CoMetro CP-M Series Constant Flow Pump
| Brand | CoMetro |
|---|---|
| Model | CP-M |
| Flow Rate | 10 mL/min |
| Maximum Pressure | 6000 psi |
| Accuracy | ±2% |
| Precision (RSD) | 0.2% |
| Dimensions | 175(H) × 225(W) × 305(D) mm |
| Weight | 11 kg |
| Power Supply | 230 V / 115 V, 50 / 60 Hz |
| Fluid Path Materials | PEEK or 316 Stainless Steel |
| Control Interface | Keypad and RS232 digital communication |
| Remote Input | Frequency and analog voltage |
Overview
The CoMetro CP-M Series Constant Flow Pump is an engineered solution for applications demanding stable, pulse-free liquid delivery under high-pressure conditions. Based on a precision stepper motor-driven positive displacement architecture, the CP-M utilizes a low-volume, high-efficiency accumulator-based flow conditioner combined with real-time electronic compensation to eliminate flow pulsation—critical for sensitive analytical workflows such as HPLC sample introduction, microfluidic reactor feeding, and controlled reagent dosing in catalytic synthesis. Its non-contact pressure sensing system continuously monitors backpressure without introducing mechanical hysteresis or seal wear, enabling long-term operational stability and consistent volumetric output across variable load conditions. Designed for integration into automated lab environments, the CP-M meets the fundamental requirements of ISO/IEC 17025-compliant laboratories where traceable, repeatable fluid handling is essential.
Key Features
- Pulse-free flow delivery achieved via low-inner-volume accumulator and adaptive electronic compensation algorithm
- High-pressure capability up to 6000 psi (414 bar), suitable for viscous solvent systems and packed-bed reactors
- Motor control system with closed-loop feedback ensures flow accuracy of ±2% and repeatability of ≤0.2% RSD
- Modular fluid path options: chemically inert PEEK or corrosion-resistant 316 stainless steel, compliant with USP Class VI and FDA 21 CFR Part 11 material requirements
- Integrated bypass valve and self-cleaning module reduce maintenance frequency and support GLP/GMP-aligned operational hygiene
- Dual-mode operation: local keypad control for rapid setup and RS232 serial interface for programmable integration with LIMS or SCADA systems
- Real-time monitoring of flow rate, actual pressure, upper/lower pressure limits, operational status, and fault alerts (CP-M3xx models)
Sample Compatibility & Compliance
The CP-M Series accommodates a broad range of solvents, aqueous buffers, and reactive chemical streams—including acetonitrile, THF, concentrated acids/bases, and biocompatible media—without degradation of wetted components. All PEEK and 316 SS configurations comply with ASTM F2129 for corrosion resistance and ISO 10993-5 for cytotoxicity screening. When configured with stainless steel fluid paths and operated within specified pressure and temperature ranges, the pump supports applications governed by USP , EP 3.2.1, and FDA-recommended cleaning validation protocols. The absence of dynamic seals in the pressure sensing circuit eliminates potential leachables, making it suitable for cell culture media perfusion and diagnostic assay calibration.
Software & Data Management
The CP-M Series supports ASCII-based command protocol over RS232, enabling bidirectional communication with third-party software (e.g., LabVIEW, Python-based control suites, or custom C# applications). Firmware includes timestamped event logging for pressure excursions, flow deviations, and system warnings—records are exportable in CSV format for audit trail generation. While the pump itself does not embed full 21 CFR Part 11 compliance features (e.g., electronic signatures), its deterministic behavior, hardware-enforced parameter limits, and immutable log structure facilitate qualification under GxP frameworks when deployed with validated host software and procedural controls.
Applications
- HPLC and UHPLC auxiliary pumping for column washing, gradient delay loop filling, or derivatization reagent infusion
- Controlled feed in continuous-flow chemistry reactors, including photochemical and electrochemical synthesis cells
- Calibration fluid delivery in metrology labs performing volumetric instrument verification per ISO 4064-2
- Long-duration perfusion in organ-on-chip platforms requiring stable shear stress profiles
- Teaching laboratories demonstrating fluid mechanics principles, pump efficiency curves, and pressure–flow relationships
- Environmental testing setups involving metered injection of standard solutions into ICP-MS or IC sample loops
FAQ
What is the maximum allowable viscosity for stable operation at 6000 psi?
The CP-M maintains rated accuracy up to 500 cP at full pressure; above this, flow rate deviation increases progressively due to motor torque limitations and fluid compressibility effects.
Can the CP-M be used in sterile or aseptic processes?
Yes—when equipped with PEEK fluid paths and validated cleaning-in-place (CIP) procedures, it meets ISO 13485-aligned bioprocessing requirements for non-contact fluid transfer.
Is firmware upgrade supported in-field?
Firmware updates require connection to CoMetro’s authorized service utility via RS232; no user-accessible bootloader or OTA functionality is provided.
How is flow calibration traceability established?
Factory calibration is performed using NIST-traceable gravimetric flow standards; users may perform field verification using certified micro-balance and timed-collection methodology per ISO 4064-4.
Does the pump support analog pressure feedback output?
No—pressure data is available only digitally via RS232; external analog transducers must be integrated separately if 4–20 mA or 0–10 V output is required.
