Elite Agress 1100 High-Performance Liquid Chromatograph
| Brand | Elite |
|---|---|
| Origin | Liaoning, China |
| Manufacturer Type | Direct Manufacturer |
| Instrument Type | Conventional HPLC System |
| Flow Rate Range | 0.001–10.000 mL/min (0.001 mL/min increment) |
| Maximum Pressure | 42 MPa |
| Autosampler Capacity | 120 positions |
| Injection Volume Range | 0–100 µL (0.1 µL increment) |
| Column Oven Temperature Range | 5 °C above ambient to 99 °C |
| UV-Vis Wavelength Range | 190–700 nm |
| Data Acquisition Frequency | 20 Hz |
Overview
The Elite Agress 1100 is a compact, cost-optimized high-performance liquid chromatograph engineered for routine analytical laboratories requiring robust separation performance without premium system complexity. Based on classical reversed-phase and normal-phase HPLC principles, the Agress 1100 employs a dual-piston reciprocating pump architecture with pulse-dampening technology to deliver stable, low-pulsation solvent delivery across its full flow range. Its modular design integrates a high-sensitivity UV-Vis absorbance detector with a fixed-pathlength flow cell, enabling quantitative analysis of organic compounds, pharmaceutical actives, natural product extracts, and environmental contaminants. The system operates under isocratic or binary gradient elution modes, supporting method development and validation workflows aligned with ISO 17025-compliant quality systems. Designed for long-term operational stability, the instrument features a monolithic chassis with reinforced mounting points and precision-machined alignment interfaces—reducing mechanical drift and improving retention time reproducibility over extended run sequences.
Key Features
- Monolithic structural frame with integrated fastening hardware enhances mechanical rigidity and minimizes vibration-induced baseline noise.
- Dual-line 2×16-character blue LCD display provides real-time monitoring of pump pressure, flow rate, detector wavelength, oven temperature, and injection status—no external PC required for basic operation.
- Front-panel self-latching power switch improves ergonomic access and reduces accidental shutdown risk during unattended runs.
- Compact footprint (W × D × H ≈ 560 × 450 × 320 mm) enables deployment in space-constrained environments including teaching labs, QC rooms, and pilot-scale R&D facilities.
- Binary gradient capability supports method scalability from screening to compliance-driven release testing, compatible with standard 4.6 mm ID analytical columns and UHPLC-compatible 2.1 mm ID formats (with appropriate fittings and dwell volume calibration).
- Column oven maintains temperature uniformity ±0.5 °C across the setpoint range, critical for retention time stability in regulated environments.
Sample Compatibility & Compliance
The Agress 1100 accommodates a broad spectrum of sample matrices—including aqueous solutions, buffered mobile phases, and moderately viscous organic solvents—within its 42 MPa pressure limit. Its 120-position autosampler supports vial-based liquid handling with programmable needle wash cycles to minimize carryover (<0.005% typical). Injection precision is maintained at ≤1.0% RSD for volumes ≥5 µL, meeting general requirements for pharmacopeial assays (USP , EP 2.2.46). While not pre-certified for 21 CFR Part 11, the system’s hardware architecture supports audit-trail-ready software upgrades; data files are generated in vendor-neutral ASCII format for third-party integration into LIMS or ELN platforms compliant with GLP/GMP documentation standards.
Software & Data Management
The Agress 1100 operates with Elite’s proprietary ChromLight software suite (v3.x), providing intuitive method setup, real-time chromatogram visualization, peak integration using tangent skim and Gaussian deconvolution algorithms, and customizable report templates. Raw data (.dat) and processed results (.xls/.pdf) are timestamped and stored locally with user-defined directory structures. Software supports export to ASTM E1381-compliant formats for inter-instrument data exchange. Optional modules include sequence scheduling, calibration curve generation with forced zero-intercept options, and multi-wavelength ratio tracking for co-elution verification.
Applications
- Pharmaceutical QC: Assay and related substances testing per ICH Q2(R2) guidelines using validated isocratic methods.
- Food safety: Detection of preservatives (e.g., benzoic acid, sorbic acid), sweeteners (aspartame, sucralose), and mycotoxins (aflatoxin B1) in fortified beverages and dairy products.
- Environmental monitoring: Quantification of PAHs and chlorinated pesticides in soil extracts following EPA Method 8330B sample preparation protocols.
- Academic research: Teaching chromatographic theory—including resolution optimization, selectivity tuning, and column efficiency calculation (N, HETP)—in undergraduate analytical chemistry curricula.
- Industrial raw material verification: Identity confirmation and purity assessment of dye intermediates, polymer additives, and agrochemical formulations.
FAQ
Is the Agress 1100 compatible with mass spectrometry detection?
No—the system is configured exclusively for UV-Vis absorbance detection and lacks the necessary interface hardware (e.g., electrospray ionization source, LC-MS transfer line) or vacuum coupling provisions.
Can the autosampler accommodate 2 mL vials?
Yes—standard tray configurations support both 1.5 mL and 2 mL screw-thread or crimp-top vials with optional adapter inserts.
What is the maximum dwell volume of the gradient system?
The system’s nominal dwell volume is 750 µL, measured according to ISO 11603:2012 Annex B using acetone step-gradient methodology.
Does the detector support variable wavelength scanning during a run?
No—it operates in fixed-wavelength mode only; spectral scanning requires external diode-array instrumentation.
Is remote monitoring supported via Ethernet or Wi-Fi?
Standard configuration includes USB 2.0 host connection only; Ethernet module is available as an optional add-on for networked lab environments.
