DRETOP ZHS-150SC Temperature and Humidity Controlled Incubator
| Brand | DRETOP |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Direct Manufacturer |
| Product Category | Domestic |
| Model | ZHS-150SC |
| Heating Method | Air-Jacketed Heating |
| Cooling Method | Compressor-Based Refrigeration |
| Humidity Reservoir | External Water Tank |
| Temperature Range (with Humidification) | 15–45 °C |
| Temperature Range (without Humidification) | 10–45 °C (customizable to 0–65 °C) |
| Temperature Fluctuation | ±0.5 °C at high setpoints |
| Humidity Range | 50–95 %RH |
| Humidity Accuracy | ±3 %RH |
| Capacity | 150 L |
| Internal Dimensions (W×D×H) | 480 × 390 × 780 mm |
Overview
The DRETOP ZHS-150SC Temperature and Humidity Controlled Incubator is an engineered environmental simulation system designed for precise, long-term maintenance of temperature and relative humidity conditions in life science laboratories, pharmaceutical stability testing facilities, and industrial R&D environments. Built upon a dual-control architecture integrating microprocessor-based PID algorithms for both thermal and hygric regulation, the unit delivers stable, reproducible chamber conditions essential for ICH Q1–Q5-compliant stability studies, accelerated aging tests, microbiological culture under controlled moisture, and material performance evaluation (e.g., packaging integrity, polymer degradation, textile hygroscopic behavior). Its air-jacketed heating design ensures rapid thermal response and minimal gradient formation, while the compressor-driven refrigeration circuit—paired with eco-friendly R134a refrigerant—enables active cooling across the full operational range without reliance on external chillers or liquid nitrogen.
Key Features
- Microprocessor-controlled P.I.D. temperature and humidity regulation with 0.1 °C resolution and real-time digital display on a large backlit LCD interface;
- 30-segment programmable controller supporting time-dependent ramp/soak profiles, enabling unattended multi-phase experiments (e.g., diurnal cycling, stepwise stress protocols);
- Stainless steel interior chamber (304 grade) with fully adjustable, removable shelves; seamless corners and smooth welds facilitate ISO 14644-compliant cleaning and sterilization;
- Dual-door observation window: inner tempered glass panel with magnetic door seal and outer insulating frame to minimize thermal bridging and condensation;
- Modular refrigeration system featuring start-up delay, compressor cycle protection, and automatic recovery after power interruption;
- Four-directional casters with locking mechanism and independent leveling feet for secure positioning on uneven laboratory flooring;
- Energy-efficient axial-flow fan with optimized internal ductwork to ensure uniform air circulation and reduce localized stratification.
Sample Compatibility & Compliance
The ZHS-150SC accommodates standard Petri dishes, multi-well plates, flasks, vials, and bulk samples up to 150 L volume. Its chamber geometry and airflow dynamics support consistent environmental exposure across heterogeneous sample loads—critical for GLP-regulated stability trials per ICH Q5C and USP . The unit complies with CE marking requirements (2014/30/EU EMC Directive, 2014/35/EU LVD), meets RoHS 2011/65/EU restrictions on hazardous substances, and supports optional validation documentation packages aligned with ASTM E2500-13 (Guide for Specification, Design, and Verification of Pharmaceutical and Biopharmaceutical Manufacturing Systems). Humidity control accuracy (±3 %RH) satisfies ISO 14644-3 Class 8 cleanroom ambient monitoring prerequisites when used as a reference chamber.
Software & Data Management
Standard RS485 serial interface enables integration with LabVantage, Empower, or custom SCADA systems via Modbus RTU protocol. Optional data logging modules provide timestamped CSV export of temperature/humidity traces at user-defined intervals (1 min to 24 h), with audit trail functionality compliant with FDA 21 CFR Part 11 when paired with electronic signature-capable host software. All parameter settings—including alarm thresholds, program sequences, and calibration offsets—are stored in non-volatile memory with automatic retention during mains failure. Firmware updates are performed via USB port using DRETOP’s certified configuration utility.
Applications
- Pharmaceutical stability testing per ICH Q1A(R3) guidelines (long-term, intermediate, and accelerated conditions);
- Biological sample conditioning prior to lyophilization or freeze-drying;
- Textile and polymer hygroscopicity assessment under standardized atmospheric conditions (ASTM D5229/D5229M);
- Microbial growth studies requiring simultaneous control of thermal and moisture variables (e.g., fungal spore germination, bacterial biofilm development);
- Food product shelf-life modeling under variable RH environments (ISO 21807:2004);
- Electronics component reliability screening under high-humidity stress (JEDEC JESD22-A101).
FAQ
What is the maximum allowable ambient temperature for continuous operation?
The unit is rated for ambient temperatures between 15 °C and 30 °C. Operation above 30 °C may compromise humidity control stability and compressor duty cycle.
Can the ZHS-150SC be validated for GMP use?
Yes—DRETOP provides IQ/OQ documentation templates and supports third-party PQ execution. Calibration certificates traceable to NIST standards are available upon request.
Is remote monitoring supported out-of-the-box?
RS485 communication is standard; Ethernet or Wi-Fi connectivity requires optional gateway hardware and firmware upgrade.
How often does the external water reservoir require refilling?
Under typical 60 %RH operation at 25 °C, the 3.5 L external tank lasts approximately 72 hours. An audible low-level alert activates when capacity falls below 20 %.
Does the incubator meet noise emission limits for ISO Class 5 cleanrooms?
Measured sound pressure level is ≤52 dB(A) at 1 m distance—within acceptable limits for adjacent cleanroom support areas per ISO 14644-4 Annex B.
