HUXI MD200-2 Dry Block Nitrogen Evaporator

Overview

The HUXI MD200-2 Dry Block Nitrogen Evaporator is an engineered solution for parallel solvent removal and sample concentration in analytical laboratories. It operates on the principle of inert gas-assisted evaporation—introducing a controlled stream of nitrogen directly above heated liquid surfaces to accelerate solvent volatilization while minimizing oxidation, thermal degradation, or cross-contamination. Unlike water-bath evaporators, the MD200-2 employs a precisely regulated dry block heating system, eliminating risks associated with water ingress, bath contamination, or inconsistent thermal transfer. Its design supports reproducible, low-oxygen concentration workflows essential for sensitive analytes in pharmaceutical development, clinical toxicology, environmental residue analysis, and metabolomics sample preparation.

Key Features

• Dual independent dry block modules—each accommodating one standardized 12-position rack (16.5 mm well diameter)—enabling simultaneous processing of up to 24 samples with uniform thermal distribution.
• Programmable 5-stage LCD interface supporting time-based ramping, hold steps, and automatic shutdown; timer range spans 1 minute to 100 hours with 0.1°C resolution and real-time countdown display.
• Individual gas needle control via 24 dedicated on/off valves—preventing unnecessary nitrogen consumption during partial-load operation and improving cost-efficiency in high-throughput labs.
• Adjustable gas manifold height and needle positioning—compatible with varying tube geometries (e.g., culture tubes, GC vials, centrifuge tubes); standard needle length is 150 mm, optimized for vertical alignment over sample meniscus.
• Integrated safety architecture: dual-limit over-temperature cutoff, continuous thermal monitoring, audible fault alert, and automatic system halt upon sensor anomaly or power fluctuation.
• Compact footprint (330 × 220 × 540 mm) and ventilated chassis design allow safe integration into fume hoods when handling volatile or hazardous solvents (e.g., chloroform, hexane, ethyl acetate).

Sample Compatibility & Compliance

The MD200-2 accommodates standard laboratory consumables including 12 × 16.5 mm test tubes, 1.5 mL and 2.0 mL microcentrifuge tubes, and custom-configured racks (optional modules: HX05–HX22 series). All contact surfaces are constructed from corrosion-resistant anodized aluminum and stainless steel—compatible with common organic solvents and aqueous buffers. While not certified to ISO/IEC 17025 or FDA 21 CFR Part 11 out-of-the-box, the instrument’s deterministic timing, traceable temperature calibration points, and audit-ready operational logs support GLP/GMP-aligned documentation when integrated with validated lab procedures. Users may perform internal verification per ASTM D129 or USP guidelines for evaporation efficiency and recovery consistency.

Software & Data Management

The MD200-2 operates via embedded firmware without external PC dependency. All process parameters—including setpoint temperature, elapsed time, remaining time, and current block temperature—are continuously displayed on a backlit LCD panel. The 5-segment programmable timer allows users to define multi-step protocols (e.g., initial gentle drying at 40°C for 30 min, followed by accelerated evaporation at 80°C for 90 min). Though no proprietary software or USB export is included, the device supports manual log recording for QA/QC traceability. For regulated environments, laboratories may integrate its usage into electronic lab notebooks (ELNs) or LIMS platforms using timestamped operator entries and photo documentation of module configuration.

Applications

• Routine sample cleanup prior to LC-MS/MS, GC-MS, or HPLC analysis—especially in bioanalytical method validation where recovery rate and matrix effect mitigation are critical.
• High-throughput drug metabolism studies requiring parallel concentration of plasma, urine, or tissue homogenates.
• Pesticide residue testing in food and agricultural commodities per EPA Method 1694 or EN 15662 protocols.
• Environmental analysis of PAHs, PCBs, and organochlorine compounds in soil and water extracts.
• Preparative chemistry workflows involving solvent exchange or reaction quenching under inert atmosphere.

FAQ

What is the maximum recommended operating temperature for long-term stability?
The MD200-2 is rated for continuous operation up to 150°C; however, for optimal heater longevity and consistent temperature uniformity across the block surface, sustained use above 120°C is discouraged unless required by specific method validation.
Can this unit be used with gases other than nitrogen?
Yes—while nitrogen is preferred for its inertness, compressed air or argon may be substituted depending on analyte sensitivity; users must verify compatibility with downstream instrumentation and ensure gas purity meets ISO 8573-1 Class 2 requirements.
Is calibration certificate included with shipment?
No factory-issued calibration certificate is supplied; however, the unit features two calibrated PT100 sensors (one per block), and users may perform in-house verification using NIST-traceable reference thermometers per SOP-defined intervals.
How is gas flow accuracy ensured across all 24 channels?
Each channel incorporates a precision orifice and individual shut-off valve; actual flow distribution depends on upstream regulator stability and line pressure—users should install a calibrated mass flow meter upstream if quantitative gas delivery validation is required.
Does the MD200-2 meet CE or UL safety standards?
The device complies with IEC 61010-1:2010 for electrical safety in laboratory equipment; CE marking is applied for EU market compliance, and full technical documentation is available upon request for regulatory review.