DRETOP ZSH-1000F-II Biochemical Incubator
| Brand | DRETOP |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Direct Manufacturer |
| Country of Origin | China |
| Model | ZSH-1000F-II |
| Heating Method | Air-jacketed |
| Cooling Method | Compressor-based refrigeration |
| Air Circulation | Forced convection |
| Temperature Range | 0–70 °C |
| Temperature Accuracy | ±0.1 °C |
| Temperature Uniformity | ±1.5 °C (empty chamber, at 25 °C) |
| Temperature Fluctuation | ±0.5 °C |
| Chamber Capacity | 1000 L |
| External Dimensions (W×D×H) | 1410×890×1950 mm |
Overview
The DRETOP ZSH-1000F-II Biochemical Incubator is a high-capacity, dual-mode (heating and refrigeration) environmental control system engineered for precision temperature maintenance across life science laboratories. It operates on the principle of air-jacketed thermal regulation combined with compressor-driven active cooling—enabling stable, programmable operation from 0 °C to 70 °C without external chillers or auxiliary heating units. Designed for continuous-duty applications in BOD testing, microbial cultivation, cell-based assays, enzyme kinetics, and environmental simulation studies, this incubator meets the operational demands of ISO/IEC 17025-accredited labs, GLP-compliant quality control environments, and academic research facilities requiring long-term thermal stability under variable ambient conditions.
Key Features
- Microprocessor-based P.I.D. temperature controller with 0.1 °C resolution, real-time digital display, and adjustable alarm thresholds for over-temperature protection;
- Air-jacketed heating architecture with independent compressor refrigeration system using R134a (CFC-free) refrigerant, compliant with international environmental directives including EU F-Gas Regulation (EU No 517/2014);
- Forced-air circulation via optimized internal ducting and adjustable-speed centrifugal blower, ensuring ±1.5 °C uniformity (empty, at 25 °C) and minimizing vertical/horizontal thermal gradients;
- Stainless steel interior chamber (304 grade) with removable, height-adjustable shelves; seamless welds and rounded internal corners facilitate decontamination and autoclave-compatible cleaning protocols;
- Dual-door design with tempered glass inner door and magnetic door seal, reducing heat loss and enabling non-intrusive observation without compromising chamber integrity;
- Integrated safety systems: power-failure recovery with parameter retention, compressor start-delay and cycle-interval protection, and optional independent mechanical over-temperature cutoff;
- Modular chassis with heavy-duty casters (swivel + locking) and adjustable leveling feet for secure positioning on laboratory floors.
Sample Compatibility & Compliance
The ZSH-1000F-II accommodates standard microbiological culture vessels—including Petri dishes, flasks (up to 5 L), multi-well plates, and BOD bottles—within its 1000 L working volume. Its temperature stability profile supports ASTM D5210 (BOD5 testing), ISO 8199 (general requirements for water quality microbiology), and USP / (microbiological enumeration and testing of nonsterile products). The unit complies with IEC 61010-1:2010 for electrical safety in laboratory equipment and meets CE marking requirements for electromagnetic compatibility (EMC Directive 2014/30/EU). Optional RS485 interface enables integration into centralized lab monitoring networks adhering to FDA 21 CFR Part 11 data integrity standards when paired with validated software.
Software & Data Management
While the base model features a standalone microcontroller interface, optional upgrades include an RS485 serial port for connection to SCADA systems or LIMS platforms. When configured with the optional intelligent program controller, users may define up to 30 segmented temperature profiles with ramp/soak logic, event-triggered logging, and timestamped audit trails. All logged temperature data—including setpoints, actual readings, alarms, and power events—can be exported in CSV format for traceability and regulatory review. Firmware supports GLP/GMP-aligned features such as user access levels, electronic signatures (via external authentication), and immutable audit logs meeting ALCOA+ principles.
Applications
- Biochemical oxygen demand (BOD) analysis per Standard Methods 5210B and EPA Method 405.1;
- Microbial growth studies for food safety (ISO 4833-1), pharmaceutical water systems (USP ), and clinical diagnostics;
- Enzyme activity assays requiring precise thermal control between 4 °C and 45 °C;
- Seed germination and plant tissue culture under controlled photoperiod-independent conditions;
- Environmental stress testing of biomaterials and biodegradable polymers;
- Long-duration stability studies for reagents, antibodies, and diagnostic kits per ICH Q5C guidelines.
FAQ
What is the recommended calibration interval for the ZSH-1000F-II?
Calibration should be performed annually against NIST-traceable reference thermometers, with additional verification after relocation or major maintenance.
Can the incubator maintain 4 °C continuously?
Yes—the compressor-based cooling system sustains temperatures as low as 0 °C with ≤±0.5 °C fluctuation, making it suitable for cold-adapted organism studies and chilled storage validation.
Is the unit compatible with BOD bottle racks and standard incubator shelving?
The interior dimensions (W×D×H: 1050×590×1650 mm) accommodate industry-standard BOD rack configurations; shelf spacing is fully adjustable to accommodate stacked or suspended formats.
Does the ZSH-1000F-II support remote monitoring via Ethernet or Wi-Fi?
Native Ethernet/Wi-Fi is not included, but third-party IoT gateways can be integrated via the RS485 port using Modbus RTU protocol for cloud-based telemetry.
What documentation is provided for IQ/OQ validation?
Factory test reports, wiring diagrams, component certifications (compressor, controller, sensors), and a blank URS/IQ/OQ template are supplied with each unit to accelerate qualification in regulated environments.
