Protein Stability Analyzer
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| Brand | Wyatt |
|---|---|
| Origin | USA |
| Manufacturer | Wyatt Technology Corporation |
| Type | Plate Reader III |
| Key | DLS & SLS Integration |
| Sample Throughput | 96-well and 384-well microplates |
| Detection Modes | Dynamic Light Scattering (DLS), Static Light Scattering (SLS), Temperature Ramp & Hold |
| Measurable Parameters | Hydrodynamic Radius (Rh), Radius of Gyration (Rg), Molecular Weight (Mw), Aggregation Onset Temperature (Tonset), Melting Temperature (Tm), Aggregation Temperature (Tagg), Diffusion Interaction Parameter (kD), Second Virial Coefficient (A2), B22, Turbidity, Viscosity (relative), Conformational Stability Index, Isothermal/Variable-Temperature Stability Profiles |
| Compliance | ASTM E2490, ISO 22412, USP <788>, FDA 21 CFR Part 11 Ready (with optional audit trail module) |
| Software Platform | Dynamics v8.x with GLP/GMP-compliant data handling |
| Brand | NanoTemper |
|---|---|
| Origin | Germany |
| Model | PR Panta |
| Temperature Control Range | 15 °C–95 °C (upgradeable to 110 °C with High-Temp Module) |
| Sample Volume | 10 μL |
| Sample Introduction | Capillary or capillary array |
| Dimensions | 35 cm (L) × 51 cm (H) × 52 cm (W) |
| Brand | NanoTemper |
|---|---|
| Origin | Germany |
| Manufacturer Type | Authorized Distributor |
| Product Category | Imported Instrument |
| Model | PR Panta Plus Robotic Autosample |
| Principle | Microfluidic Capillary Electrophoresis Coupled with Intrinsic Tryptophan Fluorescence Detection (not DLS — correction based on official NanoTemper documentation) |
| Temperature Control Range | 15 °C to 110 °C |
| Sample Volume | 10 µL per capillary |
| Sample Format | Disposable fused-silica capillaries (pre-filled or user-loaded) |
| 21 CFR Part 11 Compliance | Yes |
| Dimensions | 110 cm (W) × 188 cm (H) × 90 cm (D) |
| Brand | NanoTemper |
|---|---|
| Origin | Germany |
| Manufacturer | NanoTemper Technologies GmbH |
| Product Type | Imported Instrument |
| Model | Prometheus oDSF |
| Principle | Differential Scanning Fluorimetry (oDSF) |
| Sample Volume | 10 µL |
| Temperature Control Range | 15–110 °C |
| Sample Loading | Single capillary or capillary array |
| Dimensions | 35 cm (W) × 51 cm (H) × 52 cm (D) |
| Brand | NanoTemper |
|---|---|
| Origin | Germany |
| Manufacturer | NanoTemper Technologies GmbH |
| Product Type | Imported Instrument |
| Model | oDSF Prometheus Panta |
| Principle | Orthogonal Differential Scanning Fluorimetry (oDSF), Dynamic Light Scattering (DLS), Static Light Scattering (SLS), Backreflection Detection |
| Sample Volume | 10 µL |
| Temperature Control Range | 15–110 °C |
| Sample Format | Single capillary or capillary array |
| Dimensions | 35 cm (W) × 51 cm (H) × 52 cm (D) |
| Brand | NanoTemper |
|---|---|
| Origin | Germany |
| Manufacturer Type | Original Equipment Manufacturer (OEM) |
| Product Category | Imported Instrument |
| Model | Panta+Robotic Autosampler |
| Measurement Principle | Orthogonal Differential Scanning Fluorescence (oDSF) |
| Sample Volume | 10 µL |
| Temperature Control Range | 15–110 °C |
| Sample Capacity | 64 sample groups per run (1536 samples total before reload |
| Sample Loading Method | Capillary-based loading |
| Dimensions | 110 cm (W) × 188 cm (H) × 90 cm (D) |
| Brand | Thermo Fisher Scientific |
|---|---|
| Origin | USA |
| Model | 23246 |
| Format | Ready-to-use liquid reagent |
| Detection Wavelength | 595 nm |
| Sample Volume | 10 µL (microplate format) |
| Incubation Time | 10 min at room temperature |
| Linear Range | 2–1500 µg/mL (with 1% Triton X-100 or NP-40) |
| Compatibility | Compatible with ≥1% nonionic detergents including Triton X-100, NP-40, Tween-20, and CHAPS |
| Standard Curve Required | Yes (BSA-based, supplied separately or user-prepared) |
| Measurement Platform | UV-Vis spectrophotometer or microplate reader |
| Brand | Unchained Labs |
|---|---|
| Origin | Belgium |
| Manufacturer Type | Manufacturer |
| Origin Category | Imported |
| Model | Uncle |
| Instrument Principle | Differential Scanning Fluorescence (DSF) |
| Measured Parameters | Tm, Tagg, Tonset, Isothermal Stability, Viral Capsid Stability, Viral Genome Release Temperature, Dye-based Tm (DSF), Hydrodynamic Size & Polydispersity Index (PDI), Tsize, Tagg660, Thermal Refolding Assay, Viscosity, kD, B22, G22, ΔG |
| Sample Volume | 9 µL |
| Protein Concentration Range | 0.05–300 mg/mL |
| Temperature Control Range | 15–95 °C |
| Sample Capacity | 48 samples |
| Sample Introduction Method | Quartz Capillaries |
| 21 CFR Part 11 Compliance | Yes |
| Dimensions | 54 cm × 50 cm × 58 cm |