Anyan AYAN-5LG Membrane-Based High-Purity Nitrogen Generator

Overview

The Anyan AYAN-5LG is a laboratory-grade membrane-based nitrogen generator engineered for continuous, on-demand production of high-purity nitrogen gas (99.9%) at a stable flow rate of 5 L/min and adjustable pressure up to 0.6 MPa. It employs hollow-fiber membrane separation technology—where compressed ambient air is passed through a bundle of asymmetric polymeric membranes. Due to differences in gas permeability and diffusion coefficients, oxygen, water vapor, CO₂, and other trace contaminants permeate the membrane wall more rapidly than nitrogen, resulting in a nitrogen-enriched product stream at the outlet. This physical separation process requires no consumables, chemical reagents, or regeneration cycles, delivering inherently stable output with minimal operator intervention. Designed for integration into analytical workflows—including LC-MS, GC carrier gas supply, sample preparation inerting, and instrument purge applications—the AYAN-5LG eliminates dependency on high-pressure nitrogen cylinders while maintaining consistent purity and flow under variable demand conditions.

Key Features

• Hollow-fiber membrane core with proven long-term stability—rated for ≥10,000 hours of continuous operation under clean, dry feed air conditions
• Integrated three-stage air purification system: coalescing filter (removes oil aerosols and particulates ≥0.01 µm), activated carbon adsorber (eliminates hydrocarbons and odors), and desiccant dryer (achieves −45 °C pressure dew point)
• Real-time digital flow and pressure monitoring via front-panel LED display; adjustable output pressure regulated by precision back-pressure valve
• Low-maintenance architecture: no electrolyte replenishment, no molecular sieve replacement, no scheduled catalyst servicing
• Compact footprint (500 × 330 × 710 mm) with rear-mounted nitrogen outlet compatible with standard 1/8″ Swagelok® or BSPP fittings
• Compliance-ready design: CE-marked electrical components; meets IEC 61000-6-3 (EMC emission) and IEC 61000-6-2 (immunity) standards

Sample Compatibility & Compliance

The AYAN-5LG delivers nitrogen meeting ISO 8573-1:2010 Class 2:2:2 specifications for compressed air quality—translated to ≤0.1 mg/m³ total oil content, ≤0.1 µm solid particles, and −45 °C pressure dew point—ensuring compatibility with sensitive instrumentation such as mass spectrometers and FTIR systems. While not certified to FDA 21 CFR Part 11 out-of-the-box, its analog control architecture supports external audit trail logging when integrated with validated laboratory information management systems (LIMS). The generated nitrogen complies with ASTM D6349–22 requirements for GC carrier gas purity (oxygen <10 ppm, moisture <1 ppm) when used with appropriate downstream polishing filters. No internal wet chemistry or alkaline electrolytes are employed, eliminating risk of caustic carryover—a critical advantage over electrochemical generators in regulated QC/QA environments operating under GLP or GMP guidelines.

Software & Data Management

The AYAN-5LG operates via embedded microcontroller logic without proprietary software dependencies. All operational parameters—including inlet pressure, outlet flow, and system status—are displayed locally via dual 4-digit LED readouts. For laboratories requiring data capture, an optional RS-485 Modbus RTU interface (model AYAN-5LG-MB) enables integration with SCADA platforms or custom Python/Node-RED scripts for time-stamped logging of flow and pressure trends. Audit trails can be generated externally via timestamped serial logs, supporting retrospective review per ALCOA+ principles. Firmware updates are performed via physical USB port using signed binary packages—no cloud connectivity or remote access capabilities are implemented, preserving network security integrity in air-gapped lab environments.

Applications

• GC carrier and detector make-up gas for FID, TCD, and ECD systems requiring ≥99.9% N₂ with low oxygen and moisture residuals
• LC-MS nitrogen nebulizer and drying gas supply, where consistent dew point control prevents source contamination
• Inert atmosphere generation for glove boxes, solvent evaporation stations, and sample storage cabinets
• Blanketing and purging during synthesis, crystallization, or lyophilization protocols demanding reproducible O₂ exclusion
• Calibration gas dilution systems requiring stable, metered nitrogen background streams
• Supporting ISO/IEC 17025-accredited testing labs seeking documented, traceable gas sourcing alternatives to cylinder-based supply chains

FAQ

What feed air quality is required for optimal membrane performance?
The generator requires oil-free, cooled, and desiccated compressed air meeting ISO 8573-1 Class 1:4:3 (≤0.01 mg/m³ oil, ≤5 µm particles, −20 °C pressure dew point) prior to entry. Use of a refrigerated dryer upstream of the AYAN-5LG is strongly recommended.
Can output purity be increased beyond 99.9%?
No—membrane separation inherently limits maximum purity to ~99.95% under ideal conditions. For >99.99% N₂, PSA-based systems (e.g., Anyan AYAN-5PSA) are recommended.
Is routine maintenance required?
Yes—pre-filter elements should be replaced every 6 months under continuous operation; desiccant media requires replacement annually or after 2000 hours of use, whichever occurs first.
Does the unit support uninterrupted operation during power cycling?
Yes—the internal pressure-hold circuit maintains nitrogen pressure for up to 90 seconds during brief interruptions, preventing flow collapse in connected instruments.
What safety certifications does the AYAN-5LG hold?
It carries CE marking per Machinery Directive 2006/42/EC and Low Voltage Directive 2014/35/EU; full test reports available upon request for institutional procurement review.