AYAN-F80-S Stainless Steel Short-Path Molecular Distillation Unit
| Brand | AYAN |
|---|---|
| Origin | Zhejiang, China |
| Manufacturer Type | Authorized Distributor |
| Country of Origin | China |
| Model | AYAN-F80-S |
| Feed Rate | 0.5–4.0 L/h |
| Effective Evaporation Area | 0.1 m² |
| Evaporator Internal Diameter | 80 mm |
| Condenser Surface Area | 0.15 m² |
| Compatible Collection Flask Capacity | 2 L |
Overview
The AYAN-F80-S Stainless Steel Short-Path Molecular Distillation Unit is a precision-engineered laboratory-scale purification system designed for high-efficiency separation of thermally sensitive, high-boiling-point, or low-volatility compounds under ultra-high vacuum conditions. Unlike conventional distillation—where separation relies on differences in boiling points—molecular distillation operates on the principle of mean free path differential: under pressures typically below 0.001 mbar, the average distance traveled by vapor molecules exceeds the physical gap between the evaporating surface and the condensing surface. This enables rapid, non-equilibrium vapor transport with minimal residence time and negligible thermal degradation. The unit integrates a vertically oriented stainless steel evaporator with an internal condenser, optimized for laminar film formation via a rotating wiper mechanism, ensuring uniform heat transfer and consistent molecular flux across the 0.1 m² active evaporation area.
Key Features
- Stainless steel construction (316L-grade contact surfaces) for chemical resistance, vacuum integrity, and compliance with GLP-compatible cleaning protocols.
- Motor-driven PTFE-coated wiper system ensuring stable, thin-film generation across the 80 mm internal diameter evaporator cylinder—even for viscous or polymer-containing feeds.
- Integrated cold trap and dual-stage vacuum system compatibility (typically requiring a primary scroll pump + secondary turbomolecular pump) to achieve operational pressures down to 1×10⁻³ mbar.
- Programmable digital temperature control for both heating mantle (up to 250 °C) and condenser jacket (down to −20 °C with external chiller), enabling precise thermal gradient management.
- Modular design supporting interchangeable 2 L collection flasks with standardized ISO-KF 25/35 vacuum ports, facilitating multi-fraction collection without system venting.
- Real-time monitoring of key process parameters—including vacuum level, feed temperature, evaporator wall temperature, and condenser surface temperature—via front-panel digital display and analog output interfaces.
Sample Compatibility & Compliance
The AYAN-F80-S accommodates a broad range of heat-labile and high-molecular-weight substances, including but not limited to: natural vitamin E acetate, fish oil omega-3 concentrates (EPA/DHA), phospholipids, terpenes, cannabinoid distillates, silicone oils, and specialty polymeric monomers. Its short-path geometry (evaporator-to-condenser distance < 50 mm) minimizes back-scattering and recombination losses, delivering high-purity distillates with reproducible cut points. The unit conforms to general laboratory safety standards per IEC 61010-1 and supports documentation workflows aligned with ISO/IEC 17025 quality requirements. While not pre-certified for GMP manufacturing, its traceable temperature/vacuum logging capability and stainless-steel wetted parts facilitate validation for pilot-scale process development under FDA 21 CFR Part 11–compliant data management systems (when integrated with compliant software).
Software & Data Management
The AYAN-F80-S operates as a standalone instrument with local parameter control; however, it provides 0–10 V analog outputs and RS485 Modbus RTU interface for integration into centralized lab automation platforms. When paired with third-party SCADA or LIMS-compatible acquisition software, users can archive time-stamped records of vacuum pressure, heater setpoint vs. actual, condenser temperature, and feed flow rate—enabling full audit trails required for method validation, regulatory submissions, or internal quality reviews. All firmware updates are performed via USB port using manufacturer-provided configuration tools, with version history retained in device memory.
Applications
- Purification of bioactive lipids from crude algal or krill oil extracts while preserving cis-unsaturated bond integrity.
- Deacidification and deodorization of edible-grade esters without hydrolysis or oxidative side reactions.
- Isolation of monoacylglycerides and diacylglycerides for pharmaceutical excipient qualification.
- Removal of residual solvents (e.g., hexane, toluene) from botanical extracts prior to analytical standard preparation.
- Preparative-scale fractionation of synthetic oligomers to narrow polydispersity index (PDI) windows for polymer characterization studies.
- Recovery and concentration of volatile aroma compounds from steam-distilled hydrosols under sub-ambient condensation conditions.
FAQ
What vacuum level is required for optimal operation?
The system is engineered for sustained operation at ≤1×10⁻³ mbar; performance verification requires calibration-grade capacitance manometer measurement—not mechanical gauges.
Can the unit handle feed streams containing suspended solids?
No. Feed solutions must be pre-filtered to ≤5 µm particle size to prevent wiper blade jamming or evaporator surface fouling.
Is fractional collection possible during a single run?
Yes—by sequential rotation of the collection manifold or manual flask switching under continuous vacuum, provided condenser temperature remains stable.
What maintenance intervals are recommended for the wiper assembly?
PTFE wiper blades should be inspected after every 200 operating hours and replaced if edge wear exceeds 0.3 mm radial deviation.
Does the system include vacuum pump and chiller?
No. These are specified as optional ancillary components; pump selection must match ultimate pressure and gas load requirements of the target application.
