Titan LRC-4K Max Benchtop Low-Speed Refrigerated Centrifuge
| Brand | Titan |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Direct Manufacturer |
| Instrument Type | Benchtop Centrifuge |
| Speed Range | Up to 6,000 rpm |
| Max RCF | 5,690 × g |
| Max Capacity | 4 × 750 mL (horizontal rotor configuration) |
| Temperature Range | -20 °C to +40 °C |
| Dimensions (W×D×H) | 750 × 663 × 407 mm |
| Compliance | Designed for GLP-compliant laboratories |
Overview
The Titan LRC-4K Max is a high-capacity benchtop low-speed refrigerated centrifuge engineered for routine separation tasks requiring precise temperature control and robust mechanical stability. Operating on the principle of sedimentation under controlled gravitational force (RCF), it enables efficient pelleting of cells, organelles, precipitates, and macromolecular complexes without thermal degradation. Its design prioritizes operational safety, reproducible performance, and integration into regulated laboratory workflows—particularly where sample integrity at sub-ambient temperatures is critical, such as in clinical hematology, biobanking, and upstream bioprocessing.
Key Features
- Refrigerated operation with independent compressor-based cooling system, maintaining setpoint accuracy within ±1 °C across the full range (–20 °C to +40 °C)
- Brushless DC motor delivering smooth acceleration/deceleration profiles and extended service life with minimal maintenance
- Four-position horizontal rotor configuration supporting up to 4 × 750 mL bottles or equivalent tube formats (e.g., 32 × 50 mL conical tubes), optimized for high-volume clinical or industrial batch processing
- Intelligent imbalance detection with automatic rotor deceleration and audible/visual alerts compliant with IEC 61010-2-020 safety requirements
- Corrosion-resistant stainless-steel chamber and rotor housing, certified for use with common disinfectants including 70% ethanol and sodium hypochlorite solutions
- Programmable memory for up to 99 user-defined protocols, each storing speed, time, temperature, and brake profile settings
Sample Compatibility & Compliance
The LRC-4K Max accommodates standard centrifuge vessels including polypropylene and polycarbonate bottles (up to 750 mL), conical tubes (15–50 mL), and swing-bucket adapters for microtubes. It supports applications involving whole blood, plasma, serum, cell suspensions, tissue homogenates, and polymer solutions. The unit is manufactured under ISO 13485-certified quality management systems and conforms to electromagnetic compatibility (EMC) directives (EN 61326-1) and electrical safety standards (EN 61010-1). While not classified as an IVD device per se, its thermal and mechanical consistency supports compliance with CLIA, CAP, and ISO 15189 quality assurance frameworks when deployed in accredited clinical labs.
Software & Data Management
The integrated control interface features a 7-inch capacitive touchscreen with intuitive icon-driven navigation and real-time display of RCF, rpm, elapsed time, remaining time, chamber temperature, and rotor status. All run logs—including start/stop timestamps, parameter sets, error codes, and door cycle history—are stored internally with non-volatile memory retention (>10,000 cycles). Optional RS-485 and USB-C ports enable data export to LIMS or ELN platforms; audit trail functionality satisfies basic FDA 21 CFR Part 11 requirements for electronic record integrity when paired with institutional validation protocols.
Applications
- Clinical diagnostics: Separation of erythrocytes, leukocytes, and platelets from whole blood; preparation of serum/plasma for immunoassays and coagulation testing
- Biopharmaceutical manufacturing: Clarification of microbial or mammalian cell culture harvests prior to downstream filtration or chromatography
- Academic research: Isolation of nuclei, mitochondria, and lysosomal fractions from tissue homogenates using differential centrifugation protocols
- Food and environmental testing: Sedimentation of suspended solids in water samples or extraction of fat layers from dairy emulsions
- Veterinary labs: Processing of large-volume serum batches from livestock sera for antibody titer analysis
FAQ
What is the minimum operating temperature and how quickly does the chamber reach –20 °C?
The refrigeration system achieves –20 °C from ambient (25 °C) in approximately 18 minutes under no-load conditions.
Is rotor calibration traceable to national standards?
Yes—each rotor undergoes factory balancing and RCF verification using NIST-traceable tachometry and gravimetric methods; calibration certificates are supplied with initial delivery.
Can the LRC-4K Max be validated for GMP environments?
The platform supports IQ/OQ documentation packages and includes configurable password-protected access levels for operators, supervisors, and administrators—enabling alignment with Annex 11 and EU GMP Chapter 4 requirements.
Does it support continuous operation at maximum speed and temperature?
Yes—rated for uninterrupted runs up to 99 hours and 59 minutes at any combination of speed and temperature within specification limits.
Are third-party rotors compatible?
Only Titan-certified rotors are supported; use of non-OEM components voids warranty and compromises safety certification.
