtration and desiccant post-drying, achieving consistent ≤99.5% N₂ purity and −40 °C dew point under nominal load conditions
  • No rotating components or solenoid valves—acoustic noise level <35 dBA at 1 m distance, suitable for open-plan lab environments
  • Modular footprint (W × D × H: 480 × 520 × 720 mm) with castor-mounted chassis for flexible placement and easy integration into existing LC-MS utility zones
  • Compressed air feed compatibility: accepts clean, oil-free, dried air at 100–120 psi from either lab central supply or optional PEAK-compatible scroll-type air compressors (e.g., Genius系列)
  • Factory-calibrated pressure transducers and flow sensors traceable to UKAS-accredited standards; full 12-month on-site warranty inclusive of preventive maintenance visit

Sample Compatibility & Compliance

The Infinity 1046 is validated for use with all PerkinElmer QSight models (QSight 200, 210, 220, 400, 410, 420) and complies with the gas quality specifications outlined in PerkinElmer Application Note AN-LCMS-005. Its output meets ISO 8573-1:2010 Class 2:2:2 for particulate, water, and oil content—ensuring compatibility with sensitive electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) sources. The generator supports GLP and GMP workflows through optional audit-trail-enabled firmware (v3.2+), which logs operational parameters—including inlet pressure, outlet flow rates, runtime hours, and alarm events—in accordance with FDA 21 CFR Part 11 data integrity requirements when paired with PEAK’s PEAKLink™ software.

Software & Data Management

While the Infinity 1046 operates autonomously via analog pressure/flow control, optional digital integration is available via RS-485 Modbus RTU interface. PEAKLink™ v4.1 software enables remote monitoring of real-time status indicators (e.g., membrane health index, filter saturation alerts), scheduled calibration reminders, and export of CSV-formatted operational logs for internal QA review. All firmware updates are delivered via secure HTTPS portal and validated against IEC 62443-3-3 cybersecurity guidelines. No cloud dependency: local database storage ensures compliance with data sovereignty policies in EU, APAC, and North American regulatory jurisdictions.

Applications

  • Routine quantitative bioanalysis (e.g., pharmacokinetic studies per FDA Guidance for Industry)
  • Environmental contaminant screening (EPA Method 1694, 533) requiring stable ESI response over extended batch runs
  • Food safety testing (AOAC 2012.01, EN 15662) where nitrogen purity directly impacts MRM transition reproducibility
  • Clinical toxicology labs operating under CAP/CLIA accreditation—where documented gas source traceability is mandatory
  • Core facility environments supporting multi-user QSight access, where shared gas infrastructure must guarantee uninterrupted uptime

FAQ

Is an external air compressor required?
Yes—the Infinity 1046 requires a clean, oil-free, dried compressed air supply at 100–120 psi. Lab central air systems meeting ISO 8573-1 Class 1:2:1 are acceptable; otherwise, PEAK recommends pairing with its Genius 1020 or 1030 series oil-free compressors.
Can the generator be used with non-QSight instruments?
It is not recommended. The pressure setpoints, flow profiles, and electrical interlocks are calibrated specifically for QSight hardware interfaces and firmware handshake protocols.
What maintenance intervals apply beyond the 12-month warranty?
Annual replacement of the coalescing pre-filter (PEAK P/N: FIL-1046-C) and desiccant cartridge (P/N: DES-1046-D) is advised; membrane stack service life exceeds 15,000 operating hours under specified inlet air quality.
Does the unit comply with electrical safety standards for global deployment?
Yes—it carries CE marking per EN 61010-1:2010, UKCA certification, and UL 61010-1 recognition for use in the USA and Canada.

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