Anyan AYAN-10L Membrane-Based High-Purity Nitrogen Generator

Overview

The Anyan AYAN-10L is a compact, membrane-based nitrogen generator engineered for continuous, on-demand supply of high-purity nitrogen gas (99% N₂) at up to 10 L/min and 0.8 MPa. It employs polymer membrane separation technology—leveraging differential permeability of oxygen, water vapor, and nitrogen across hollow-fiber membranes under controlled pressure—to separate nitrogen from compressed ambient air. Unlike pressure swing adsorption (PSA) systems, the AYAN-10L eliminates moving valves, adsorbent beds, and regeneration cycles, resulting in silent operation, rapid start-up (≤3 minutes), and minimal maintenance. Designed specifically for laboratory environments where space, safety, and operational continuity are critical, it replaces high-pressure nitrogen cylinders in applications requiring moderate purity and high volumetric flow—such as nitrogen blow-down (N₂ evaporation) in sample preparation, LC-MS ion source gas supply, inert atmosphere purging, and GC carrier gas backup.

Key Features

• Fully automated operation with integrated PLC control—no manual intervention required during normal operation.
• Digital front-panel display showing real-time nitrogen flow rate, system pressure, and operational status indicators.
• Three-stage pre-filtration system (coalescing filter, activated carbon adsorber, and ultra-fine particulate filter) ensures removal of oil aerosols, hydrocarbons, moisture, and particles down to 0.01 µm before air enters the membrane module.
• Integrated stainless-steel buffer tank with pressure stabilization and ISO 4126-1 certified safety relief valve for overpressure protection.
• Modular, space-efficient architecture (500 × 330 × 710 mm) optimized for benchtop or floor-standing deployment; fitted with industrial-grade locking casters for repositioning within shared lab spaces.
• Self-diagnostic firmware continuously monitors membrane inlet pressure, temperature, and flow consistency—triggering visual alerts and context-sensitive service prompts upon deviation from nominal operating windows.
• No consumable adsorbents or periodic replacement cartridges; membrane lifetime exceeds 15,000 hours under specified inlet air quality (ISO 8573-1 Class 3:2:2).

Sample Compatibility & Compliance

The AYAN-10L is compatible with standard laboratory nitrogen-dependent instrumentation including but not limited to nitrogen evaporators (e.g., Techne DB-3, Organomation N-EVAP), LC-MS ion sources (e.g., Waters Xevo TQ-S, Thermo Scientific Q Exactive), and preparative SPE/GPC systems. It meets ISO 8573-1:2010 air quality requirements when paired with recommended inlet filtration. While not certified to FDA 21 CFR Part 11 or EU Annex 11 out-of-the-box, its deterministic control logic, non-volatile event logging (via optional RS-485/Modbus interface), and audit-ready operational history support integration into GLP- and GMP-aligned workflows where instrument qualification (IQ/OQ/PQ) is performed per internal SOPs. The unit complies with CE electromagnetic compatibility (EMC) Directive 2014/30/EU and Low Voltage Directive 2014/35/EU.

Software & Data Management

The AYAN-10L operates via embedded microcontroller firmware without external software dependency. All operational parameters—including cumulative runtime, total nitrogen volume delivered, and fault log timestamps—are stored in non-volatile memory and accessible through the front-panel interface. Optional RS-485 serial output enables integration with building management systems (BMS) or centralized lab monitoring platforms using Modbus RTU protocol. Raw data export (CSV-formatted) is supported via USB-to-serial adapter for trend analysis in Excel or LabArchives. No cloud connectivity or proprietary software installation is required—ensuring full data sovereignty and compatibility with air-gapped laboratory networks.

Applications

• Nitrogen blow-down for solvent evaporation in environmental, clinical, and food testing labs (e.g., EPA Method 525.3, AOAC 2007.01).
• LC-MS electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) auxiliary gas supply where 99% purity and ≥5 L/min flow are sufficient.
• Inert blanketing during sample storage, reagent handling, and lyophilization pre-chamber conditioning.
• Carrier gas backup for GC systems during cylinder changeover (not suitable for primary carrier gas in high-resolution GC-MS due to purity limitations).
• Automated solid-phase extraction (SPE) manifold purge and elution steps requiring stable, oil-free nitrogen at variable flow rates.

FAQ

What inlet air quality is required for optimal membrane performance?
Compressed air must meet ISO 8573-1 Class 3:2:2 specifications—maximum 5 µm particulates, ≤0.1 mg/m³ oil content, and dew point ≤−40 °C. Use of an appropriately sized refrigerated dryer and coalescing filter upstream is mandatory.
Can the AYAN-10L be used as primary carrier gas for GC-MS?
No. GC-MS typically requires ≥99.99% nitrogen purity and ultra-low hydrocarbon/oxygen residuals. This unit delivers 99% N₂ and is intended for auxiliary or preparatory applications only.
Is the nitrogen output dry enough for moisture-sensitive applications?
Yes—the integrated filtration and membrane process yields nitrogen with dew point ≤−40 °C at 0.8 MPa, meeting ASTM D6644 for trace moisture control in most sample prep workflows.
How often does the membrane module require replacement?
Under compliant inlet air conditions, the membrane has a rated service life of ≥15,000 operational hours. Replacement is only necessary if flow rate drops >15% at nominal pressure or purity falls below 98.5%—both monitored continuously by the onboard diagnostic system.
Does the unit support remote monitoring or alarm relay outputs?
Yes—optional dry-contact alarm relays (NO/NC) and Modbus RTU over RS-485 enable integration with facility SCADA or lab-wide alert systems. Configuration requires technician-level access via serial terminal.