Delmic
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| Brand | Delmic |
|---|---|
| Origin | Netherlands |
| Model | Meteor / Meteor 2.0 |
| Integration Type | In-chamber cryo-fluorescence light microscope (cryo-FLM) for direct mounting on cryo-FIB/SEM dual-beam systems |
| Vacuum Compatibility | High-vacuum compatible (≤1×10⁻⁶ mbar) |
| Optical Resolution | Subcellular (≤300 nm lateral, dependent on NA and wavelength) |
| Field of View | Up to 500 µm × 400 µm (tile-scanned, stitched) |
| Imaging Modes | Widefield fluorescence, Z-stack acquisition, multi-channel sequential imaging |
| Excitation Sources | LED-based, configurable wavelengths (e.g., 405 nm, 488 nm, 561 nm, 640 nm) |
| Emission Filters | Motorized filter wheel with bandpass filters (FWHM ≤25 nm), minimal spectral crosstalk |
| Objective | High-NA apochromatic cryo-objective (e.g., 0.95 NA, 20× or 40×, corrected for ice thickness) |
| Detector | Back-illuminated sCMOS camera (QE >95% at 550 nm, read noise <1.5 e⁻ rms) |
| Software Platform | ODEMIS (open-source, Python-based), including ODEMIS Advanced for automated correlative workflows |
| Compliance | Designed for GLP/GMP-aligned cryo-EM workflows |