Masterflex I/P Programmable Split-Body Peristaltic Pump

Overview

The Masterflex I/P Programmable Split-Body Peristaltic Pump is an industrial-grade, precision fluid transfer system engineered for repeatable, contamination-free dosing and continuous pumping in regulated laboratory, bioprocessing, and analytical environments. Based on the well-established peristaltic principle—where rollers compress flexible tubing to generate positive displacement—the I/P series separates the motor drive unit from the controller, enabling flexible installation (desktop or wall-mounted) and remote operation over distances up to 7.6 m via shielded cable. This architecture eliminates direct electrical coupling between control electronics and motor, enhancing electromagnetic compatibility (EMC) and simplifying integration into automated workflows governed by GLP, GMP, or FDA 21 CFR Part 11 requirements. The pump’s modular design supports dual-head configurations for parallel or blended fluid handling, while its programmable logic allows deterministic volume delivery, timed intervals, and cycle repetition without external PLC intervention.

Key Features

• Split-body architecture with detachable motor and controller units—enabling desktop (07592-27) or IP56-rated wall-mount (07592-35) deployment
• Backlit LED display showing real-time parameters: flow rate (mL/min), rotational speed (rpm), cumulative volume dispensed (mL/L), elapsed time (s/min/h), and cycle count
• Bidirectional operation with programmable pre- and post-run tube rinsing sequences to minimize carryover and cross-contamination
• Keyboard lock function prevents accidental parameter changes during unattended operation
• Onboard memory stores calibration offsets for multiple tubing sizes—automatically applied based on selected tubing ID/OD specifications
• High-resolution flow control with selectable resolution modes (0.01 mL, 1 mL, or 10 mL) synchronized with user-defined volume targets
• Analog and digital interface support: 0–20 mA / 4–20 mA current loops, 0–10 V analog input, and TTL pulse triggering for synchronization with external instruments or SCADA systems
• Robust mechanical design featuring hardened steel rollers, precision-machined housing, and sealed bearings rated for >10,000 hours of continuous operation under nominal load

Sample Compatibility & Compliance

The I/P pump accommodates a broad range of certified tubing materials—including silicone, platinum-cured silicone (e.g., Masterflex Bio-Platinum, Saint-Gobain Tygon B-44-4X, Pharmapure), fluoropolymer-reinforced elastomers (e.g., Chem-Durance, Norprene-A-60-G), and ultra-pure chemically inert options (e.g., Tygon 2475, Viton)—ensuring compatibility with aggressive solvents, biological buffers, pharmaceutical formulations, and food-grade media. Tubing selection directly determines flow range (0.12–19 L/min) and dispensing accuracy (±2–8.8 mL per 1000 mL, depending on tubing geometry and fluid viscosity). All controllers comply with CE (EN 61326-1), cULus (UL 61010-1), and ISO 9001:2000 quality management standards. The wall-mount controller’s IP56 rating provides protection against dust ingress and water jets, making it suitable for wet-lab or cleanroom perimeter installations where splash resistance is required.

Software & Data Management

While the I/P pump operates autonomously via front-panel programming, its analog/digital I/O enables seamless integration with third-party data acquisition platforms (e.g., LabVIEW, MATLAB, or custom SCADA). For audit-trail compliance in regulated settings, users may log operational events—including start/stop timestamps, volume totals, error codes, and calibration history—via external recording systems triggered by TTL pulses or 4–20 mA feedback signals. The pump does not include embedded firmware-based electronic records; however, its deterministic behavior, calibrated repeatability (±0.5% flow accuracy), and hardware-level parameter locking support validation protocols aligned with FDA 21 CFR Part 11 when paired with compliant data capture infrastructure. Calibration data for each tubing type is stored locally and recalled automatically upon selection—reducing operator-dependent variability and supporting IQ/OQ documentation.

Applications

• Automated reagent dispensing in clinical chemistry analyzers and ELISA workstations
• Continuous feed of cell culture media or harvest streams in bioreactor auxiliary systems
• Accurate metering of high-viscosity fluids (e.g., glycerol, polymer solutions) using thick-walled tubing (e.g., #70, #88, #89)
• Multi-channel sample dilution or blending via dual-head configuration with Y-connector manifolds
• In-line filtration priming and buffer exchange in HPLC or FPLC auxiliary circuits
• Controlled perfusion in organ-on-chip and microfluidic experimental rigs
• Food and beverage QC sampling where sanitary tubing changeout and traceability are critical

FAQ

What tubing types are validated for use with the Masterflex I/P pump?

The pump is compatible with all Masterflex-certified tubing—including silicone, C-Flex, Tygon LFL, Pharmapure, Norprene, and Chem-Durance—as well as equivalent tubing from Saint-Gobain and Dow Corning meeting dimensional and durometer specifications. Validation data for chemical resistance and extractables is available per USP Class VI and FDA CFR Title 21 guidelines.

Can the pump be integrated into a GMP-compliant manufacturing process?

Yes—when deployed with documented calibration procedures, operator training records, and external electronic logging of operational parameters, the I/P pump meets baseline requirements for equipment qualification (IQ/OQ) in pharmaceutical and medical device production environments.

Is dual-head operation supported on both desktop and wall-mount models?

Dual-head capability is hardware-enabled on both versions; however, only the wall-mount controller (07592-35) includes dedicated mounting provisions for secondary pump heads and integrated Y-manifold routing.

How is flow accuracy maintained across varying fluid viscosities?

Accuracy is preserved through tubing-specific calibration offsets and low-slip roller geometry. For fluids >1,000 cP, thick-walled tubing (#70, #88, #89) is recommended to maintain occlusion integrity and minimize slippage-induced deviation.

Does the pump support remote start/stop via network protocol (e.g., Ethernet/IP or Modbus)?

No native Ethernet or fieldbus interface is included; however, analog (4–20 mA) and digital (TTL) I/O allow integration with industrial gateways or PLCs supporting those protocols.