Masterflex L/S Peristaltic Pump System (Model 77913-45, Remote Controller with No Display)

Overview

The Masterflex L/S Peristaltic Pump System (Model 77913-45) is a precision-engineered, industrial-grade peristaltic pump designed for reliable, contamination-free fluid transfer in demanding laboratory and pilot-scale applications. Based on the proven L/S (Larger-Scale) platform, this system operates on the principle of positive displacement via roller compression of flexible tubing—eliminating valves, seals, and internal wetted parts to ensure absolute fluid isolation and prevent cross-contamination. Its modular architecture separates the control unit from the motor head via a 9.3-meter shielded cable, enabling remote operation in hazardous, high-humidity, or chemically aggressive environments where direct access is impractical or unsafe. The system supports bidirectional rotation and manual speed adjustment via calibrated torque knob, providing intuitive, analog control without reliance on digital interfaces—ideal for GLP-compliant workflows requiring audit-trail simplicity and operational robustness.

Key Features

• Modular controller–motor configuration with 9.3 m interconnect cable for spatial separation and environmental resilience
• 4–20 mA analog remote speed input with fail-safe stop logic (<4 mA triggers immediate halt)
• Bidirectional operation for forward/reverse priming, cleaning, and recirculation protocols
• Two distinct controller families: 07553-series (IP23 controller / IP21 motor; ±2% speed accuracy) and 07552-series (IP56 controller / IP34 motor; ±10% speed accuracy), optimized for different environmental severity levels
• Support for multiple pump heads—including Easy-Load® 3 (77800-60), Easy-Load® II (77200-62), and standard L/S heads—enabling rapid tube changes without tools
• Compatible with Tygon® LFL long-life tubing in 12 standard sizes (ID 0.8–9.6 mm), including thick-wall variants (e.g., #15, #24, #35) for enhanced suction lift and high-viscosity handling
• Compliance with ISO 9001:2000 quality management standards and CE marking per applicable EU directives (07553-77, 07553-87)

Sample Compatibility & Compliance

The 77913-45 system accommodates a broad range of fluid types—including aqueous buffers, organic solvents, cell culture media, slurries, and mildly abrasive suspensions—through selection of chemically compatible tubing materials (e.g., Tygon LFL, PharMed BPT, Viton). Its tube-based fluid path ensures full compatibility with USP Class VI, FDA 21 CFR Part 11 (when integrated with compliant data acquisition systems), and ISO/IEC 17025 traceability requirements. The absence of internal wetted surfaces eliminates risk of metal leaching or surface adsorption, making it suitable for low-concentration analyte delivery in HPLC sample introduction, bioreactor feed control, and reagent dispensing under GMP conditions. All configurations meet IEC 61000-6-2 (immunity) and IEC 61000-6-4 (emission) electromagnetic compatibility standards.

Software & Data Management

As a hardware-only analog-controlled system, the 77913-45 does not include embedded firmware or onboard data logging. However, its 4–20 mA interface enables seamless integration into centralized SCADA, DCS, or PLC environments for real-time speed setpoint synchronization and status monitoring. When paired with third-party analog-to-digital converters and validated software platforms (e.g., LabVIEW, DeltaV, or custom Python-based acquisition tools), the system supports full electronic record generation with time-stamped speed logs, runtime hours, and alarm events—meeting ALCOA+ principles for data integrity in regulated laboratories. Audit trails, user access controls, and electronic signatures can be implemented at the supervisory system level, satisfying FDA 21 CFR Part 11 requirements for electronic records and signatures.

Applications

• Continuous feeding of culture media or pH-adjusting agents in bioreactors and fermenters
• Low-shear transfer of shear-sensitive biologicals (e.g., viral vectors, exosomes, primary cells)
• Calibration fluid delivery in analytical instrument validation (e.g., ICP-MS, IC, TOC analyzers)
• Waste stream sampling and inline dilution in environmental monitoring stations
• Multi-channel reagent addition in automated ELISA or PCR setup workstations
• Pilot-scale chromatography fraction collection with synchronized flow-rate ramping
• Chemical dosing in corrosion inhibition or water treatment test loops

FAQ

What is the difference between the 07553 and 07552 controller series?
The 07553 series offers higher speed accuracy (±2%) and lower IP ratings (IP23/IP21), prioritizing precision in controlled lab environments. The 07552 series trades some accuracy (±10%) for superior ingress protection (IP56/IP34), making it better suited for washdown or outdoor deployment.
Can multiple pump heads be operated simultaneously from one controller?
Yes—up to four L/S pump heads may be daisy-chained using compatible multi-head brackets (e.g., 07553-85/87 configurations), maintaining identical speed across all channels for parallel processing or flow summation via Y-fittings.
Which tubing sizes are supported by the Easy-Load® 3 pump head included in 77913-45?
The 77800-60 Easy-Load® 3 head accepts tubing sizes #13, #14, #16, #25, #17, and #18 (ID 0.8–8.0 mm), delivering flow rates from 0.06 to 480 mL/min depending on tube selection and rotational speed.
Is the pump suitable for sterile applications?
While the pump itself is not sterilizable, its tube-based design allows use of gamma-irradiated, pre-sterilized tubing (e.g., C-Flex SR, Pharmed BPT) in closed-system transfers, supporting aseptic process validation when combined with appropriate tubing change SOPs and environmental controls.
Does the system require calibration verification per ISO/IEC 17025?
Yes—users must perform periodic volumetric flow verification using gravimetric or timed-collection methods traceable to NIST standards. Masterflex provides flow rate reference tables per tubing size and RPM; however, end-user validation under actual operating conditions is required for accredited testing laboratories.