Cell Disruptor
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| Brand | Aitesen |
|---|---|
| Origin | Jiangsu, China |
| Model | HPH-L2 |
| Maximum Pressure | 2000 bar |
| Maximum Feed Particle Size | 500 µm |
| Flow Rate | 5–15 L/h |
| Minimum Sample Volume | 15 mL |
| Noise Level | 65 dB |
| Power | 1.5 kW |
| Dimensions (L×W×H) | 545 × 755 × 494 mm |
| Weight | 140 kg |
| Material | SAF2507 duplex stainless steel |
| Homogenization Valve | High-efficiency safety valve with manual pressure adjustment |
| Control Interface | Touchscreen panel with real-time pressure display, data logging, export capability, and programmable safety cutoff |
| Compliance | Manufactured per EU Machinery Directive 98/37/EC (MD) |
| Brand | Aitesen |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Product Category | Domestic |
| Model | HPH-L2 |
| Instrument Type | High-Pressure Cell Disruptor |
| Compliance | EU Machinery Directive 98/37/EC (MD) |
| Max Inlet Particle Size | 500 µm |
| Flow Rate | 5–15 L/h |
| Max Operating Pressure | 2000 bar |
| Minimum Sample Volume | 15 mL |
| Noise Level | 65 dB(A) |
| Power Rating | 1.5 kW |
| Cleaning & Sterilization | Yes |
| Dimensions (W×D×H) | 545 × 755 × 494 mm |
| Weight | 140 kg |
| Brand | Aitesen |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Product Origin | Domestic (China) |
| Model | HPH-L2 |
| Max. Pressure | 2000 bar |
| Max. Inlet Particle Size | 500 µm |
| Flow Rate | 5–15 L/h |
| Minimum Sample Volume | 15 mL |
| Noise Level | 65 dB(A) |
| Power | 1.5 kW |
| Dimensions (W×D×H) | 545 × 755 × 494 mm |
| Weight | 140 kg |
| Material | SAF2507 super duplex stainless steel |
| Compliance | EU Machinery Directive 98/37/EC (MD) |
| Cleaning & Sterilization | CIP-compatible, autoclavable components |
| Brand | Aitesen |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Product Category | Domestic |
| Model | HPH-L3 |
| Max. Inlet Particle Size | 500 µm |
| Flow Rate | 10–40 L/h |
| Max. Operating Pressure | 1800 bar |
| Minimum Sample Volume | 30 mL |
| Noise Level | 65 dB(A) |
| Power Rating | 5.5 kW |
| Cleaning & Sterilization | Yes |
| Dimensions (L×W×H) | 658 × 868 × 920 mm |
| Weight | 280 kg |
| Brand | Aitesen |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Product Category | Domestic |
| Model | HPH-L3 |
| Instrument Type | High-Pressure Cell Disruptor |
| Max. Inlet Particle Size | 500 µm |
| Flow Rate | 10–40 L/h |
| Max. Operating Pressure | 1800 bar |
| Minimum Sample Volume | 30 mL |
| Noise Level | 65 dB(A) |
| Power Rating | 5.5 kW |
| Cleaning & Sterilization | Yes |
| Dimensions (W×D×H) | 658 × 868 × 920 mm |
| Weight | 280 kg |
| Brand | Aitesen |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Product Category | Domestic |
| Model | HPH-L3 |
| Max. Inlet Particle Size | 500 µm |
| Flow Rate | 10–40 L/h |
| Max. Operating Pressure | 1800 bar |
| Minimum Sample Volume | 30 mL |
| Noise Level | 65 dB(A) |
| Power Rating | 5.5 kW |
| Dimensions (L×W×H) | 658 × 868 × 920 mm |
| Weight | 280 kg |
| Construction Material | SAF2507 Super Duplex Stainless Steel |
| Compliance | EU Machinery Directive 98/37/EC (MD) |
| Brand | Aitesen |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Country of Origin | China |
| Model | HPH-P Series |
| Instrument Type | High-Pressure Cell Disruptor |
| Flow Rate | 80–2000 L/h |
| Operating Pressure | 800–1500 bar |
| Construction Material | SAF2507 Super Duplex Stainless Steel |
| Control Interface | Touchscreen Panel with Real-Time Pressure Monitoring & Data Export Capability |
| Optional Systems | Variable-Frequency Flow Control, Automated Pressurization, PLC Integration, Temperature Control, Multi-Stage Homogenization, Closed-Loop Circulation, Sample Preconditioning Module |
| Brand | Aitesen |
|---|---|
| Origin | Jiangsu, China |
| Model | HPH-P1 |
| Construction | Modular pump head |
| Wetted materials | SAF2507 super duplex stainless steel |
| Homogenization valve | High-efficiency, safety-engineered |
| Pressure regulation | Manual handwheel + optional pneumatic actuation |
| Drive system | Stable, continuous-duty motor |
| Control interface | Touchscreen panel with real-time pressure monitoring, data logging, export capability (CSV), and programmable safety pressure limits |
| Optional modules | Variable-frequency flow control, automated pressurization, PLC-based automation, jacketed temperature control, multi-stage homogenization, closed-loop recirculation, and integrated sample preconditioning |
| Flow rate range | 80–2000 L/h |
| Maximum operating pressure | 1500 bar (standard configurations) |
| Application scope | Cell disruption (E. coli, yeast, mammalian cells), liposome & LNP formulation, fat emulsion processing, nanostructured material dispersion (CNTs, graphene, nanocellulose), sterile pharmaceutical final fill support |
| Brand | Aitesen |
|---|---|
| Origin | Jiangsu, China |
| Model | HPH-P1 |
| Construction | Split-head pump design |
| Wetted Materials | SAF2507 super duplex stainless steel |
| Homogenization Valve | High-efficiency safety valve with precision pressure control |
| Drive System | Stable high-torque motor assembly |
| Control Interface | Touchscreen panel with real-time pressure monitoring and data logging |
| Pressure Regulation | Manual and pneumatic dual-mode adjustment |
| Safety Features | Programmable pressure limit with audible/visual alarm |
| Optional Modules | Variable-frequency flow control, auto-pressurization system, PLC-based automation, jacketed temperature control, multi-stage homogenization, closed-loop recirculation, pre-conditioning unit |
| Flow Rate Range | 80–2000 L/h |
| Maximum Operating Pressure | 1500 bar (standard), 1000 bar (high-flow variants) |
| Compliance | Designed to support GLP/GMP-aligned workflows |
| Brand | ATS |
|---|---|
| Origin | Canada |
| Manufacturer Type | Original Equipment Manufacturer (OEM) |
| Product Category | Imported Instrument |
| Model | AH-1500 |
| Instrument Type | High-Pressure Cell Disruptor |
| Max Operating Pressure | 1500 bar (22,500 psi) |
| Optional Overpressure Capability | 1800 bar (27,000 psi) |
| Flow Rate | 15 L/h |
| Minimum Sample Volume | 25 mL |
| In-Line Cooling System | Integrated, maintains sample temperature < 20 °C |
| Contact Wetted Materials | ASTM A240 316L stainless steel |
| Motor Power | 2.2 kW, 380 V / 50 Hz |
| Weight | 110 kg |
| Compliance | CE-marked, GMP-compliant design |
| Particle Size Output | < 100 nm (after single-pass homogenization) |
| Disruption Efficiency | >95% for *E. coli*, >90% for yeast |
| Brand | ATS |
|---|---|
| Origin | Canada |
| Model | AH-1500 |
| Instrument Type | High-Pressure Cell Disruptor |
| Operating Pressure | 1500 bar (22,500 psi), up to 1800 bar (27,000 psi) |
| Motor Power | 2.2 kW, 380 V / 50 Hz |
| Throughput | 15 L/h |
| Minimum Sample Volume | 25 mL |
| In-Line Cooling System | Integrated, maintains sample temperature < 20 °C |
| Wetted Materials | 316L stainless steel |
| Compliance | CE-certified, GMP-compliant design |
| Particle Size Reduction | < 100 nm |
| Cell Disruption Efficiency | >95% for E. coli, >90% for yeast |
| Weight | 110 kg |
| Brand | ATS |
|---|---|
| Origin | Canada |
| Manufacturer | ATS (Original Equipment Manufacturer) |
| Product Type | Imported |
| Model | H10 |
| Instrument Category | High-Shear Cell Disruptor |
| Motor | German-sourced, industrial-grade |
| Bearing | SKF |
| Power | 0.5 kW |
| Voltage | 220 V, 50 Hz |
| Speed Range | 10,000–28,000 rpm (7-step infinitely variable control) |
| Tip Linear Velocity | up to 28.5 m/s |
| Net Weight | 9 kg |
| Batch Volume | 100–5,000 mL (tested in water |
| Protection Rating | IP55 |
| Insulation Class | F |
| Explosion-Proof | No |
| Rotor/Stator Material | Stainless Steel SUS304 or optional SUS316L |
| Brand | AVESTIN |
|---|---|
| Origin | Canada |
| Manufacturer | Avestin Inc., Ottawa, Canada |
| Model | EmulsiFlex-C50 |
| Max Operating Pressure | 30,000 psi (207 MPa) |
| Flow Rate | 15–50 L/h |
| Minimum Sample Volume | 25 mL |
| Drive Type | Pneumatic Dual-Piston |
| Safety | Auto-circuit cutoff with 20% transient overpressure tolerance |
| Construction Material | ASTM-certified 316L stainless steel |
| Sterilization | Direct steam-in-place (SIP), O-ring-free fluid path |
| Compliance | FDA 21 CFR Part 11-ready architecture, GMP-compliant design |
| Optional Accessories | Extrusion filter, heat exchanger |
| Instrument Category | High-Pressure Cell Disruptor |
| Brand | Avestin |
|---|---|
| Origin | Canada |
| Manufacturer | Avestin Inc., Ottawa, Canada |
| Model | EmulsiFlex-C55 |
| Pressure Range | 0–30,000 psi (0–207 MPa) |
| Flow Rate | 15–50 L/h |
| Minimum Sample Volume | 7 mL |
| Drive Type | Pneumatic Dual-Piston |
| Compliance | GMP, FDA 21 CFR Part 11–ready architecture, ASME BPE–compatible materials |
| Construction Material | Electropolished 316L stainless steel |
| Sterilization | SIP/CIP-capable, O-ring–free fluid path |
| Safety | Auto-cutoff circuit protection, transient overpressure tolerance up to 20% |
| Brand | Avestin |
|---|---|
| Origin | Canada |
| Manufacturer | Avestin Inc., Ottawa, ON |
| Model | EmulsiFlex-D20 |
| Operating Pressure | 35,000 psi (2,413 bar) / Max Continuous: 30,000 psi (2,070 bar) |
| Flow Rate | 20 L/h |
| Minimum Sample Volume | 50 mL |
| Sample Hold-up Volume | <1 mL |
| Drive Type | Electric Single-Plunger Pump |
| Dimensions (W×D×H) | 730 × 600 × 640 mm |
| Weight | 120 kg |
| Power Supply | 3-phase, 50/60 Hz, 230/400 V |
| Construction Material | ASTM A240 316L stainless steel + ceramic wear components |
| Sterilization | Direct steam-in-place (SIP) compatible |
| Compliance | GMP-compliant design, FDA 21 CFR Part 11–ready software architecture, USP <1043> and ISO 22442-1 applicable for bioprocess equipment qualification |
| Brand | Branson |
|---|---|
| Origin | Mexico |
| Manufacturer Type | Authorized Distributor |
| Import Status | Imported |
| Model | SFX150 |
| Instrument Type | Ultrasonic Cell Disruptor |
| Maximum Output Power | 150 W |
| Operating Frequency | 40 kHz |
| Sample Volume Range | 0.1–150 mL |
| Pulse Duration Resolution | 0.01 s |
| Amplitude Adjustment Range | 10–100% |
| Programmable Methods | 20 user-defined protocols |
| Energy Control Range | 1–999,999 J |
| Time Control Range | 0.01 s to 99 h 59 min 59 s |
| Input Voltage | AC 200–240 V, 50/60 Hz |
| Standard Probe | 3 mm (1/8″) titanium alloy (Ti-7Al-4V) |
| Dimensions (W×D×H) | 348 × 203 × 242 mm |
| Weight | 6.35 kg |
| Brand | COMECAUSE |
|---|---|
| Origin | Shandong, China |
| Manufacturer Type | Direct Manufacturer |
| Instrument Type | Ultrasonic Cell Disruptor |
| Model | IN-FT300 |
| Operating Frequency | 20–25 kHz |
| Ultrasonic Power Output | 20–300 W |
| Sample Volume Capacity | 0.1–300 mL (with interchangeable titanium alloy probes) |
| Pulse Control Resolution | 0.1 s (on/off/total time) |
| Temperature Monitoring Range | 0–99.9 °C (contact-type sensor) |
| Display | 10.1″ HD capacitive touchscreen |
| Probe Material | TC4 titanium alloy |
| Transducer Housing | Aerospace-grade magnesium-aluminum alloy |
| Data Storage | 256 programmable protocols |
| Compliance | CE-marked design principles |
| Brand | DELEITE |
|---|---|
| Origin | Shanghai, China |
| Model | DLT-2400 |
| Instrument Type | Ultrasonic Cell Disruptor |
| Operating Frequency | 20 kHz ± 0.5 kHz |
| Ultrasonic Power Output | 2400 W (continuously adjustable from 1% to 100%) |
| Sample Volume Capacity | 500–2000 mL |
| Temperature Control Range | 0–99.9 °C |
| Duty Cycle Adjustment | 0.1–99.9% |
| Display | 7-inch TFT capacitive touchscreen |
| Probe Material | TC4 titanium alloy |
| Standard Horn Diameter | Φ25 mm (optional horns: Φ3, 6, 10, 15, 20, 22, 25, 28 mm) |
| Safety Features | Overcurrent, overvoltage, overtemperature, and timer fault protection |
| Cooling | Integrated NTC thermistor-based sample temperature monitoring |
| Configuration | Separated main unit + acoustic isolation chamber with motorized lift stage and LED illumination |
| Optional Upgrades | UV sterilization module |
| Brand | DLAB |
|---|---|
| Origin | Beijing, China |
| Model | MX-C |
| Temperature Range | 0–60 °C |
| Operating Frequency | 20–25 kHz |
| Ultrasonic Power Output | 0–300 W |
| Sample Volume per Tube | 0.5–50 mL |
| Throughput | 8 samples (max. 2 mL/tube) |
| Vortex Motion | Orbital shaking with 4 mm orbit diameter |
| Speed Range | 0–3000 rpm (adjustable) |
| Power Input | 60 W |
| Voltage | 100–120 V / 200–240 V, 50/60 Hz |
| Dimensions (L×W×H) | 127 × 130 × 160 mm |
| Weight | 2.0 kg |
| Brand | Hanuo |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Authorized Distributor |
| Product Category | Domestic |
| Model | HN-1200Y |
| Instrument Type | Ultrasonic Cell Disruptor |
| Ultrasonic Power Output | 1000 W (adjustable 1–100% duty cycle) |
| Operating Frequency Range | 19–23 kHz |
| Temperature Control Range | −5 °C to +100 °C |
| Maximum Sample Volume | 1000 mL |
| Single-Sample Processing Capacity | 1 unit per cycle |
| Standard Probe Diameter | Φ20 mm |
| Optional Probes | Φ10 mm, Φ15 mm, Φ22 mm |
| Brand | Hechuang |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Country of Origin | China |
| Model | HC-1500T |
| Instrument Type | Ultrasonic Cell Disruptor |
| Temperature Range | 0–120 °C |
| Operating Frequency | 25 kHz |
| Ultrasonic Power Output | 1500 W |
| Sample Volume Capacity | 0.2–2000 mL |
| Control Interface | 7-inch capacitive touchscreen |
| Pulse Mode | Adjustable from 0.1 s to 999.9 s (on/off) |
| Amplitude Compensation | Auto-compensated |
| Transducer Material | PZT ceramic (lead zirconate titanate) |
| Probe Material | ASTM-grade TC4 titanium alloy (Ti-6Al-4V) |
| Standard Probe Diameter | 15 mm (optional: 8/10/12/20 mm) |
| Integrated Cooling Compatibility | Yes |
| Enclosure | Powder-coated steel frame with polymer housing |
| Dimensions (W×D×H) | 350 × 300 × 500 mm |
| Built-in Stainless Steel Vertical Stage | Yes |
| Brand | Hechuang |
|---|---|
| Origin | Jiangsu, China |
| Manufacturer Type | Authorized Distributor |
| Country of Origin | China |
| Model | HC-2000E |
| Instrument Type | Ultrasonic Cell Disruptor |
| Temperature Range | 0–120 °C |
| Operating Frequency | 20–25 kHz |
| Ultrasonic Power Output | 2000 W |
| Sample Volume Capacity | 0.2–2000 mL |
| Control Interface | 7-inch capacitive touchscreen |
| Pulse Mode Timing | 0.1 s to 999 min (on/off cycles independently configurable) |
| Probe Material | ASTM F136 TC4 titanium alloy |
| Transducer | PZT-4 piezoelectric ceramic (CV33-grade) |
| Amplitude Adjustment | 0–100% continuous |
| Real-time Display | Amplitude %, frequency (Hz), cumulative operating time, temperature (if external probe connected) |
| Brand | Tianjin HengAo |
|---|---|
| Origin | Tianjin, China |
| Manufacturer Type | Direct Manufacturer |
| Instrument Type | Ultrasonic Cell Disruptor |
| Ultrasonic Power | 80 W (HPU-100) / 400 W (HPU-400A) |
| Operating Frequency | Adjustable |
| Temperature Range | 0–100 °C |
| Sample Volume | 150 µL (minimum) |
| Sample Capacity | Single sample per cycle |
| Pulse Duty Cycle | 1–99% (adjustable) |
| Timer Range | 1–99 min |
| Probe Options | 1/8″ (HPU-100), 1/2″ (HPU-400A) |
| Sample Volumes Supported | 1–100 mL (HPU-100) |
| Memory Presets | 5 user-defined protocols |
| Origin | USA |
|---|---|
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | M-700 Series |
| Instrument Type | High-Pressure Cell Disruptor |
| Max Operating Pressure | 40,000 psi |
| Max Flow Rate | 15.6 L/min |
| Inlet Temperature Range | Up to 75 °C |
| Power Supply | 3-Phase, 380 V, 15–50 HP |
| Air Supply | 50–150 psi, 1 SCFM @ 50 psi, Dew Point: 0–35 °F |
| Dimensions | 74 × 180 × 145 cm |
| Weight | 675–900 kg |
| Chamber Material | Diamond-Embedded Stainless Steel |
| Construction | Fully 316L Stainless Steel |
| Origin | USA |
|---|---|
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | M-110Y |
| Instrument Type | High-Pressure Cell Disruptor |
| Operating Pressure Range | 3,000–23,000 psi |
| Max. Flow Rate | 250–600 mL/min |
| Feed Temperature Range | –25°C to +75°C |
| Minimum Sample Volume | 14 mL |
| Compressed Air Requirement | 57 scfm at 120 psi, 15 hp (11 kW) |
| Dimensions | 28 × 41 × 76 cm |
| Weight | 25 kg |
| Interaction Chamber Material | Diamond or Ceramic |
| Wetted Parts | 300-series Stainless Steel (Chromium-Plated Piston) |
| Integrated Cooling Coil | 17 ft (13 mL volume) |
| Cleaning | CIP-capable (Clean-in-Place) |
| Certification | Explosion-Proof & Portable Design |
| Origin | USA |
|---|---|
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | M-110EH |
| Instrument Type | High-Pressure Cell Disruptor |
| Max Operating Pressure | 30,000 psi (207 MPa) |
| Max Flow Rate | 450 mL/min |
| Inlet Temp. Range | ≤75°C |
| Power Supply | 3-Phase, 380 V, 5 HP (3.7 kW) |
| Fluid Path Volume | 100 mL |
| Compressed Air Requirement | 35–150 psi |
| Dew Point | 0–35°F |
| Minimum Sample Volume | 120 mL |
| Dimensions | 73 × 87 × 148 cm |
| Weight | 205 kg |
| IXC Chamber Material | Synthetic Diamond |
| Regulatory Compliance | CE Certified |
| Cleaning | CIP-Compatible |
| Sterilization | SIP-Capable (Steam or Hot Water) |
| Origin | USA |
|---|---|
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | HC-8000 |
| Price Range | USD $14,000–$70,000 |
| Instrument Type | High-Pressure Cell Disruptor |
| Max Operating Pressure | 1,000–8,000 psi |
| Max Flow Rate | 1,000 mL/min |
| Feed Temperature Limit | 75 °C |
| Compressed Air Requirement | 57 SCFM at 50 psi, dew point −17.7 to 1.6 °C, 15 hp (11 kW) |
| Minimum Sample Volume | 250 mL |
| Dimensions | 58 × 38 × 58 cm |
| Weight | 26.7 kg |
| Construction Material | Electropolished 316 Stainless Steel |
| Cleaning | CIP-capable high-pressure fluid path |
| Drive Mechanism | Pneumatic, explosion-proof |
| Sterilization Compliance | Autoclavable and SIP-compatible components |
| Brand | Scientz |
|---|---|
| Origin | Zhejiang, China |
| Model | SCIENTZ-08-II |
| Instrument Type | Non-contact ultrasonic cell disruptor (cup-horn system) |
| Operating Frequency | 40 kHz |
| Adjustable Ultrasonic Power | 1800 W |
| Sample Volume Range | 5 µL – 15 mL |
| Sample Capacity | 1–16 tubes |
| Power Adjustment Range | 1–99% |
| Timer Range | 1–999 min |
| Duty Cycle | 0.1–99.9% |
| Tank Volume | 1.5 L |
| Compatible Vessel Formats | 1–2 mL × 16 wells, 5 mL × 8 wells, 10–15 mL × 8 wells |
| Temperature Monitoring | Yes |
| Input Voltage | 220/110 V ±0.5%, 50/60 Hz |
| Brand | Qsonica LLC |
|---|---|
| Country of Origin | USA |
| Model | Q700 |
| Instrument Type | Ultrasonic Cell Disruptor |
| Ultrasonic Power Output | 700 W |
| Operating Frequency | 20 kHz |
| Temperature Range | 1–121 °C |
| Sample Volume Capacity | 5 µL – 1000 L (via flow cell or microtip) |
| Throughput | 1–384 samples per run |
| Compliance | UL, CE, CSA, RoHS |
| Brand | Scientz |
|---|---|
| Origin | Zhejiang, China |
| Model | CFU-750W-M1 |
| Instrument Type | Ultrasonic Cell Disruptor |
| Operating Frequency | 20 kHz ± 1 kHz |
| Ultrasonic Power Output | 750 W |
| Temperature Control Range | −30 °C to 100 °C |
| Sample Throughput | 1–50 L/h |
| Reactor Material | SUS316 Stainless Steel |
| Transducer & Horn Material | Titanium Alloy (Grade 5) |
| Control Interface | 10-inch Capacitive Touchscreen |
| Data Logging | Internal storage with USB export |
| Communication Protocol | Modbus-TCP over RJ45 Ethernet |
| User Access Control | Three-tier permission system (Admin / Operator / Guest) |
| Sterilization Compatibility | In-situ steam sterilization (SIP) or offline autoclaving (121 °C, 2 bar, 30 min) |
| Cooling Architecture | Double-jacketed reactor with external chiller integration (e.g., DC-3006) |