Titan MRC-18K Plus Benchtop High-Speed Refrigerated Centrifuge (Rotors Sold Separately)
| Brand | Titan |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Direct Manufacturer |
| Instrument Type | Benchtop Centrifuge |
| Speed Range | High-Speed (10,000–30,000 rpm) |
| Function | Refrigerated Centrifuge |
| Configuration | Fixed-Angle Rotor Compatible |
| Max Capacity | 4 × 250 mL |
| Max Speed | 18,000 rpm |
| Max RCF | 24,100 × g |
| Dimensions (W × D × H) | 560 × 680 × 376 mm |
| Cooling System | Compressor-Based Active Refrigeration |
| Temperature Range | –20 °C to +40 °C |
| Drive System | Brushless DC Motor |
| Control Interface | Touchscreen with Programmable Protocols |
| Safety Certification | IEC 61010-2-020, EN 61326-1 |
Overview
The Titan MRC-18K Plus is a high-performance benchtop refrigerated centrifuge engineered for precision separation of biological, clinical, and industrial samples under controlled thermal conditions. Utilizing a brushless DC motor and advanced compressor-based cooling system, it maintains precise temperature stability from –20 °C to +40 °C during operation—critical for preserving thermolabile macromolecules such as nucleic acids, enzymes, and exosomes. Its maximum rotational speed of 18,000 rpm delivers a relative centrifugal force (RCF) of up to 24,100 × g, enabling efficient pelleting of subcellular particles, microorganisms, and precipitated proteins. Designed for laboratory environments where space efficiency and operational reliability are paramount, the MRC-18K Plus complies with international safety standards IEC 61010-2-020 (for centrifuges) and EN 61326-1 (EMC requirements), ensuring safe integration into regulated workflows.
Key Features
- Robust brushless DC motor with extended service life and minimal maintenance requirements
- Active refrigeration system with rapid cooldown (<15 min from ambient to –20 °C) and ±1 °C temperature accuracy across full speed range
- Intuitive touchscreen interface supporting up to 99 user-programmable protocols with parameter locking and password protection
- Automatic rotor recognition via embedded RFID tags (compatible with optional Titan-certified fixed-angle rotors)
- Real-time imbalance detection with automatic deceleration and audible/visual alerts
- Double-layer reinforced stainless-steel chamber with sealed rotor cavity to prevent condensation ingress and cross-contamination
- Low-noise operation (<65 dB(A) at 18,000 rpm) suitable for shared laboratory spaces
Sample Compatibility & Compliance
The MRC-18K Plus supports standard conical-bottom polypropylene and polycarbonate tubes (e.g., 15 mL, 50 mL, and 250 mL formats), as well as specialized ultracentrifuge-compatible bottles when used with certified angle rotors. It accommodates common biosafety level 2 (BSL-2) sample handling requirements and meets mechanical integrity criteria outlined in ISO 13485 for in vitro diagnostic manufacturing environments. While not classified as a medical device per FDA 21 CFR Part 820, its design facilitates GLP/GMP-aligned documentation through audit-trail-capable protocol logging (when paired with Titan’s optional CentriLog™ software). All rotors must be purchased separately and validated for compatibility prior to use; unauthorized third-party rotors void warranty and compromise safety certification.
Software & Data Management
The onboard control system stores run logs—including time, speed, RCF, temperature, rotor ID, and acceleration/deceleration profiles—for traceability. Optional CentriLog™ PC software enables export of CSV-formatted datasets, remote monitoring via Ethernet/Wi-Fi, and integration with LIMS platforms using HL7 or ASTM E1384-compliant data structures. Audit trail functionality records operator login, parameter changes, and emergency stops with timestamped user IDs—supporting compliance with FDA 21 CFR Part 11 requirements when deployed with electronic signature modules. Firmware updates are delivered via secure USB key with SHA-256 checksum verification.
Applications
- Isolation of plasma, serum, and PBMCs from whole blood in clinical diagnostics laboratories
- Purification of plasmid DNA, viral vectors, and lipid nanoparticles in bioprocessing development
- Clarification of bacterial lysates and protein expression supernatants in R&D settings
- Sedimentation of nanomaterials and colloidal suspensions for materials science characterization
- Preparative fractionation of organelles (e.g., mitochondria, lysosomes) using density gradient protocols
- Routine QC testing of vaccine formulations requiring cold-chain integrity during centrifugation
FAQ
Is the MRC-18K Plus compliant with ISO 13485 or GMP requirements?
Yes—the unit’s mechanical design, documentation package, and optional CentriLog™ software support alignment with ISO 13485 quality management systems and GMP Annex 11 data integrity expectations when implemented with appropriate SOPs and validation protocols.
Can I use non-Titan rotors with this centrifuge?
No. Only Titan-certified rotors with integrated RFID identification are supported. Use of uncertified rotors invalidates safety certifications and voids the product warranty.
What is the minimum operating temperature, and how quickly does it stabilize?
The system achieves –20 °C within 15 minutes from ambient (25 °C) and maintains ±1 °C stability throughout the entire speed range, verified per ISO 21602 Annex B thermal performance testing.
Does the centrifuge include rotor balancing assistance?
Yes—integrated load-sensing electronics detect mass asymmetry exceeding 5 g per tube position and halt acceleration before unsafe conditions develop.
Is remote diagnostics or firmware update capability available?
Firmware updates require authenticated USB media; remote diagnostics are not enabled by default but can be activated via CentriLog™ software under IT-controlled network policies.
