Coolium CT4-80 Cryogenic Cold Trap Thermostat
| Brand | Coolium |
|---|---|
| Origin | Beijing, China |
| Manufacturer Type | Authorized Distributor |
| Country of Origin | China |
| Model | CT4-80 |
| Instrument Type | Horizontal |
| Temperature Stability | ≤ ±0.1 °C at –50 °C |
| Temperature Uniformity | ±0.3 °C across bath volume |
| Setpoint Resolution | 0.1 °C |
| Minimum Operating Temperature | –80 °C |
| Bath Volume | 4 L |
| External Dimensions | 360 × 600 × 300 mm (W × D × H) |
| Net Weight | 35 kg |
Overview
The Coolium CT4-80 Cryogenic Cold Trap Thermostat is an engineered solution for high-efficiency vapor condensation in vacuum-based laboratory processes. Designed around a self-contained, two-stage auto-cascade refrigeration system, it achieves stable operation down to –80 °C without liquid cryogens. Its primary function is to intercept and condense volatile vapors—such as solvents, acids, or moisture—before they reach the primary vacuum pump. This prevents oil contamination, reduces maintenance frequency, and extends pump service life. Unlike passive cold traps relying on dry ice or LN2, the CT4-80 delivers repeatable, programmable thermal performance with integrated temperature monitoring and closed-loop control. It is commonly deployed as an inline cold trap for rotary evaporators, centrifugal concentrators, freeze dryers, and vacuum distillation systems where solvent recovery, process purity, and system longevity are critical.
Key Features
- Auto-cascade refrigeration architecture enabling continuous operation at –80 °C with no external cryogen supply
- Stainless-steel cold trap chamber with electropolished interior surface; optional PTFE coating available for enhanced chemical resistance
- Horizontal configuration optimized for integration beneath rotary evaporator condensers or inline vacuum manifolds
- Precision temperature control with 0.1 °C setpoint resolution and real-time digital display
- Dedicated drain valve assembly for safe, controlled removal of condensed liquids—compatible with both aqueous and organic condensates
- Modular design supporting dual-use functionality: operates as a cold trap, low-temperature bath, pre-freezing chamber, or cryogenic sample storage vessel
- Thermally insulated housing minimizes ambient heat ingress and improves energy efficiency during extended operation
Sample Compatibility & Compliance
The CT4-80 accommodates a broad range of volatile compounds, including acetone, methanol, ethyl acetate, dichloromethane, acetonitrile, and low-boiling hydrocarbons. Its stainless-steel construction complies with general laboratory material compatibility standards for non-corrosive and mildly acidic vapors; optional fluoropolymer-coated variants meet enhanced requirements for aggressive solvents or halogenated compounds. While not certified to specific ISO or ASTM vacuum trap standards (e.g., ISO 21360-1), its operational parameters align with common practices defined in ASTM E2910 (Standard Guide for Vacuum System Performance Verification) and USP environmental control guidelines for aseptic processing support equipment. The unit supports GLP-compliant workflows when paired with validated temperature logging software and audit-trail-enabled controllers (available via optional upgrade).
Software & Data Management
The CT4-80 includes an embedded microprocessor controller with local PID tuning, ramp/soak programming, and over-temperature safety cutoff. Optional RS-485 or USB interface enables connection to third-party data acquisition platforms (e.g., LabVIEW, MATLAB, or custom SCADA systems). When integrated with Coolium’s optional PC-based monitoring suite, users gain access to time-stamped temperature logs, alarm history, and configurable export formats (CSV, PDF). All recorded data comply with ALCOA+ principles when used in regulated environments—supporting traceability, integrity, and long-term archival per FDA 21 CFR Part 11 requirements when combined with appropriate user authentication and electronic signature modules.
Applications
- Solvent trapping in rotary evaporation to improve vacuum stability and recover >95% of low-boiling fractions
- Vapor capture during lyophilization cycle development to protect primary pumps from water and excipient vapors
- Acid gas scrubbing in vacuum distillation of pharmaceutical intermediates
- Cryogenic pre-cooling of samples prior to XRD, TEM, or FTIR analysis requiring thermal stabilization
- Condensation of reaction by-products in Schlenk-line or glovebox-integrated synthesis setups
- Low-temperature calibration reference for thermocouple or RTD verification across –60 °C to –20 °C ranges
FAQ
What refrigerant does the CT4-80 use?
It employs a proprietary blend of environmentally compliant HFC/HFO refrigerants compatible with auto-cascade operation; no R22, R134a, or ozone-depleting substances are used.
Can the CT4-80 be operated continuously at –80 °C?
Yes—rated for uninterrupted operation at –80 °C under standard ambient conditions (≤25 °C, ≤60% RH); derating may apply above 30 °C ambient.
Is the bath fluid included with shipment?
No—users must select and fill with a suitable low-temperature heat transfer fluid (e.g., silicone oil rated to –90 °C or specialized cryo-fluids); Coolium provides compatibility guidance upon request.
Does the unit meet CE or UL safety certification?
It carries CCC certification for the Chinese market; CE marking is available under customer-specified conformity assessment pathways (EN 61010-1, EN 60335-1) with additional documentation and testing.
How is temperature uniformity verified across the 4 L bath volume?
Uniformity is characterized using nine-point NIST-traceable probe mapping per ICH Q5C Annex 2 methodology; typical deviation is ±0.3 °C at –50 °C steady state.
