Sartorius Quintix125D-1CN Analytical Balance with 0.01 mg Readability

Overview

The Sartorius Quintix125D-1CN is a high-precision analytical balance engineered for demanding laboratory environments where trace-level mass quantification, regulatory compliance, and operational reproducibility are critical. Operating on electromagnetic force compensation (EMFC) principle, it delivers consistent 0.01 mg readability across its 120 g maximum capacity range. Designed and assembled in Sartorius’ ISO 9001-certified manufacturing facility in Shanghai, the Quintix125D-1CN meets the metrological requirements of ISO/IEC 17025 accredited laboratories and supports GLP/GMP workflows through full audit trail functionality and secure user management. Its robust monolithic weighing cell, integrated draft shield, and temperature-compensated transducer architecture minimize environmental drift—ensuring measurement stability under typical lab conditions (20–25 °C, <60 % RH).

Key Features

• Full-color 4.3-inch capacitive touchscreen interface with intuitive icon-based navigation—no manual required for routine weighing, formulation, or statistics.
• isoCAL — fully automatic internal calibration and adjustment system triggered by temperature deviation ≥1.5 K or at programmable intervals (default: every 4 hours), eliminating manual intervention and ensuring continuous traceability to national standards.
• Direct PC connectivity via USB-B port: enables seamless data export to Excel, LIMS, or ELN systems without proprietary drivers; supports Windows/macOS/Linux.
• Integrated Sartorius printer interface (USB or RS-232) for immediate hardcopy generation of weight records with timestamp, operator ID, and balance serial number.
• Multi-level user administration with password protection, role-based permissions (e.g., Operator, Supervisor, Administrator), and encrypted audit trail compliant with FDA 21 CFR Part 11 requirements.
• Modular draft shield design with front sliding door and side access ports accommodates volumetric flasks, weighing boats, and tall containers while maintaining aerodynamic stability.

Sample Compatibility & Compliance

The Quintix125D-1CN supports a broad spectrum of sample forms—including powders, granules, liquids in tared vessels, filter papers, and microcentrifuge tubes—thanks to its 80 mm standard weighing pan (90 mm optional) and 218 mm clearance beneath the draft shield. It conforms to OIML R 76-1 Class I accuracy specifications for analytical balances and satisfies metrological criteria outlined in USP , ASTM E898, and ISO 9001. All firmware and software modules undergo periodic validation per GAMP 5 guidelines. Calibration certificates issued by Sartorius-accredited service centers include uncertainty budgets traceable to PTB (Physikalisch-Technische Bundesanstalt) standards.

Software & Data Management

Embedded firmware supports real-time statistical evaluation (mean, SD, CV%, min/max), dynamic averaging, and gross/net/tare modes. Data logging includes date/time stamp, operator ID, balance ID, environmental conditions (optional external sensor input), and event markers (e.g., calibration, door open/close). Export formats include CSV, TXT, and XML. Optional Sartorius LabX® software provides centralized instrument control, method templates, electronic signatures, and automated report generation aligned with ALCOA+ data integrity principles. Audit trails are immutable, time-stamped, and exportable for regulatory inspection.

Applications

• Pharmaceutical quality control: active pharmaceutical ingredient (API) assay, reference standard weighing, dissolution tablet preparation.
• Academic and industrial research: catalyst mass dosing, nanomaterial synthesis quantification, isotopic tracer preparation.
• Environmental testing labs: gravimetric analysis of PM2.5 filters, TSS (total suspended solids) determination per EPA Method 160.2.
• Food & beverage QA: moisture content calculation, additive concentration verification, nutritional labeling compliance.
• Chemical manufacturing: high-purity reagent dispensing, stoichiometric reaction setup, batch release documentation.

FAQ

What does “0.01 mg readability” mean in practice?
It indicates the smallest increment the display can resolve under optimal conditions—not synonymous with accuracy or repeatability. Actual measurement uncertainty depends on environmental factors, calibration status, and sample handling; typical minimum sample weight is 25 mg to achieve ≤0.1 % relative standard deviation.
Is isoCAL sufficient for regulatory audits?
Yes—isoCAL fulfills the requirement for periodic calibration verification under ISO/IEC 17025 and USP . However, initial verification and annual full calibration must be performed using certified weights traceable to national metrology institutes.
Can the Quintix125D-1CN connect to a networked LIMS?
Via LabX software or third-party middleware supporting HL7 or ASTM E1384 protocols; direct Ethernet or Wi-Fi is not built-in, but USB-to-Ethernet adapters with compatible drivers enable indirect integration.
Does it support Good Manufacturing Practice (GMP) documentation?
Yes—when used with LabX or configured with enabled audit trail, electronic signatures, and locked configuration modes, it meets core GMP data integrity expectations per EU Annex 11 and FDA guidance.
What is the recommended recalibration frequency?
Daily isoCAL activation is standard; formal external calibration using class E2 weights is advised before first use, after relocation, following mechanical shock, and at least once per month—or per risk-based assessment defined in your laboratory’s SOPs.