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| Brand | AB SCIEX |
|---|---|
| Origin | USA |
| Model | TripleTOF 6600 |
| Instrument Type | Quadrupole-Time-of-Flight (Q-TOF) |
| Resolution | 30,000 (FWHM at m/z 1,000) |
| Sensitivity | 10.1 fmol (substance P, S/N ≥ 10) |
| Mass Accuracy | < 100 ppm (internal calibration), < 5 ppm (external calibration with lock mass) |
| Stability | ≤ 10 ppm RMS over 24 h |
| Acquisition Rate | 50 Hz (MS/MS spectra per second) |
| SWATH™ Acquisition | Up to 200 variable isolation windows per cycle |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Instrument Type | Time-of-Flight (TOF) Hybrid Quadrupole-TOF Mass Spectrometer |
| Model | TripleTOF 6600 |
| Resolution | 10,000 (FWHM at m/z 956) |
| Sensitivity | ≤10 amol β-galactosidase tryptic peptide (S/N ≥10) |
| Mass Accuracy | ≤10 ppm RMS (calibrated) |
| Mass Stability | ≤10 ppm over 24 h |
| Acquisition Rate | Up to 100 Hz MS/MS spectra |
| Linear Dynamic Range | 5 orders of magnitude |
| Q1 m/z Range | Up to 2250 Th |
| SWATH Window Flexibility | 2–25 Da variable width, up to 200 windows per cycle |
| Brand | Thermo Fisher |
|---|---|
| Origin | USA |
| Instrument Type | Orbitrap Tribrid |
| Model | Fusion Lumos |
| Resolution | 30,000 (at m/z 200, MS1) |
| Mass Accuracy | ≤10 ppm (internal calibration) |
| Sensitivity | 10.1 (fmol-level S/N for standard peptides) |
| Stability | ≤10 ppm RMS mass drift over 24 h |
| Acquisition Rate | 50 Hz (MS/MS in parallel mode) |
| Mass Range | m/z 50–6,000 |
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