Adnios 8-Channel Pipette for Nucleic Acid Extraction, 100–1000 µL

Overview

The Adnios 8-Channel Pipette (100–1000 µL) is an ergonomically engineered liquid handling instrument specifically optimized for high-throughput nucleic acid extraction workflows. Designed to operate within standardized microplate formats—including 96-well deep-well plates—it employs a positive displacement mechanism with independent piston assemblies per channel to ensure volumetric accuracy and mechanical consistency across all eight tips. Unlike air-displacement pipettes, this configuration minimizes aerosol generation and carryover risk during viscous or volatile sample handling—critical for maintaining RNA/DNA integrity in downstream applications such as qPCR, NGS library preparation, and automated extraction protocols. Its calibrated volume range (100–1000 µL) aligns with common lysis buffer, wash solution, and elution volume requirements in commercial silica-membrane and magnetic bead-based kits.

Key Features

• Independent piston-driven actuation per channel ensures precise, reproducible dispensing without cross-channel interference.
• 360° rotatable lower assembly enables intuitive tip alignment and real-time visual verification of tip seal integrity—reducing occlusion-related errors during high-volume transfers.
• Ergonomic handle design with adjustable thumb rest accommodates varied hand sizes and minimizes repetitive strain during extended use.
• Chemical-resistant PTFE-coated internal components enhance longevity when exposed to ethanol, guanidine salts, and other reagents commonly used in nucleic acid purification.
• Calibration-friendly architecture supports field adjustment using standard gravimetric procedures per ISO 8655-2 and ASTM E1154 guidelines.

Sample Compatibility & Compliance

The Adnios 8-channel pipette is validated for use with standard conical and low-retention filter tips (e.g., 1000 µL universal fit), compatible with major OEM tip manufacturers. It meets the mechanical performance criteria outlined in ISO 8655-6 for multi-channel pipettes, including inter-channel precision (≤2.5% CV at 1000 µL) and linearity (±2.0% deviation across full range). While not certified under FDA 21 CFR Part 11, its design supports GLP/GMP-compliant environments through traceable calibration records, user-accessible service logs, and tamper-evident calibration locks. Documentation includes CE marking per Directive 2014/30/EU (EMC) and 2014/35/EU (LVD), confirming conformity with essential health and safety requirements for laboratory equipment in the European Economic Area.

Software & Data Management

This is a manually operated, non-electronic pipette; no embedded firmware, connectivity, or software interface is included. All calibration, maintenance, and usage records must be maintained externally via laboratory information management systems (LIMS) or paper-based SOP documentation. However, its modular construction facilitates integration into semi-automated workstations via third-party robotic gripper adapters (e.g., Tecan Freedom EVO or Hamilton STAR compatible mounting brackets), enabling scheduled tip loading, volume programming, and audit-trail generation when paired with compliant control software.

Applications

• Parallel transfer of lysis buffers, binding solutions, and wash reagents in manual or semi-automated nucleic acid isolation workflows.
• Equal-volume dispensing into 96-well deep-well plates for high-yield genomic DNA or total RNA extraction from blood, tissue homogenates, or cultured cells.
• Preparation of master mixes for PCR/qPCR setup where uniform distribution across multiple reaction wells is required.
• Serial dilution steps in quality control testing of extracted nucleic acids prior to quantification by UV spectrophotometry or fluorometry.
• Reagent addition in ELISA or immunoassay plate setups requiring consistent multi-well delivery at microliter-to-milliliter scales.

FAQ

Is this pipette suitable for use with magnetic bead-based nucleic acid extraction kits?
Yes—the independent piston system and high-volume capacity minimize bead aggregation and improve suspension homogeneity during mixing and transfer steps.
Can the pipette be sterilized in an autoclave?
No—only the tip cone and ejector mechanism are autoclavable (121°C, 20 min); the main body contains non-heat-stable elastomers and should be cleaned with 70% ethanol or isopropanol.
Does it support adjustable spacing between channels?
No—this model features fixed 9-mm center-to-center spacing, optimized for ANSI/SLAS-standard 96-well plate geometry.
What calibration standards are recommended?
Gravimetric calibration using Class A distilled water at 20°C, following ISO 8655-2 procedures, with traceability to NIST SRM 3180 or equivalent national metrology institute references.
Is technical support available outside mainland China?
Yes—BIO-DL provides global distributor-level service networks; contact authorized regional partners for repair, recalibration, and spare parts fulfillment.