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DRETOP ZHS-300SC Temperature and Humidity Controlled Incubator

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Brand DRETOP
Origin Shanghai, China
Manufacturer Type Direct Manufacturer
Product Category Domestic
Model ZHS-300SC
Heating Method Air-jacketed Heating
Cooling Method Compressor-based Refrigeration
Humidification Water Tank External Reservoir
Temperature Range (with Humidification) 15–45 °C
Temperature Range (without Humidification) 10–45 °C (customizable to 0–65 °C)
Temperature Fluctuation ±0.5 °C at high setpoints
Humidity Range 50–95 %RH
Humidity Accuracy ±3 %RH
Chamber Capacity 300 L
Internal Dimensions (W×D×H) 580×500×950 mm

Overview

The DRETOP ZHS-300SC Temperature and Humidity Controlled Incubator is an engineered environmental simulation platform designed for reproducible, long-term stability testing and biological cultivation under precisely regulated thermal and hygroscopic conditions. Based on air-jacketed heating and compressor-driven refrigeration architecture, the system maintains stable temperature and relative humidity profiles across its 300 L stainless-steel chamber—enabling compliance-critical applications in pharmaceutical stability studies (ICH Q1–Q5), microbiological growth assays, textile conditioning, food packaging shelf-life evaluation, and material aging tests. Its dual-control algorithm synchronizes independent PID loops for temperature and humidity, minimizing cross-coupling effects and ensuring traceable environmental fidelity over extended operational cycles.

Key Features

  • Air-jacketed heating system with Ni-Cr alloy heaters ensures rapid thermal response and reduced internal temperature gradients compared to direct-heating designs.
  • Compressor-based cooling circuit utilizes eco-friendly R134a refrigerant (non-ozone-depleting, GWP-compliant), integrated with programmable power modulation to sustain stable sub-ambient operation without thermal shock.
  • External humidification reservoir enables continuous water replenishment without opening the chamber—reducing contamination risk and preserving setpoint integrity during prolonged runs.
  • 30-segment programmable controller supports time-dependent ramp/soak profiles, enabling automated multi-condition testing sequences (e.g., ICH Zone IVb cycling: 30 °C/75 %RH → 40 °C/75 %RH → 50 °C/75 %RH).
  • Double-door observation window: inner tempered glass + outer magnetic door seal provides enhanced thermal insulation and visual monitoring without compromising chamber integrity.
  • Modular refrigeration unit incorporates start-delay protection, compressor cycle interval control, and automatic defrost management—extending service life and reducing maintenance frequency.
  • Stainless-steel interior (SUS304) with removable, height-adjustable shelves facilitates thorough cleaning, autoclave-compatible decontamination, and flexible load configuration.

Sample Compatibility & Compliance

The ZHS-300SC accommodates standard ISO/IEC 17025-compliant sample configurations—including Petri dishes, multi-well plates, vials, ampoules, and packaged product units—within its uniformly ventilated chamber. Internal airflow employs optimized axial fan distribution and baffle-guided laminar circulation, mitigating localized condensation and ensuring <±1.5 °C spatial uniformity (per ASTM E2876-22 verification methodology). The incubator supports GLP/GMP-aligned workflows through optional RS485 interface (Modbus RTU protocol) for integration into centralized environmental monitoring systems (EMS), and is compatible with 21 CFR Part 11-compliant data loggers when paired with external validation-grade sensors.

Software & Data Management

While the ZHS-300SC operates via embedded microprocessor control (no proprietary software required), its RS485 port enables bidirectional communication with third-party SCADA platforms or LIMS systems. Users may configure alarm thresholds (temperature/humidity deviation, sensor fault, door-open duration), assign unique device IDs, and schedule automated data export intervals. Optional accessories—including calibrated NIST-traceable temperature/humidity probes, USB data loggers with audit trail functionality, and external thermal printers—facilitate IQ/OQ documentation and regulatory submission readiness per FDA, WHO, and EU Annex 15 requirements.

Applications

  • Pharmaceutical stability testing per ICH guidelines (long-term, accelerated, intermediate conditions)
  • Microbial culture maintenance and viability assessment (e.g., ATCC strain preservation, fungal sporulation studies)
  • Textile and polymer hygrothermal aging per ISO 22196, ASTM D746, and AATCC TM147
  • Food packaging permeability and barrier performance evaluation under controlled RH gradients
  • Seed germination and plant tissue culture under defined climatic regimes
  • Electronics component reliability screening (moisture-induced failure analysis)

FAQ

What is the maximum allowable ambient temperature for reliable operation?
The unit is rated for installation in environments up to 32 °C ambient, provided adequate ventilation clearance (≥100 mm rear/side, ≥200 mm top) is maintained.
Can humidity be maintained below 50% RH?
No—the ZHS-300SC is configured for humidification only; dehumidification requires external desiccant or refrigerant-based auxiliary systems.
Is calibration certificate included with shipment?
A factory calibration report (traceable to national standards) is supplied; full ISO/IEC 17025-certified calibration requires on-site service by accredited providers.
How is temperature uniformity validated across the chamber volume?
Uniformity is verified using a 9-point thermocouple mapping protocol (per ASTM E2876), conducted during factory acceptance testing and recommended annually post-installation.
Does the incubator support remote monitoring via Ethernet or Wi-Fi?
Native Ethernet/Wi-Fi capability is not integrated; however, RS485-to-Ethernet gateways (e.g., Moxa NPort series) enable networked access when deployed within existing lab infrastructure.

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