Chengmengweiye CM200-1 Adjustable Nitrogen Evaporator

Overview

The Chengmengweiye CM200-1 Adjustable Nitrogen Evaporator is an engineered solution for parallel solvent removal and sample concentration in analytical laboratories. It operates on the principle of inert gas-assisted evaporation—introducing a controlled stream of nitrogen across the surface of heated liquid samples to accelerate solvent volatilization while minimizing oxidation, thermal degradation, or cross-contamination. Unlike rotary evaporation—which processes one or few samples sequentially—the CM200-1 enables simultaneous concentration of up to 12 samples under identical, reproducible thermal and gas-flow conditions. This capability significantly improves throughput in high-volume workflows such as clinical toxicology screening, pharmaceutical stability testing, environmental residue analysis (e.g., pesticide or PCB quantification), and preparative LC-MS/MS sample cleanup. The unit employs dry-block heating with aluminum alloy heating blocks for rapid thermal response and uniform heat distribution, ensuring consistent evaporation kinetics across all positions.

Key Features

• Dry-block heating system with 200 W power output, achieving temperature ramp from 40 °C to 150 °C in ≤30 minutes
• Precise digital PID temperature control with real-time LED display showing setpoint, actual block temperature, and countdown timer (up to 99 h 59 min)
• Independent flow control for each of 12 gas channels via integrated needle valves—enabling fine-tuned nitrogen delivery (0–10 L/min total) without overconsumption
• Adjustable gas manifold height and interchangeable gas needles (standard length: 150 mm), compatible with multiple tube diameters (e.g., 15 mm, 16 mm, 19 mm) via modular heating blocks (CM06, CM07, CM08, etc.)
• Integrated over-temperature protection circuitry with automatic shutdown and audible alarm upon thermal fault detection
• Compact footprint (280 × 240 × 500 mm) and ventilated chassis design—safe for operation inside fume hoods during handling of volatile or hazardous solvents (e.g., chloroform, hexane, acetonitrile)
• Uniform thermal distribution across the heating block (±0.5 °C stability at 100 °C), validated per internal calibration protocol

Sample Compatibility & Compliance

The CM200-1 accommodates standard 12-position configurations using interchangeable aluminum blocks, including CM06 (15 mm tubes), CM07 (16 mm), and CM08 (19 mm)—all dimensionally standardized to 96 × 96 × 49 mm for interchangeability. Each block features machined wells with tight thermal coupling to ensure minimal inter-well temperature deviation. While not certified to ISO/IEC 17025 or FDA 21 CFR Part 11 out-of-the-box, the instrument supports GLP/GMP-aligned workflows when operated with documented SOPs, routine temperature verification (e.g., using NIST-traceable thermometers), and maintenance logs. Its sealed dry-heating architecture eliminates water bath contamination risks and complies with laboratory biosafety requirements for non-aqueous sample processing.

Software & Data Management

The CM200-1 is a standalone hardware platform with no embedded software or network interface. All operational parameters—including temperature setpoint, run duration, and visual status indicators—are managed via front-panel controls and the dual-line LED display. For regulated environments requiring audit trails, users may integrate external data loggers (e.g., calibrated thermocouple arrays with timestamped recording) or pair the unit with LIMS-compatible environmental monitoring systems. Optional flow-regulating valves (sold separately) allow integration into centralized nitrogen supply networks with pressure regulation (<0.1 MPa max input).

Applications

• Routine concentration of extracts prior to GC-FID, GC-MS, or HPLC-UV analysis in food safety and environmental testing labs
• Preparative desolvation of plasma, urine, or tissue homogenates in clinical pharmacokinetic studies
• High-throughput sample cleanup in regulated bioanalytical labs performing USP , ICH Q2(R2), or ASTM D7066-22 compliant methods
• Removal of low-boiling solvents (e.g., dichloromethane, ethyl acetate) from derivatized steroid or vitamin D metabolites without epimerization
• Parallel evaporation in QC/QA settings where batch consistency, operator independence, and method transferability are critical

FAQ

What is the maximum recommended nitrogen inlet pressure?
The unit is rated for inlet pressure ≤0.1 MPa (1 bar). Exceeding this may compromise valve integrity or cause erratic flow behavior.
Can the CM200-1 be used with corrosive solvents such as trifluoroacetic acid (TFA)?
Only with appropriate chemical compatibility verification; standard stainless-steel gas needles and aluminum blocks are not resistant to strong acids or halogenated oxidizers. Use fluoropolymer-coated accessories and confirm material compatibility per ASTM F2616 guidelines.
Is temperature calibration traceable to national standards?
The device does not include factory-issued NIST-traceable calibration certificates. Users must perform periodic verification using accredited reference thermometers per ISO/IEC 17025 Clause 6.5.
Does the CM200-1 support programmable multi-step temperature ramps?
No—it maintains a single user-defined temperature setpoint throughout the run. Multi-stage protocols require manual intervention or external controller integration.
What safety certifications does the unit carry?
It conforms to GB 4793.1–2019 (Chinese safety standard for electrical equipment in laboratories), with CE marking for EMC and low-voltage directive compliance (self-declared). UL/ETL listing is not available.