Unchained Labs
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| Brand | Unchained Labs |
|---|---|
| Origin | USA |
| Model | Junior-PVDS |
| Temperature Range | -20–120 °C |
| Dissolved Oxygen Range | 0–5 mg/L |
| pH Range | 1–14 |
| Vial Compatibility | 8–60 mm diameter |
| Max Tray Weight | 1000 g (including enclosure) |
| Hopper Capacity | Powdernium™: 10–100 mL |
| SV Dispenser | 4 mL |
| Dispense Volume | 10–10,000 µL |
| Viscosity Range (for viscous liquids) | 1–1000 cP |
| Balance Capacity | 220 g |
| Balance Sensitivity | 0.01 mg |
| Brand | Unchained Labs |
|---|---|
| Origin | USA |
| Model | Leprechaun |
| Application | Single-particle immuno-structural analysis of lentiviral vectors and extracellular vesicles (e.g., exosomes) |
| Detection Principle | Fluorescence-based single-particle imaging coupled with antibody- and probe-mediated orthogonal labeling |
| Sensitivity | ≥1 × 10⁷ particles/mL |
| Particle Sizing Range | ~30–200 nm (diameter) |
| Capture Flexibility | Compatible with anti-VSV-G, anti-gp70, or user-provided custom capture antibodies |
| Nucleic Acid Detection | RNA-specific fluorescent probes (e.g., Quasar 670-labeled oligos) |
| Structural Discrimination | Simultaneous detection of capsid protein (e.g., p24), envelope glycoprotein (e.g., VSV-G), and genomic RNA |
| Aggregation Assessment | Quantitative resolution of monodisperse virions vs. dimers, trimers, and higher-order aggregates |
| Regulatory Alignment | Designed to support process development under ICH Q5A(R2), USP <1043>, and FDA CMC guidance for gene therapy products |
| Brand | Unchained Labs |
|---|---|
| Origin | Belgium |
| Manufacturer Type | Original Equipment Manufacturer (OEM) |
| Import Status | Imported |
| Model | Lunatic |
| Detection Time | 10 min per 96-well plate |
| Wavelength Accuracy | ±1 nm at ≤400 nm |
| BSA Detection Range | 0.02–275 mg/mL |
| DNA Detection Range | 1.5–13,750 ng/μL |
| Sample Types | Proteins, DNA, RNA, ssDNA, dsDNA, oligonucleotides |
| Sample Volume | 2 µL per well |
| Cuvette-Free Microfluidic Sample Handling | Yes |
| Plate Format | SBS-compliant 96-well microplate |
| Instrument Category | UV-Vis Microvolume Spectrophotometer for Biomolecular Quantification |
| Brand | Unchained Labs |
|---|---|
| Origin | Belgium |
| Manufacturer Type | Original Equipment Manufacturer (OEM) |
| Product Origin | Imported |
| Model | Sunscreen |
| Carrier Type | Lipid Nanoparticle (LNP) |
| Flow Rate Range | 0.1–30 mL/min |
| Maximum Flow Ratio | 5:1 |
| Sample Volume per Well | 400 µL – 2 mL |
| Brand | Unchained Labs |
|---|---|
| Origin | Belgium |
| Manufacturer Type | Manufacturer |
| Origin Category | Imported |
| Model | Uncle |
| Instrument Principle | Differential Scanning Fluorescence (DSF) |
| Measured Parameters | Tm, Tagg, Tonset, Isothermal Stability, Viral Capsid Stability, Viral Genome Release Temperature, Dye-based Tm (DSF), Hydrodynamic Size & Polydispersity Index (PDI), Tsize, Tagg660, Thermal Refolding Assay, Viscosity, kD, B22, G22, ΔG |
| Sample Volume | 9 µL |
| Protein Concentration Range | 0.05–300 mg/mL |
| Temperature Control Range | 15–95 °C |
| Sample Capacity | 48 samples |
| Sample Introduction Method | Quartz Capillaries |
| 21 CFR Part 11 Compliance | Yes |
| Dimensions | 54 cm × 50 cm × 58 cm |