LongerPump LSP01-2A Single-Channel Precision Syringe Pump

Overview

The LongerPump LSP01-2A is a single-channel, infusion-mode precision syringe pump engineered for reproducible, low-flow liquid delivery in life science laboratories. It operates on a stepper-motor-driven linear actuation principle, converting rotational motion into precise axial displacement of the syringe plunger. This electromechanical architecture enables accurate volumetric control without reliance on pressure feedback or closed-loop flow sensing—making it suitable for applications where stable, pulse-minimized infusion is critical, such as microfluidic cell perfusion, electrophysiology microinjection, and controlled reagent dosing in assay development. The LSP01-2A incorporates a 5× gear reduction mechanism compared to its predecessor (LSP01-1A), significantly reducing mechanical pulsation and enhancing flow smoothness—particularly advantageous in sensitive biological workflows including live-cell analysis and nanoliter-scale sample introduction.

Key Features

• High-resolution linear actuation: 0.03125 µm per step ensures sub-nanoliter dispensing repeatability over extended operation.
• Dual-input syringe configuration: Supports both preloaded syringe library selection (covering major global manufacturers and standard sizes) and manual inner-diameter entry (range: 0.1–30 mm) for full flexibility in custom or nonstandard hardware integration.
• Intuitive human-machine interface: Large backlit LCD display paired with rotary encoder and membrane keypad enables rapid parameter setup—flow rate, volume, time, or linear speed—with real-time unit switching between µL/min, mL/h, and mm/min.
• Robust mechanical protection suite: Integrated stall detection halts motor drive and triggers audible alarm upon mechanical obstruction; adjustable mechanical limit blocks prevent syringe barrel deformation or plunger overtravel.
• Non-volatile parameter retention: All operational settings—including target volume, flow profile, and calibration offsets—are stored in EEPROM. Upon power recovery, users may choose to resume prior operation or initiate a clean restart.
• Industrial-grade I/O and communication: RS-485 bus enables daisy-chain integration into centralized lab automation systems; two opto-isolated status outputs (start/stop, direction) and two configurable trigger inputs support synchronized multi-instrument protocols under PLC or PC-based orchestration.

Sample Compatibility & Compliance

The LSP01-2A accommodates glass, plastic, and metal syringes ranging from 0.5 µL microsyringes (e.g., Hamilton 700 series) up to 100 mL industrial barrels, provided the inner diameter falls within the supported range. Its open-syringe design allows direct mounting of OEM-compatible accessories such as pressure sensors, inline filters, or fluidic manifolds. While not certified for ISO 13485 or FDA 21 CFR Part 11 out-of-the-box, the pump’s deterministic behavior, traceable calibration routines, and audit-ready parameter logging (via external software) support compliance with GLP and GMP-aligned laboratory practices when deployed within validated workflows. All electrical components meet CE safety standards (EN 61010-1) and EMC directives (EN 61326-1).

Software & Data Management

The pump supports ASCII-based serial command protocol over RS-485, enabling seamless integration with LabVIEW, Python (PySerial), MATLAB, or custom SCADA platforms. LongerPump provides a Windows-based configuration utility that permits remote parameter editing, real-time monitoring of actual vs. setpoint flow, and export of timestamped operation logs (CSV format). For regulated environments, third-party middleware solutions can be deployed to enforce electronic signature capture, change control tracking, and 21 CFR Part 11-compliant audit trails. Calibration data—including volumetric correction factors derived from gravimetric or fluorometric validation—is stored per syringe ID and applied automatically during runtime.

Applications

• Cell biology: Continuous nutrient or drug perfusion in microfluidic organ-on-chip devices and 3D bioreactors.
• Neuroscience: Controlled microinjection of tracers, dyes, or viral vectors into brain tissue slices or in vivo preparations.
• Analytical chemistry: Precise mobile-phase delivery in capillary electrophoresis or nano-LC front-end coupling.
• Materials science: Metered deposition of polymer precursors or nanoparticle suspensions in thin-film fabrication.
• Quality control: Automated dilution series generation for ELISA standard curve preparation and reference material dispensing.

FAQ

What syringe sizes are compatible with the LSP01-2A?
The pump supports syringes with inner diameters from 0.1 mm to 30 mm—covering volumes from 0.5 µL microsyringes to 100 mL reservoirs. A built-in database includes common models from Hamilton, BD, Terumo, and SGE.
Does the LSP01-2A support bidirectional operation (infuse & withdraw)?
No—it operates exclusively in infusion mode. Withdrawal capability requires dual-mode pumps such as the LongerPump LSP02 series.
How is flow accuracy validated?
Accuracy is verified gravimetrically per ISO 8599:2021 Annex B using Class E2 weights and calibrated analytical balances; users may perform routine verification using the integrated liquid volume calibration function.
Can multiple LSP01-2A units be synchronized?
Yes—via RS-485 Modbus RTU addressing, up to 32 units can operate in coordinated start/stop and flow-ramp sequences under master controller supervision.
Is firmware upgrade supported?
Firmware updates are delivered via USB-to-RS485 adapter and executed through the official configuration software; version history and release notes are published on LongerPump’s technical documentation portal.