Sartorius Secura125-1CN Semi-Micro Balance
| Brand | Sartorius |
|---|---|
| Origin | Germany |
| Model | Secura125-1CN |
| Type | Analytical Balance |
| Maximum Capacity | 120 g |
| Readability | 0.01 mg (100 µg) |
| Repeatability | 0.02 mg / 0.04 mg (typical standard deviation) |
| Calibration | Internal, isoCAL automatic adjustment |
| Data transfer | Plug-and-Play USB to PC (no driver required) |
| Weighing pan diameter | 80 mm (90 mm optional) |
| Draft shield height | 218 mm |
| Dimensions (D×W×H) | 376 × 214 × 316 mm |
| Net weight | 7.8 kg |
Overview
The Sartorius Secura125-1CN is a high-precision semi-micro balance engineered for laboratories requiring traceable, reproducible mass measurements at the 0.01 mg readability level. Designed and manufactured in Germany, it operates on electromagnetic force compensation (EMFC) principle — the industry-standard method for analytical and semi-micro balances — ensuring exceptional linearity, stability, and long-term drift resistance across its 120 g maximum capacity range. Its core architecture integrates metrological rigor with regulatory readiness: every weighing event, calibration action, and system adjustment is timestamped, user-identified, and auditable — fulfilling foundational requirements for ISO/IEC 17025-accredited testing labs, pharmaceutical QC environments governed by USP & EP monographs, and manufacturing sites operating under FDA 21 CFR Part 11 and EU Annex 11 compliance frameworks.
Key Features
- isoCAL™ Automatic Internal Calibration: Fully automated temperature- and time-triggered recalibration using built-in reference weights. Adjustable calibration intervals (default: 4 h) and sensitivity thresholds (±1.5 K) ensure continuous metrological validity without manual intervention. All calibrations are logged with full audit trail including operator ID, timestamp, ambient temperature, and deviation values.
- LevelControl™ Real-Time Level Monitoring: Integrated tilt sensor continuously monitors horizontal alignment. Upon detection of deviation, the display guides users step-by-step through physical leveling — eliminating subjective bubble-level interpretation and reducing setup error risk before first use or relocation.
- Plug-and-Play Data Connectivity: Native USB interface enables direct, driver-free data transmission to spreadsheet applications (e.g., Microsoft Excel), LIMS, or ELN systems. Weighing results appear instantly as numeric entries — no middleware software or configuration required — accelerating data entry and minimizing transcription errors.
- GLP/GMP-Ready Documentation: Built-in printer support (YDP30 compatible) generates fully compliant reports containing date/time stamp, operator ID, balance ID, sample/batch ID (user-defined alphanumeric tags), net/gross/tare values, and environmental conditions (if external sensors connected). Optional PDF export via optional software modules supports 21 CFR Part 11 electronic signature workflows.
- Protected Configuration Management: Password-protected access controls prevent unauthorized modification of critical parameters (e.g., filter settings, print formats, calibration thresholds), preserving measurement integrity and supporting laboratory SOP enforcement.
- Optimized Mechanical Design: Draft shield with 218 mm internal height and 80 mm (or optional 90 mm) stainless steel weighing pan ensures stable operation in non-laminar airflow environments. The robust die-cast aluminum housing dampens mechanical vibration while maintaining thermal inertia for rapid stabilization (~6 s typical settling time).
Sample Compatibility & Compliance
The Secura125-1CN accommodates a broad spectrum of solid and powder samples common in pharmaceutical formulation, reference standard preparation, catalyst dosing, and nanomaterial synthesis. Its 120 g capacity and 0.01 mg resolution meet USP minimum weight requirements for high-potency APIs (minimum sample weight = 25 mg per USP criteria). The balance conforms to OIML R 76-1 Class I accuracy specifications and is type-approved per EN 12334 for legal-for-trade applications where applicable. Full traceability is assured through factory calibration against NIST-traceable standards, with certificate of conformity supplied. All firmware and calibration logic comply with ISO 9001:2015 and ISO/IEC 17025:2017 documentation control requirements.
Software & Data Management
No proprietary software installation is required for basic operation or data export. However, Sartorius LabX® Lite (free download) extends functionality with customizable report templates, multi-balance fleet monitoring, statistical process control (SPC) charting, and electronic signature integration. All internal logs — including Cal Audit Trail, LevelControl history, and weighing session metadata — are exportable in CSV or XML format for archival in validated document management systems. Firmware updates are delivered via secure HTTPS and require digital signature verification prior to installation, satisfying cybersecurity provisions of IEC 62443-3-3.
Applications
- Quantitative preparation of certified reference materials (CRMs) and working standards
- Weighing of active pharmaceutical ingredients (APIs) and excipients in GMP-compliant formulation suites
- Calibration of pipettes and volumetric glassware per ISO 8655
- Research-scale synthesis where stoichiometric precision at sub-milligram levels is critical
- Quality control of microelectronics components and thin-film deposition substrates
<li gravimetric analysis in environmental testing (e.g., filter mass change in PM2.5 sampling)
FAQ
What does “0.01 mg readability” mean in practice?
It indicates the smallest mass increment the balance can resolve and display — equivalent to 10 µg. This resolution supports USP minimum weight calculations for high-potency compounds and enables reliable measurement of samples ≥25 mg under standard lab conditions.
Is isoCAL calibration traceable to national standards?
Yes. Each isoCAL event references the balance’s internal mass standard, which is factory-calibrated against Sartorius’ primary standards traceable to PTB (Physikalisch-Technische Bundesanstalt) and NIST. Full calibration certificates are available upon request.
Can the Secura125-1CN be integrated into a networked LIMS environment?
Yes — via USB-to-PC connection and LabX® software, or through ASCII protocol over RS232 (with optional interface module). All data fields are configurable for seamless mapping to LIMS data dictionaries.
Does the balance support dynamic weighing or density determination?
No — the Secura125-1CN is optimized for static, high-accuracy mass measurement only. For density or moisture analysis, Sartorius offers dedicated instruments (e.g., MSA series for density, MA series for moisture).
How often must the balance be externally serviced?
Sartorius recommends annual performance verification by an accredited service provider. The built-in diagnostics, Cal Audit Trail, and LevelControl history provide objective evidence for interval extension decisions per ISO/IEC 17025 Clause 6.4.10.
