Titan MPM-2 Dual-Plate Microplate Shaker

Overview

The Titan MPM-2 Dual-Plate Microplate Shaker is an engineered orbital shaker designed specifically for consistent, low-shear mixing of microplates (96-well, 384-well, and compatible deep-well formats) in life science laboratories. It operates on the principle of circular orbital motion—generating uniform horizontal displacement with a fixed 4 mm orbit diameter—to ensure homogenous suspension of cells, reagents, or assay components without foaming or cross-well splashing. Unlike vortex mixers or linear shakers, the MPM-2 delivers reproducible kinetic energy transfer across all wells simultaneously, making it suitable for applications requiring precise agitation control, including ELISA incubation, cell-based assays, enzymatic reactions, and plate-based washing protocols. Its dual-platform architecture enables independent operation of two microplate decks, supporting parallel workflows without hardware duplication.

Key Features

• Dual independent shaking platforms—each accommodating standard ANSI/SLAS-compliant microplates (up to 2 plates concurrently)
• Adjustable orbital speed range from 100 to 1200 rpm, calibrated and traceable to internal reference standards
• Precise digital timer with programmable duration from 1 minute to 8 hours; auto-stop function with audible alert
• Compact benchtop footprint (285 × 220 × 145 mm) optimized for biosafety cabinets and crowded lab environments
• Brushless DC motor ensuring long-term stability, low noise (<55 dB at 1 m), and minimal heat generation during extended operation
• Non-slip silicone mat surface on each platform to prevent plate displacement under high-speed conditions
• Front-panel LED display with intuitive rotary encoder interface—no software installation required for basic operation

Sample Compatibility & Compliance

The MPM-2 supports all common microplate formats—including flat-bottom, round-bottom, V-bottom, and skirted plates—as well as PCR plates and shallow-well assay plates. Its 4 mm orbit is empirically validated to maintain liquid integrity in volumes ranging from 50 µL to 300 µL per well at speeds up to 1000 rpm. The device complies with IEC 61010-1:2010 safety standards for laboratory electrical equipment and meets EMC requirements per EN 61326-1:2013. While not certified for use in regulated GMP/GLP environments out-of-the-box, its stable performance profile and repeatable timing/frequency output support method validation under ISO/IEC 17025 quality systems. Users performing FDA-regulated assays may integrate the MPM-2 into controlled workflows where operational parameters are documented and maintained per SOP.

Software & Data Management

The MPM-2 operates as a standalone instrument with no proprietary software dependency. All settings are retained in non-volatile memory after power cycling. For labs requiring audit trails or remote monitoring, optional RS-232 or USB-to-serial interfaces (available via accessory module) allow integration with Lab Information Management Systems (LIMS) or custom Python/Node.js scripts for parameter logging. Timestamped runtime data—including start time, duration, and final speed setting—can be exported for compliance documentation. The device does not implement FDA 21 CFR Part 11 electronic signature functionality; however, its deterministic behavior and lack of user-modifiable firmware simplify qualification under Annex 11 or ALCOA+ data integrity principles.

Applications

• ELISA and immunoassay plate incubation with controlled agitation to enhance antigen-antibody binding kinetics
• Cell culture plate mixing prior to harvesting or passaging, minimizing sedimentation-induced heterogeneity
• Pre-incubation agitation for qPCR master mix preparation and distribution
• Consistent resuspension of lyophilized reagents or cryopreserved cell pellets in multi-well plates
• Supporting automated liquid handling workflows by pre-mixing plates before robotic aspiration
• QC testing of microplate seal integrity under dynamic shear stress conditions

FAQ

Can the MPM-2 accommodate 384-well plates?

Yes—the 4 mm orbit and low-center-of-gravity design ensure stable agitation for both 96-well and 384-well plates without edge-well spillage.
Is speed calibration traceable to national standards?

The factory calibration uses a NIST-traceable tachometer; users may perform periodic verification using external optical tachometers per ISO 17025 procedures.
Does the unit support continuous operation beyond 8 hours?

No—the maximum timer setting is 8 hours; for unattended overnight runs, external programmable power controllers must be used.
Are replacement silicone mats available as consumables?

Yes—Titan supplies OEM-compatible silicone mats (Part No. MPM-MAT-SIL-2) with chemical resistance to 70% ethanol, 0.5% SDS, and common buffer solutions.
What is the operating temperature range for safe use?

The MPM-2 is rated for ambient operation between 5 °C and 40 °C at ≤80% non-condensing relative humidity.