CoMetro CP-M Series High-Pressure Constant Flow Pump

Overview

The CoMetro CP-M Series High-Pressure Constant Flow Pump is an engineered solution for precision liquid delivery under demanding pressure and stability requirements. Based on positive displacement piston technology with active electronic flow compensation, the CP-M delivers pulse-free, highly reproducible flow across its operational range—critical for applications where flow integrity directly impacts analytical validity or reaction kinetics. Unlike conventional peristaltic or diaphragm pumps, the CP-M employs a motor-driven dual-piston architecture coupled with real-time pressure feedback and adaptive fill-cycle control. This architecture minimizes compressibility-induced flow deviation, particularly at elevated backpressures up to 6000 psi (413.7 bar), enabling consistent volumetric delivery in high-resistance fluidic systems such as supercritical fluid chromatography (SFC), preparative HPLC, microfluidic synthesis reactors, and high-pressure catalysis studies.

Key Features

• Ultra-stable flow output with ≤0.2% RSD (relative standard deviation) and ±2% absolute accuracy—validated per ISO 5725-2 guidelines for precision measurement systems.
• Non-contact pressure transduction system providing continuous, drift-free monitoring without mechanical wear or fluid pathway intrusion.
• Low-inner-volume pulsation-dampening accumulator integrated into the pump head assembly, reducing hydraulic inertia and improving transient response during flow ramping or gradient initiation.
• Dual-mode operation: local keypad control for benchtop flexibility and RS232 digital interface for integration into automated workflows compliant with ASTM E1384 and FDA 21 CFR Part 11 data integrity standards.
• Modular fluid path construction with chemically resistant options—316 stainless steel for broad solvent compatibility or PEEK for enhanced biocompatibility and low metal leaching in life science applications.
• Configurable safety logic including programmable upper/lower pressure limits, automatic fault-triggered bypass activation, and real-time status diagnostics (e.g., overpressure, motor stall, valve timing error).

Sample Compatibility & Compliance

The CP-M Series supports a wide range of solvents—including acetonitrile, methanol, THF, supercritical CO₂, and aqueous buffers—without degradation of flow fidelity. Its PEEK and 316 SS wetted materials meet USP Class VI biocompatibility requirements and are compatible with ISO 10993-5 cytotoxicity testing protocols. The pump’s design conforms to IEC 61010-1 for laboratory electrical safety and incorporates internal pressure relief mechanisms aligned with PED 2014/68/EU essential safety requirements. For regulated environments, firmware logging supports GLP/GMP audit trails when paired with compliant host software, and all parameter changes are timestamped and user-attributed per ALCOA+ principles.

Software & Data Management

RS232 communication enables bidirectional command exchange using ASCII-based SCPI-like syntax, supporting remote start/stop, flow rate setpoint adjustment, pressure limit configuration, and real-time telemetry streaming (flow, pressure, status flags). Optional OEM SDKs facilitate integration with LabVIEW, Python (pySerial), or custom LIMS platforms. All operational logs—including runtime hours, total delivered volume, and fault event history—are stored non-volatile memory and exportable via serial dump. When deployed in 21 CFR Part 11–regulated settings, optional digital signature modules enable electronic record authentication and role-based access control.

Applications

• Preparative and analytical-scale HPLC/SFC method development requiring stable, high-pressure mobile phase delivery.
• Microreactor and flow chemistry systems where precise stoichiometric control and residence time reproducibility are essential.
• Materials science research involving polymerization initiators, nanoparticle precursors, or catalyst slurries under elevated pressure conditions.
• Pharmaceutical QA/QC labs performing dissolution testing or forced degradation studies with controlled infusion rates.
• Academic teaching laboratories demonstrating fluid mechanics principles, pump calibration techniques, and pressure–flow relationship modeling.

FAQ

What is the maximum continuous operating pressure for the CP-M210 model?

The CP-M210 is rated for continuous operation at up to 6000 psi (413.7 bar) with appropriate fluid path material selection and thermal management.
Does the CP-M Series support gradient programming?

No—gradient generation requires external mixing or multi-pump coordination; however, the CP-M maintains stable single-solvent flow during externally imposed gradient profiles.
Can the pump be used with corrosive or high-viscosity fluids?

Yes—when equipped with 316 stainless steel or PEEK fluid paths, it handles acids, bases, and viscosities up to 500 cP at reduced flow rates, subject to pressure derating per manufacturer’s viscosity correction charts.
Is firmware update capability available?

Yes—field-upgradable firmware is distributed via secure USB-to-serial adapter and includes version-locked validation to ensure traceability in regulated environments.
How is flow calibration performed?

Calibration is conducted gravimetrically using NIST-traceable balances and certified volumetric glassware, following procedures outlined in ISO 8502-3 for volumetric metering devices.