DRETOP ZSH-1500F-II Biochemical Incubator

Overview

The DRETOP ZSH-1500F-II Biochemical Incubator is a high-capacity, dual-mode (heating and refrigeration) environmental chamber engineered for precise, stable temperature control across life science and applied microbiology workflows. Designed around a robust air-jacketed heating system and a high-efficiency compressor-based cooling module, it maintains thermal stability from 0 °C to 70 °C—enabling year-round operation for BOD incubation, microbial cultivation, enzyme activity assays, cell culture pre-conditioning, and environmental simulation studies. Its forced-convection airflow architecture—optimized via integrated axial-flow fans and internal baffle-guided air channels—ensures rapid thermal equilibration and minimizes spatial gradients. The unit complies with fundamental design principles outlined in ISO 15190:2020 (laboratory safety) and supports GLP-aligned operational integrity through parameter retention, power-failure recovery, and configurable alarm thresholds.

Key Features

• Intelligent microprocessor-based P.I.D. temperature controller with 0.1 °C resolution, real-time display of setpoint, actual temperature, and elapsed time; includes over-temperature alarm with audible/visual alert and automatic cut-off.
• Double-door, dual-seal configuration: outer magnetic door gasket + inner tempered glass viewing window—enhancing thermal insulation and minimizing condensation during low-temperature operation.
• Stainless steel interior chamber (304 grade) with fully removable, height-adjustable shelves; smooth-welded corners and seamless construction facilitate sterilization and residue-free cleaning per ISO 13485 cleanroom maintenance protocols.
• Modular refrigeration system with built-in compressor protection logic—including start-up delay, stop-interval cycling, and self-diagnostic monitoring—to extend service life and ensure long-term reliability under continuous duty cycles.
• Four-directional castor wheels with independent locking feet: enables secure positioning on laboratory floors while supporting safe relocation within shared facility spaces.
• Eco-compliant refrigerant (non-ozone-depleting, low-GWP formulation) aligned with EU F-Gas Regulation (EU No 517/2014) and U.S. EPA SNAP program requirements for laboratory equipment.

Sample Compatibility & Compliance

The ZSH-1500F-II accommodates diverse sample formats—including Petri dishes, multi-well plates, Erlenmeyer flasks, serum bottles, and custom bioreactor vessels—within its 1500 L working volume. Internal dimensions (1550 × 590 × 1650 mm) support stacked or tiered rack configurations. The chamber meets essential electrical safety standards IEC 61010-1 and EMC compliance per IEC 61326-1. While not certified for medical device manufacturing under ISO 13485, its design supports audit-ready documentation practices required for FDA 21 CFR Part 11–compliant data integrity when paired with optional RS485 interface and external logging software. It is routinely deployed in laboratories adhering to ASTM D5210 (BOD testing), USP / (microbial enumeration), and EN ISO 8666 (water quality analysis).

Software & Data Management

The incubator operates as a standalone instrument with embedded firmware; no proprietary software is required for basic function. Optional accessories—including RS485 serial interface, external temperature data logger, and programmable timer modules—enable integration into centralized lab management systems (LIMS) or SCADA platforms. When configured with the optional intelligent programmable controller, users may define up to 30 segmented temperature/time profiles with ramp-hold cycles, supporting complex kinetic studies. All parameter changes are timestamped and retained post-power loss, satisfying minimum ALCOA+ data integrity criteria for traceability in regulated environments.

Applications

• Biochemical Oxygen Demand (BOD) incubation per APHA Standard Methods 5210B and ISO 5815-1.
• Microbial growth studies for QC/QA in pharmaceutical, food, and beverage production facilities.
• Environmental toxicity screening (e.g., ISO 11348-3 using *Vibrio fischeri*).
• Seed germination and plant tissue culture pre-incubation under controlled thermal regimes.
• Enzyme stability profiling across temperature gradients for industrial biocatalyst development.
• Long-term storage of temperature-sensitive reagents and reference standards where active refrigeration is required below ambient.

FAQ

What is the recommended calibration frequency for the ZSH-1500F-II?

Annual verification against NIST-traceable reference thermometers is advised; internal sensor drift should be assessed before critical BOD or regulatory submissions.
Can this incubator operate continuously at 4 °C?

Yes—its compressor system and air-jacketed design support uninterrupted operation at temperatures as low as 0 °C, provided ambient conditions remain ≤30 °C and relative humidity is <80% RH.
Is the stainless steel interior electropolished?

No—the interior uses standard 304 stainless steel with mechanical polishing; electropolishing is available as a custom-order option upon request.
Does the unit include validation documentation (IQ/OQ)?

Factory-generated OQ test reports (including uniformity mapping at 25 °C and 37 °C) are provided; IQ must be performed on-site by qualified personnel per user-defined SOPs.
What safety certifications does the ZSH-1500F-II hold?

It conforms to IEC 61010-1 (Safety Requirements for Electrical Equipment for Measurement, Control, and Laboratory Use) and CE marking requirements for EMC (EN 61326-1) and Low Voltage Directive (2014/35/EU).