CoMetro CP005T High-Pressure Constant-Flow Temperature-Controlled Piston Pump

Overview

The CoMetro CP005T is a high-precision, high-pressure constant-flow piston pump engineered for laboratory-scale reaction systems requiring stable, corrosion-resistant, and temperature-regulated liquid delivery. It operates on positive displacement principle using a dual-seal ceramic-coated stainless-steel plunger and precision-machined 316L stainless-steel fluid path—ensuring long-term reliability under aggressive chemical environments. Unlike peristaltic or diaphragm pumps, the CP005T delivers true volumetric flow control with minimal pulsation (<1.5% peak-to-peak), making it suitable for applications where flow stability directly impacts reaction kinetics, catalyst evaluation reproducibility, or chromatographic resolution. Its integrated Peltier-based heating/cooling module enables active temperature control of the entire fluid path from ambient +10 °C up to 120 °C—critical for viscosity-sensitive feed streams in microreactor chemistry, hydrogenation studies, or supercritical fluid-assisted synthesis.

Key Features

• High-pressure capability up to 6000 psi (414 bar), compatible with packed-bed reactors, catalytic fixed-bed evaluation units, and high-backpressure microfluidic systems
• Temperature-controlled fluid path with real-time PID regulation; thermal uniformity maintained within ±0.5 °C across full operating range
• Flow accuracy of ±2% and repeatability of 0.2% RSD over 0.001–5 mL/min range—validated per ISO 5725-2 for precision testing
• Chemically inert wetted materials: 316L stainless steel body, sapphire-hardened plungers, fluoropolymer seals resistant to halogenated solvents, strong acids, and bases
• Front-panel digital interface with simultaneous display of setpoint and actual flow rate (mL/min) and fluid temperature (°C)
• Configurable analog (0–5 V / 4–20 mA) and frequency inputs for external process synchronization; RS232 port supports ASCII command protocol for integration into LabVIEW, MATLAB, or custom SCADA environments
• Integrated bypass valve and self-cleaning cycle to prevent crystallization or polymer deposition during intermittent operation

Sample Compatibility & Compliance

The CP005T is designed for continuous, unattended delivery of low-to-medium viscosity liquids—including aqueous electrolytes, organic solvents (THF, DMF, DCM), corrosive reagents (HCl, HNO₃, HF solutions up to 10%), and thermally labile precursors. It meets mechanical safety requirements per EN 61000-6-2 (EMC immunity) and EN 61000-6-4 (EMC emission). While not certified for IEC 61010-1 Class I medical use, its construction aligns with GLP-compliant instrumentation standards for chemical process development labs. The pump supports audit-ready operation when paired with compliant data acquisition software: time-stamped flow/temperature logs, user-access-level controls, and electronic signature support conform to FDA 21 CFR Part 11 requirements when implemented with validated third-party DAQ platforms.

Software & Data Management

The CP005T does not include embedded firmware-based data logging; instead, it provides deterministic analog and digital I/O for seamless integration into existing laboratory informatics infrastructure. RS232 communication supports standard SCPI-like commands (e.g., “FLOW:SET 0.25”, “TEMP:READ?”, “STATUS?”) enabling bidirectional parameter control and status interrogation. When connected to compliant LIMS or ELN systems via OPC UA or Modbus TCP gateways, the pump contributes traceable metadata—including start/stop timestamps, flow deviation alerts (>±3% threshold), and thermal excursion flags—to raw experimental records. Optional CoMetro PumpLink™ configuration utility (Windows-based) allows offline method storage, multi-step gradient programming, and CSV export of operational history for QA/QC review.

Applications

• Microreactor feed control in continuous-flow pharmaceutical synthesis (e.g., nitration, diazotization, Grignard addition)
• Catalyst screening in fixed-bed reactors under isothermal/isobaric conditions (ASTM D3226, ISO 10723)
• Feedstock delivery for supercritical CO₂ extraction systems requiring precise co-solvent metering
• Mobile phase delivery in preparative HPLC and SFC systems where column backpressure exceeds 3000 psi
• Long-duration environmental leaching tests (EPA Method 1311, TCLP) requiring uninterrupted 72+ hour flow stability
• Calibration fluid delivery in primary flow standard laboratories adhering to ISO/IEC 17025 accreditation criteria

FAQ

What is the minimum programmable flow increment?
The CP005T supports 0.001 mL/min resolution across its full 0.001–5 mL/min range, with step response time <200 ms to 95% of target flow.
Can the pump handle slurries or particulate-laden fluids?
No—it is designed exclusively for homogeneous liquids; suspended solids >1 µm will accelerate seal wear and compromise pressure integrity.
Is remote firmware update supported?
Firmware updates require physical USB connection and CoMetro-certified service tools; no over-the-air or network-based update capability is provided.
Does the temperature control apply to the entire fluid path or only the pump head?
Heating/cooling is applied to the complete fluidic assembly—including inlet tubing manifold, plunger housing, and outlet check valve—to ensure consistent thermal state at point-of-delivery.
What validation documentation is supplied with the instrument?
Each unit ships with Factory Calibration Certificate (traceable to NIST standards), Material Compliance Declaration (RoHS/REACH), and Mechanical Safety Test Report (EN 61000 series). IQ/OQ protocols are available upon request for GMP-aligned installations.