Boxun BXP-130S Biochemical Incubator
| Brand | Boxun |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Direct Manufacturer |
| Region of Origin | Domestic (China) |
| Model | BXP-130S |
| Temperature Range | RT+5°C to 100°C |
| Chamber Dimensions (L×W×H) | 570×400×570 mm |
| External Dimensions (L×W×H) | 735×665×755 mm |
| Temperature Uniformity (at 60°C) | ±0.5°C |
| Temperature Fluctuation (at 60°C) | ±0.3°C |
| Heating Time to 60°C | 20 min |
| 30-Second Recovery Time (after door opening at 60°C) | 13 min |
| Rated Power | 0.55 kW |
| Standard Shelves | 2 pcs |
| Max. Shelves Capacity | 7 pcs |
| PID Control | Yes |
| Programmable Stages | 30 segments × 99 cycles |
| Data Storage Capacity | 4 million entries |
| Interface Ports | 2 × RS-485, 1 × USB |
| Optional Accessories | Thermal Printer (domestic or Epson imported), FDA/GMP Compliance Software, GPRS SMS Alarm Module, Wireless Temperature Validation Probes (≤130°C), HEPA Air Filter (Class 100) |
Overview
The Boxun BXP-130S Biochemical Incubator is a precision-engineered, microprocessor-controlled environmental chamber designed for stable, uniform, and programmable temperature regulation in life science laboratories. It operates on a forced-air convection principle with rear-mounted heating elements and multi-stage fan-assisted airflow management, enabling rapid thermal response and high spatial homogeneity across the 130 L working chamber. Engineered for biochemical applications—including microbial growth, enzyme activity assays, cell culture maintenance (non-CO₂), and stability testing—the BXP-130S delivers reliable thermal performance from ambient +5°C up to 100°C. Its architecture integrates dual independent overtemperature protection circuits (sensor-based PID cutoff and mechanical thermal cutout), ensuring compliance with IEC 61010-1 safety requirements for laboratory equipment. The incubator meets foundational design criteria for GLP-compliant environments and serves as a validated platform for routine QC procedures where traceable temperature control is essential.
Key Features
- 5-inch high-resolution capacitive touchscreen interface with real-time display of setpoint/actual temperature, timer status, fan speed level, air damper position, operational mode, and system alerts.
- Rear-heating configuration with direct airflow injection into the chamber—reducing thermal lag and achieving ≤20 minutes ramp time to 60°C.
- Patented perforated baffle design and 10-step adjustable exhaust damper ensure consistent air exchange rates and minimize vertical/horizontal temperature gradients (±0.5°C uniformity at 60°C).
- Advanced PID algorithm with adaptive tuning supports programmable ramp/soak profiles: up to 30 segments per cycle, 99 cycles total, including controlled heating and cooling rates.
- Dual-layer security: screen lock with customizable password and hardware-level parameter protection to prevent unauthorized modification during GLP/GMP workflows.
- Integrated data logging system stores up to 4 million timestamped temperature records with full export capability via USB—compatible with CSV and Excel formats for audit-ready reporting.
- Comprehensive alarm architecture: visual/audible alerts for overtemperature, sensor failure, door ajar, power interruption, and communication timeout—with optional GPRS SMS notification to preconfigured mobile numbers.
- Standard dual RS-485 ports enable daisy-chain integration into centralized lab monitoring networks; USB port supports firmware updates and local data retrieval.
Sample Compatibility & Compliance
The BXP-130S accommodates standard microbiological and biochemical sample formats, including Petri dishes (up to 150 mm), test tubes (13–25 mm OD), flasks (Erlenmeyer and baffled), and multi-well plates (6–96-well). Its Class 100 HEPA-filtered air option (optional) ensures particulate-free internal atmosphere, suitable for low-bioburden applications such as media preparation, sterility testing support, and reference standard storage. While not certified for ISO 14644-1 cleanroom use as a standalone unit, the filtered configuration aligns with Annex 1 supplementary requirements for background environment control. The incubator’s temperature validation protocol supports calibration traceability to NIST-traceable references, and optional wireless temperature probes (validated at 0°C, 60°C, and 121°C) facilitate IQ/OQ documentation per ASTM E2876 and ISO 17025 guidelines.
Software & Data Management
Data integrity is maintained through built-in non-volatile memory and time-stamped logging with automatic overwrite protection. Exported datasets include absolute timestamps, temperature values, alarm flags, and user-defined event markers. Optional FDA-compliant software provides 21 CFR Part 11–aligned features: electronic signatures, role-based access control, immutable audit trails, and change history tracking for all parameter modifications. GMP version adds batch record linkage, deviation logging, and report generation templates aligned with EU Annex 11 expectations. All software modules operate independently of Windows OS dependencies and support TLS-encrypted remote access when deployed with compatible network gateways.
Applications
- Microbial enumeration and growth kinetics studies (e.g., E. coli, S. aureus, P. aeruginosa) under standardized ISO 4833-1 or USP <61> conditions.
- Enzyme assay incubation requiring precise thermal ramping (e.g., polymerase activation, protease digestion).
- Stability testing of pharmaceutical excipients and diagnostic reagents per ICH Q1A(R2) guidance.
- Environmental simulation for accelerated aging of biopolymer films and hydrogels.
- Support incubation for MALDI-TOF target plate drying and ELISA plate coating steps.
- Reference material conditioning prior to pH, conductivity, or osmolality measurement.
FAQ
Does the BXP-130S support temperature mapping validation?
Yes—when equipped with optional wireless temperature sensors (rated to 130°C), the unit enables 3D thermal mapping per ISO 14159 and ASTM E2876. Sensor data is synchronized and visualized via included analysis software.
Can the incubator be integrated into a LIMS or SCADA system?
Yes—via Modbus RTU over RS-485, the BXP-130S provides read/write access to real-time temperature, alarm status, program stage, and system uptime. Custom OPC UA drivers are available upon request.
Is the HEPA filtration system certified to ISO 14644-1 Class 5?
No—the internal HEPA filter achieves ≥99.99% efficiency at 0.3 µm and maintains Class 100 (ISO 5 equivalent) air cleanliness *within the chamber* under static conditions; however, it is not rated as a full cleanroom-grade air handling unit.
What is the warranty coverage and service support structure?
Boxun provides a 24-month limited warranty covering parts and labor. Field service engineers in North America and EU regions support installation verification, preventive maintenance, and IQ/OQ execution upon request.
Are calibration certificates provided with optional wireless probes?
Yes—NIST-traceable calibration certificates (3-point: 0°C, 60°C, 121°C) are included with each validated probe set, compliant with ISO/IEC 17025 requirements for accredited calibration laboratories.
