Hanon T960 Advanced Automatic Potentiometric Titrator

Overview

The Hanon T960 Advanced Automatic Potentiometric Titrator is an ISO/IEC 17025-aligned electrochemical platform engineered for precision, reproducibility, and regulatory compliance in modern quality control and R&D laboratories. It operates on the fundamental principle of potentiometric endpoint detection—measuring the potential difference (in mV) between a working electrode and a reference electrode as titrant is incrementally delivered, enabling quantitative determination of analyte concentration via stoichiometric reaction equivalence. Designed for universal applicability, the T960 supports classical titration modes including acid-base, redox, argentometric (silver nitrate), and complexometric (EDTA) titrations—each executed with programmable dosing logic, real-time potential monitoring, and thermometric compensation. Its architecture integrates safety-critical engineering: fully enclosed, internally mounted burettes eliminate open reagent handling, minimizing exposure risk and contamination while enabling unattended operation over extended assay sequences.

Key Features

• Modular Multi-Channel Dosing System: Four independent, synchronized dosing units operate simultaneously out-of-the-box; system scalability supports up to six channels via hot-swappable modules—no mechanical disassembly required. Each channel accommodates interchangeable burettes (5 mL, 10 mL, or 25 mL), optimized for volumetric accuracy across low-volume micro-titrations and high-capacity routine assays.
• Integrated Burette Design: Burettes are fully housed within the instrument chassis, accessible only via sealed optical viewing windows. This design complies with IEC 61010-1 safety standards for laboratory equipment and eliminates splash, drip, or overflow hazards during operation, significantly reducing operator exposure to corrosive or toxic reagents.
• High-Fidelity Electrochemical Measurement: Dual-range mV measurement (±2000.0 mV) with 0.1 mV resolution and accuracy; pH measurement from −20.000 to +20.000 pH at 0.001 pH resolution and ±0.003 pH accuracy; integrated PT1000 temperature sensing (0–100 °C, ±0.1 °C) enables automatic temperature compensation per ASTM E2070 and ISO 9001 traceable protocols.
• Intelligent Endpoint Recognition: Supports six standardized titration modes—MEAS (pH/mV/T monitoring), CAL (multi-point pH calibration), SET (fixed-endpoint), MET (equivalent-volume), DET (dynamic derivative-based endpoint), and DOS (predefined volume delivery)—all configurable with user-defined thresholds, delay times, and stirring profiles.
• Automated Post-Titration Protocol: Integrated rinse-and-purge cycle activates automatically after each titration, using dedicated solvent lines to flush electrodes, tubing, and burette tips—ensuring carryover-free analysis and long-term electrode stability.

Sample Compatibility & Compliance

The T960 is validated for aqueous and mixed-solvent matrices commonly encountered in pharmaceutical QC (USP <771>), food safety testing (AOAC 984.27), water quality analysis (EPA 300.0), and industrial chemical certification (ASTM D974, D664). Its electrode interface supports standard glass pH electrodes, silver/silver chloride reference electrodes, platinum redox electrodes, and ion-selective electrodes (ISEs) with BNC or DIN connectors. The system meets GLP/GMP data integrity requirements through built-in audit trail logging (user actions, method changes, calibration events), electronic signature support, and time-stamped raw data export compliant with FDA 21 CFR Part 11 when paired with validated cloud or local LIMS integration.

Software & Data Management

The T960 operates under Hanon’s proprietary TitraSoft™ v4.x software suite, deployed on Windows-based PCs via Ethernet or USB. Software features include drag-and-drop method builder, real-time titration curve visualization with first- and second-derivative overlays, customizable report templates (PDF/CSV/XLSX), and automated pass/fail evaluation against specification limits. Its cloud service layer—HanonCloud™—provides secure, encrypted, role-based access to centralized method libraries, cross-site result comparison dashboards, and version-controlled SOP deployment. All cloud interactions adhere to TLS 1.2+ encryption, GDPR-compliant data residency options, and ISO 27001-certified infrastructure. Audit logs capture every data upload, download, edit, and deletion event—enabling full forensic traceability for internal audits or regulatory inspections.

Applications

• Pharmaceutical: Assay of active pharmaceutical ingredients (APIs), residual acid/base quantification in excipients, Karl Fischer water content validation (via coulometric extension).
• Food & Beverage: Total acidity (TA) in wines and juices, chloride in dairy products, peroxide value in edible oils, free fatty acids in fats.
• Environmental: Alkalinity and hardness in wastewater, cyanide in effluents (pyridine-barbituric acid method), fluoride by ISE titration.
• Chemical Manufacturing: Saponification value of surfactants, amine number in epoxy resins, acid number in lubricants (ASTM D974).
• Academic Research: Kinetic titration studies, equilibrium constant determination, multi-step titration modeling with simultaneous equilibria.

FAQ

Does the T960 support GLP-compliant electronic signatures and audit trails?
Yes. When operated with TitraSoft™ in networked mode and configured with user authentication, all method edits, calibration records, and result approvals generate time-stamped, immutable entries with operator ID and reason-for-change fields—fully satisfying FDA 21 CFR Part 11 and EU Annex 11 requirements.
Can the T960 be integrated into an existing LIMS or ELN environment?
Yes. Native support for ASTM E1384, HL7, and CSV-based batch export enables bidirectional integration with major LIMS platforms (e.g., LabWare, STARLIMS, Thermo SampleManager) via secure API or SFTP protocols.
What maintenance is required for long-term reliability?
Routine maintenance includes monthly electrode calibration verification, quarterly burette seal inspection, and annual gravimetric accuracy check per ISO 8655-6. No consumable parts require replacement outside of standard electrode membranes and tubing—typical service interval exceeds 18 months under normal use.
Is remote troubleshooting supported?
Yes. With customer consent and secure VPN tunneling, Hanon technical support can initiate remote desktop sessions to diagnose firmware issues, validate method configurations, or verify communication stack integrity—minimizing instrument downtime.
How does the cloud service ensure data sovereignty and confidentiality?
HanonCloud™ offers private tenant deployment options, regional data hosting (EU/US/Asia), AES-256 encryption at rest and in transit, and granular permission controls—including method-level visibility restrictions and export-disabled read-only accounts for auditors or QA reviewers.