EyeTech-Laser Laser Particle Size and Shape Analyzer by Ankersmid

Overview

The EyeTech-Laser Laser Particle Size and Shape Analyzer, developed by Ankersmid (Netherlands), implements Time-Optimized Transformation (TOT) laser imaging technology—a proprietary optical measurement principle distinct from conventional laser diffraction or static image analysis. Unlike diffraction-based systems that infer particle size from scattering patterns and require assumptions about particle morphology and refractive index, the EyeTech-Laser captures high-resolution, real-time silhouette projections of individual particles in motion. This direct imaging approach enables simultaneous quantification of both dimensional metrics (e.g., equivalent circular diameter, Feret diameters, aspect ratio, convexity) and concentration—without reliance on Mie theory or optical property inputs. Engineered for versatility across heterogeneous dispersions, it operates effectively with low- and high-concentration suspensions, translucent fibers, transparent polymers, reflective metal powders, and multi-component aerosol streams—all without dilution, calibration standards, or prior optical characterization.

Key Features

• Direct particle imaging via TOT laser shadowgraphy—no Mie theory dependency or refractive index input required
• Simultaneous acquisition of size distribution (0.1–3600 µm), shape descriptors (circularity, elongation, convexity, solidity), and volumetric concentration
• Real-time analysis of dynamic samples: liquid suspensions, dry powders on conveyor belts, aerosol plumes, and planar deposits
• No sample dilution, dispersion pretreatment, or optical compensation needed—enables native-state characterization
• Auto-focus and adaptive exposure control ensure consistent image fidelity across wide size ranges and varying opacity
• Robust mechanical architecture designed for continuous operation in QC laboratories and industrial process environments

Sample Compatibility & Compliance

The EyeTech-Laser accommodates diverse particulate systems including polydisperse polymer beads, pharmaceutical excipients, catalyst supports, mineral slurries, cellulose fibers, and metallic abrasives. Its insensitivity to optical properties allows reliable analysis of colorless glass spheres, silicone microspheres, and titanium dioxide pigments without contrast agents. The system complies with ISO 13322-2:2013 (Image Analysis for Particle Size Distribution) and supports audit-ready workflows aligned with GLP and GMP requirements. Data integrity is maintained through timestamped metadata, user-access logging, and full traceability of raw image archives—facilitating compliance with FDA 21 CFR Part 11 when integrated with validated LIMS platforms.

Software & Data Management

Ankersmid’s proprietary EyeTech Suite v5.x provides intuitive workflow navigation, batch processing, and customizable reporting templates compliant with ASTM E2918 and USP . Each measurement session stores unprocessed grayscale images, binary masks, and per-particle parameter tables in HDF5 format—ensuring full reproducibility and third-party algorithm validation. The software supports automated pass/fail criteria based on user-defined thresholds (e.g., % elongated particles > 2.5, circularity < 0.65), with export options for CSV, Excel, and PDF. Integrated database management enables longitudinal trend analysis across production lots, supplier batches, or R&D iterations—with role-based access controls and electronic signature capability for regulated environments.

Applications

• Pharmaceutical solid dosage development: monitoring granule sphericity and blend uniformity pre-compression
• Advanced ceramics manufacturing: detecting agglomerates and angular fragments in alumina and zirconia feedstocks
• Food ingredient QC: quantifying starch granule deformation during extrusion and hydration
• Environmental aerosol research: characterizing wildfire soot morphology and PM2.5/PM10 composition in real time
• Recycled polymer sorting: distinguishing PET flakes from PVC contaminants via edge sharpness and transparency profiles
• Electrode slurry optimization: correlating conductive carbon black aspect ratio with battery electrode conductivity

FAQ

Does the EyeTech-Laser require calibration with NIST-traceable standards?
No. The system employs geometric pixel-to-micron scaling verified at factory installation using certified stage micrometers; no routine recalibration is necessary.
Can it analyze particles in opaque or highly viscous media?
Yes—provided sufficient laser transmission through the medium; optional fiber-optic illumination modules extend compatibility to turbid gels and emulsions.
Is real-time online monitoring supported?
Yes, via optional inline flow cell integration (EyeTech-Flow Kit) and Ethernet/IP communication for PLC synchronization.
How is data security handled in regulated labs?
All measurement files include cryptographic hashes, digital signatures, and immutable audit trails; optional FIPS 140-2 encryption available upon request.
What maintenance intervals are recommended?
Annual optical alignment verification and quarterly cleaning of the sample chamber window using ISO Class 5 cleanroom protocols.