Rainin Pipet-Lite XLS+ Single-Channel Manual Pipette
| Brand | Rainin |
|---|---|
| Origin | USA |
| Model | L-10XLS+, L-20XLS+, L-100XLS+ |
| Type | Single-Channel Manual Pipette |
| Channels | 1 |
| Volume Range | 0.5–2000 µL |
| Maximum Capacity | 2000 µL |
| Accuracy | ±1% at 20 µL, ±0.8% at 200 µL |
| Sterilization | Fully autoclavable (liquid end, tip ejector, and sleeve) |
| Compliance | GLP/GMP-ready with embedded RFID for calibration traceability |
| Ergonomics | Magnetic Assist™ piston mechanism, LTS™ LiteTouch System, low-force plunger actuation, glove-friendly volume adjustment |
Overview
The Rainin Pipet-Lite XLS+ Single-Channel Manual Pipette is an engineered precision liquid handling instrument designed for high-reproducibility volumetric transfer in regulated laboratory environments. Based on air displacement principle, it delivers consistent aspiration and dispensing across its full operational range—from 0.5 µL to 2000 µL—without electronic components or power requirements. Its mechanical architecture integrates patented Magnetic Assist™ technology, which uses calibrated magnetic coupling to reduce plunger activation force by up to 50% compared to conventional manual pipettes. This design minimizes operator-induced variability and fatigue during repetitive tasks, supporting compliance with ISO 8655-2 (volumetric accuracy and precision testing) and enabling reliable performance under GLP and GMP workflows.
Key Features
- Magnetic Assist™ piston system ensures smooth, low-force plunger movement with consistent stroke resistance across all volumes—critical for reducing inter-operator variability.
- LTS™ (LiteTouch System) lightweight tip ejection mechanism requires only 30% of the force of standard systems, minimizing hand strain and improving control during high-throughput operations.
- Fully autoclavable construction: entire liquid end—including O-rings, seals, and polymer tip ejector—is rated for repeated steam sterilization at 121°C for 20 minutes without degradation in accuracy or tactile response.
- Glove-compatible volume adjustment dial features anti-jam geometry and tactile click feedback, preventing accidental volume shifts during routine use.
- Embedded RFID tag stores unique serial number, calibration history, maintenance logs, and user-defined metadata—enabling seamless integration with LabVantage, STARLIMS, or custom LIMS platforms.
- Ergonomic sleeve design with textured, non-slip grip surface reduces wrist flexion angle by 12° versus legacy models, validated per ISO 11228-3 (manual handling ergonomics).
Sample Compatibility & Compliance
The Pipet-Lite XLS+ is compatible with all universal-fit and LTS-certified pipette tips, including low-retention, filtered, and sterile variants. Its sealed liquid path prevents aerosol ingress and cross-contamination, meeting ASTM E2914-13 requirements for contamination control in molecular diagnostics. The device conforms to ISO 8655-1 through -6 for specification, testing, and calibration of piston-operated volumetric apparatus. Built-in RFID supports 21 CFR Part 11-compliant audit trails when paired with validated software clients, fulfilling documentation requirements for pharmaceutical QC labs and clinical research facilities operating under FDA or EMA oversight.
Software & Data Management
Each unit contains a passive, read-only RFID chip (ISO 15693 compliant) programmed at manufacture with immutable identifiers and factory calibration data. When scanned via Rainin ProFlow Reader or third-party RFID-enabled workstations, the chip transmits timestamps, calibration due dates, service records, and user-assigned asset tags. Data export is supported in CSV and XML formats for ingestion into ELN systems or automated calibration management platforms. No proprietary software installation is required—interfacing relies solely on industry-standard NFC/RFID protocols, ensuring long-term interoperability and avoiding vendor lock-in.
Applications
This pipette serves as a foundational tool in applications demanding high volumetric fidelity and operator sustainability: quantitative PCR setup, ELISA plate preparation, cell culture passaging, compound dilution in drug discovery, and reference standard preparation for HPLC and mass spectrometry workflows. Its ultra-low-volume capability (down to 0.5 µL) makes it suitable for nanoliter-scale assays such as single-cell RNA-seq library prep and CRISPR guide RNA titration. The autoclavability and chemical resistance of its polymer components also support use in biosafety level 2 (BSL-2) containment labs handling infectious agents or hazardous compounds.
FAQ
Is the Pipet-Lite XLS+ compatible with non-Rainin pipette tips?
Yes—it accepts all universal-fit tips; however, optimal sealing, accuracy, and LTS functionality are guaranteed only with Rainin LTS-certified tips.
Can the RFID chip be rewritten or updated in-house?
No—the chip is factory-programmed and read-only. Calibration updates and service logs must be recorded externally in LIMS or ELN systems.
What is the recommended recalibration interval?
Per ISO 8655-5, verification should occur before each shift in high-precision applications; formal recalibration is advised every 3–6 months depending on usage frequency and criticality of assay outcomes.
Does the pipette retain accuracy after repeated autoclaving?
Yes—validation data per ISO 17025-accredited testing confirms no statistically significant deviation in accuracy or repeatability after 50 autoclave cycles at 121°C.
How does Magnetic Assist™ differ from spring-assisted mechanisms in competitive models?
Unlike linear spring systems subject to hysteresis and fatigue, Magnetic Assist™ employs repulsive magnetic fields to generate consistent, wear-free resistance—ensuring identical plunger feel across the instrument’s lifetime.




