ESCO AC2-S Series Class II Biological Safety Cabinet
| Brand | ESCO |
|---|---|
| Origin | Singapore |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | AC2-6S1 |
| Pricing | Upon Request |
Overview
The ESCO AC2-S Series Class II Biological Safety Cabinet is an ISO 14644-1 Class 5 (ISO Class 5) laminar airflow workstation engineered for personnel, product, and environmental protection in microbiological, pharmaceutical, and clinical laboratory applications. It operates on the principle of inward airflow (for personnel protection), downward laminar flow (for product protection), and recirculated/filtered exhaust (for energy efficiency), conforming to the fundamental aerodynamic design requirements of Class II Type A2 cabinets per NSF/ANSI 49, EN 12469, and YY 0569–2011 standards. The cabinet integrates a dual ULPA filtration system, dynamic negative-pressure containment architecture, and intelligent airflow management to ensure consistent containment integrity under variable operational conditions—including filter aging, sash movement, and equipment loading.
Key Features
- Dual ULPA filters (≥99.999% efficiency at 0.12 µm) with micro-pleated, spacerless construction—providing extended service life and uniform velocity distribution across the work surface.
- Sentinel™ microprocessor-based control system with large-format, bezel-free, UV-resistant, tempered safety glass display (≥6 mm thick); supports real-time monitoring of inflow velocity, downflow velocity, filter differential pressure, and remaining filter service life.
- Dynamic™ negative-pressure containment design: a fully enclosed negative-pressure cavity surrounds all potentially contaminated positive-pressure zones—including fan chamber, filter housings, and ductwork—to prevent leakage during filter breach or seal failure.
- Ergonomic 5° sloped front sash and work surface—optimized to reduce operator fatigue during prolonged use; sash position sensor interlocks with UV lamp activation to prevent accidental exposure.
- One-piece, seamless 304 stainless steel work surface—deep-drawn in a single press operation, facilitating rapid decontamination and minimizing microbial harborage points.
- Isocide™ antimicrobial coating applied to external cabinet surfaces—inhibits bacterial colonization per ISO 22196 and JIS Z 2801 protocols without leaching or degradation over time.
- Enhanced side-wall inlet grilles with optimized geometry—suppress turbulence and reverse flow at the work area perimeter, ensuring stable laminar descent even at full sash height.
- Integrated forward airfoil and rear plenum design—enables true four-sided inward airflow envelope, maintaining consistent face velocity (0.50 ± 0.05 m/s) across the entire access opening.
Sample Compatibility & Compliance
The AC2-6S1 is validated for safe handling of Risk Group 1–2 biological agents (per WHO Laboratory Biosafety Manual, 4th ed.) and low-to-moderate toxicity chemical compounds when used with appropriate PPE and procedural controls. It meets or exceeds structural, performance, and safety requirements specified in EN 12469:2000, YY 0569–2011, and NSF/ANSI 49–2022. All units undergo independent third-party certification by accredited laboratories in Singapore and the EU. Documentation includes full test reports for airflow visualization (smoke pattern analysis), containment validation (KI-Discus® challenge testing), and filter integrity (DOP/PAO scanning). The cabinet supports GLP-compliant workflows through audit-trail-capable Sentinel™ software (optional data logging module available).
Software & Data Management
The Sentinel™ control system records operational parameters—including sash position, UV runtime, filter delta-P, and alarm history—with timestamped entries stored internally for ≥12 months. Optional USB export enables traceable data transfer for internal QA review or regulatory submission. Firmware supports secure firmware updates via encrypted USB key, aligned with IEC 62443-3-3 cybersecurity guidelines for laboratory instrumentation. No cloud connectivity is embedded; local data retention ensures compliance with institutional data sovereignty policies and GDPR/CCPA frameworks.
Applications
- Aseptic cell culture preparation and passaging in academic and biotech R&D labs.
- Preparation of sterile pharmaceuticals and compounded sterile preparations (CSPs) under USP <797> and <800> guidance.
- Molecular diagnostics workflows involving RNA/DNA extraction, PCR setup, and NGS library prep.
- Clinical microbiology procedures including pathogen isolation, susceptibility testing, and mycobacterial culture.
- Quality control testing of medical devices and raw materials where particulate and microbial contamination must be excluded.
FAQ
Does the AC2-6S1 comply with both Chinese YY 0569 and EU EN 12469 standards?
Yes—each unit carries dual-certification documentation issued by independent accredited bodies in Singapore and Germany, confirming conformance to both standards’ mechanical, airflow, and containment performance criteria.
What is the expected service life of the ULPA filters under typical lab usage?
Under standard operating conditions (8 hrs/day, 5 days/week, ambient particulate load ≤ ISO 8), the dual ULPA filters typically achieve 5–7 years of service life—monitored continuously via Sentinel™ delta-P tracking and visual lifespan estimation.
Can the cabinet be integrated into a building’s exhaust system?
Yes—the AC2-6S1 supports hard-ducted Type A2 configuration with dedicated exhaust connection (Ø150 mm), requiring minimum static pressure compensation of ±125 Pa from the facility’s exhaust fan array.
Is the Isocide™ coating registered with regulatory agencies for medical device applications?
Isocide™ is not a biocidal product under EU BPR or US EPA regulations; it is a non-leaching, polymer-bound silver-ion surface treatment certified per ISO 22196 for antibacterial activity on solid substrates—intended solely for environmental hygiene enhancement, not as a sterilant or disinfectant.
What validation documentation is provided with shipment?
Each cabinet ships with a Certificate of Conformance, full third-party test report (airflow, containment, filter integrity), calibration certificate for integrated anemometers, and a complete set of EN/YY/NSF-aligned user and maintenance manuals.
