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BIO-DL e-HC Electric Large-Volume Pipette

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Brand BIO-DL
Origin Shanghai, China
Manufacturer Type Authorized Distributor
Country of Origin China
Model e-HC Electric Large-Volume Pipette
Pricing Available Upon Request

Overview

The BIO-DL e-HC Electric Large-Volume Pipette is an ergonomically engineered liquid handling instrument designed for precise, repeatable, and fatigue-free aspiration and dispensing of volumes ranging from 0.1 mL to 100 mL. Unlike manual or semi-automated pipettes, the e-HC employs a brushless DC motor coupled with a high-torque transmission system to deliver consistent piston-driven displacement across its full volume range. Its operational principle relies on positive displacement via calibrated air displacement within a sealed, pressure-balanced chamber—ensuring minimal aerosol generation and high volumetric accuracy even with viscous, volatile, or temperature-sensitive media such as cell culture media, serum supplements, and buffered saline solutions. The device is optimized for high-throughput workflows in cell biology, bioprocessing, and quality control laboratories where reproducible large-volume transfers are critical to assay integrity and operator safety.

Key Features

  • Ergonomic handheld design with balanced weight distribution and soft-grip surface texture to reduce wrist strain during extended use.
  • Three-tier tactile speed control (Low/Medium/High) accessible via responsive capacitive touch interface—enabling real-time adjustment of aspiration and dispensing rates without interrupting workflow.
  • Large backlit LCD display showing real-time battery status, selected speed mode, and directional flow indicator (aspiration/dispensing).
  • Autoclavable adapter interface (121°C, 20 min, saturated steam) compatible with standard sterile polypropylene serological pipettes (0.1–100 mL), supporting ISO 5 cleanroom and GLP-compliant aseptic techniques.
  • Integrated pressure-equalization vent with hydrophobic PTFE membrane filter to prevent internal condensation and corrosion from vaporized solvents or humidified gases.
  • Rechargeable lithium-ion battery providing up to ~2,000 pipetting cycles per charge (tested with 25 mL pipettes under standard ambient conditions); supports hot-swap operation—device remains fully functional during charging.
  • Modular base station with tool-free mounting mechanism for rapid replacement of hydrophobic membrane filters and quick disassembly for routine maintenance or decontamination.

Sample Compatibility & Compliance

The e-HC is validated for use with commercially available Class A and Class B serological pipettes conforming to ISO 8549:2020 and ASTM E535–22 specifications. It maintains accuracy and precision across a wide range of liquid classes—including aqueous buffers, protein-rich media (e.g., DMEM/F12), glycerol-containing reagents (up to 40% v/v), and ethanol-water mixtures (up to 70% v/v)—without requiring recalibration. The device meets IEC 61000-6-3 (EMC emissions) and IEC 61000-6-2 (immunity) standards. Its firmware architecture supports audit trail logging (user ID, timestamp, volume, speed mode) in alignment with FDA 21 CFR Part 11 requirements when integrated into validated LIMS or ELN environments.

Software & Data Management

While the e-HC operates as a standalone instrument, its embedded microcontroller logs operational metadata—including cycle count, cumulative runtime, and battery health metrics—for predictive maintenance scheduling. Optional firmware updates (delivered via USB-C connection) introduce enhanced calibration diagnostics and multi-user profile support. All data exports comply with CSV format for traceability integration into laboratory information management systems (LIMS) or electronic lab notebooks (ELN). No proprietary cloud platform is required; local data retention ensures compliance with institutional data sovereignty policies.

Applications

  • Cell culture maintenance: Rapid, aseptic transfer of growth media during passaging, seeding, and feeding protocols.
  • Biomanufacturing: Preparation of large-volume buffer stocks, dilution series, and harvest supernatant aliquoting in upstream processing.
  • QC/QA testing: Reproducible sample preparation for turbidity assays, endotoxin testing, and sterility validation workflows.
  • Academic research: High-fidelity liquid handling in developmental biology, organoid expansion, and 3D bioprinting support protocols.
  • Clinical diagnostics: Standardized reagent dispensing in high-volume immunoassay and molecular test preparation.

FAQ

What pipette sizes are compatible with the e-HC?
The e-HC supports all standard serological pipettes from 0.1 mL to 100 mL, including tapered and non-tapered formats meeting ISO 8549 dimensional tolerances.
Can the e-HC be used in biosafety cabinets or laminar flow hoods?
Yes—the device’s low electromagnetic emission profile and autoclavable components make it suitable for Class II A2 and B2 biosafety cabinets, provided proper airflow clearance is maintained.
Is calibration certification included with purchase?
Each unit ships with a factory-verified performance report (traceable to NIST-traceable standards); ISO/IEC 17025-accredited calibration services are available upon request.
How often should the hydrophobic membrane filter be replaced?
Under typical cell culture use, replacement is recommended every 6 months or after 500 autoclave cycles—whichever occurs first—to maintain optimal pressure balance and aerosol containment.
Does the e-HC support programmable sequences or multi-step protocols?
No—the e-HC is purpose-built for single-action aspiration/dispensing; for automated multi-step workflows, integration with third-party robotic liquid handlers via TTL trigger signals is supported through optional accessory modules.

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