DRETOP ZYL-5036R Dual-Shelf Refrigerated Orbital Incubator Shaker

Overview

The DRETOP ZYL-5036R is a dual-shelf refrigerated orbital incubator shaker engineered for precise, reproducible cultivation of microbial, cellular, and biochemical samples under tightly controlled temperature and agitation conditions. It integrates the functionality of a precision incubator and an orbital shaker into a single compact platform—enabling simultaneous thermal regulation and uniform orbital motion (26 mm orbit diameter) ideal for aerobic culture expansion, enzyme kinetics, suspension cell propagation, and small-scale bioprocess development. Unlike basic benchtop shakers, the ZYL-5036R incorporates a hermetically sealed compressor-based cooling system, allowing stable operation down to 4°C—critical for cold-adapted organism studies, protein expression at low temperatures, or preventing thermal degradation during extended assays. Its microprocessor-driven PID control architecture ensures dynamic compensation for thermal load fluctuations and mechanical inertia, delivering high fidelity in both temperature maintenance (±0.1°C) and rotational speed stability (±1 rpm), essential for GLP-compliant laboratory workflows.

Key Features

• Two independently accessible stainless-steel shelves (500 × 360 mm each), optimized for high-capacity flask loading while maintaining uniform airflow and thermal distribution across both levels.
• Brushless DC drive motor with wide-range speed modulation (0–300 rpm), zero carbon brush wear, and maintenance-free operation over >20,000 hours—ensuring long-term torque consistency and minimal vibration transmission.
• Tilt-adjustable human-centered control panel with backlit LCD interface displaying real-time temperature, speed, elapsed time, and system status—designed for intuitive navigation without requiring secondary documentation.
• Three-dimensional eccentric triple-cam drive mechanism with soft-start ramping logic, eliminating abrupt acceleration that could cause splashing, cross-contamination, or meniscus disruption in sensitive liquid cultures.
• Electrostatically coated steel exterior and electropolished 304 stainless-steel interior chamber—including shelves and door gasket—resistant to corrosion, compatible with common lab disinfectants (e.g., 70% ethanol, hydrogen peroxide vapor), and compliant with ISO 14644-1 Class 8 cleanroom handling protocols.
• Comprehensive safety suite: programmable temperature and speed limits, audible/visual deviation alarms, automatic cut-off on thermal runaway or mechanical overload, and encrypted parameter lockout to prevent unauthorized configuration changes.

Sample Compatibility & Compliance

The ZYL-5036R accommodates standard laboratory vessels including Erlenmeyer flasks (50–5000 mL), test tubes, microtiter plates (with optional adapter), and custom bioreactor bags (up to 5 L). Its dual-shelf design supports heterogeneous sample sets—e.g., parallel cultures at differing temperatures or staggered inoculation timelines—without cross-interference. The unit conforms to IEC 61010-1:2010 for electrical safety in laboratory equipment and meets EN 60335-1 requirements for refrigeration systems. Optional UV-C germicidal irradiation (254 nm) enables periodic decontamination of internal air and surfaces, supporting ISO/IEC 17025-accredited microbiology labs in maintaining sterility assurance levels (SAL) ≤10⁻⁶. All firmware operations—including data logging timestamps and parameter edits—are audit-trail enabled, satisfying FDA 21 CFR Part 11 requirements when paired with the optional USB data export module.

Software & Data Management

While the ZYL-5036R operates as a standalone instrument with embedded firmware, its optional USB data interface provides direct acquisition of time-stamped temperature, speed, and runtime logs in CSV format. This enables traceable reconstruction of experimental conditions for regulatory submissions (e.g., USP , ASTM E2500-22). No proprietary software installation is required; exported files integrate natively with Excel, LabArchives, or ELN platforms. Firmware updates are delivered via signed binary packages verified using SHA-256 checksums, ensuring integrity and version control across multi-site deployments. Parameter memory retains up to 10 user-defined protocols—including ramp rates, hold durations, and alarm thresholds—with automatic restoration post-power interruption.

Applications

• Microbial growth profiling under variable temperature-agitation regimes (e.g., E. coli expression optimization, yeast fermentation kinetics)
• Suspension mammalian cell culture (CHO, HEK293) in serum-free media requiring oxygen transfer enhancement
• Enzymatic assay development where reaction homogeneity depends on consistent orbital mixing
• Environmental microbiology studies involving psychrophilic isolates maintained at sub-ambient temperatures
• Pharmaceutical stability testing per ICH Q1A(R2) guidelines using accelerated aging protocols
• Biopolymer synthesis (e.g., alginate, chitosan) where shear-sensitive gelation must be preserved

FAQ

Does the ZYL-5036R support remote monitoring or Ethernet connectivity?
No—this model is designed for local operation only. Remote access requires integration with third-party building management systems via analog 0–10 V or 4–20 mA signal outputs (available upon request as OEM customization).
Can the two shelves operate at different temperatures?
No—the entire chamber maintains a single uniform setpoint. Dual-shelf operation refers to physical capacity, not independent thermal zones.
Is the refrigeration system suitable for continuous operation at 4°C?
Yes. The hermetic compressor and insulated double-wall construction enable uninterrupted 24/7 operation at minimum setpoint with <±0.3°C long-term drift (tested per ISO 8573-1 Annex B).
What validation documentation is provided?
Each unit ships with a Factory Acceptance Test (FAT) report including calibration certificates for temperature sensor (NIST-traceable Pt100) and tachometer (laser Doppler reference), plus mechanical vibration spectrum analysis.
Are custom shelf configurations available?
Yes—custom perforated stainless-steel trays, magnetic plate holders, or clamp-on tube racks can be fabricated to order under DRETOP’s OEM service agreement.