Great Wall R-2050EX Explosion-Proof Rotary Evaporator

Overview

The Great Wall R-2050EX Explosion-Proof Rotary Evaporator is an industrial-grade, CE-compliant purification system engineered for safe, high-throughput solvent removal under hazardous or classified environments. Designed in accordance with IEC 60079-0 and IEC 60079-1 standards for explosive atmospheres, it integrates explosion-proof motor, heating bath, electrical control cabinet, liquid-level sensor, and terminal components—each certified to Ex d II BT4 classification (Group II, Category B, T4 temperature class). Its core operation relies on vacuum-assisted thin-film evaporation: a rotating 50 L evaporation flask generates uniform film thickness under controlled thermal and rotational conditions, enabling efficient heat transfer and rapid phase separation. The system operates within a regulated temperature range of ambient +5°C to 95°C and supports continuous distillate collection without vacuum interruption—critical for GMP-aligned pharmaceutical intermediate recovery, fine chemical synthesis, and active pharmaceutical ingredient (API) purification workflows.

Key Features

• Explosion-proof architecture compliant with IEC 60079 series and ATEX Directive 2014/34/EU (Category 2G); all critical components—including drive motor, bath heater, control panel, and level switch—bear valid Ex d II BT4 certification documentation.
• Dual-stage condensation system: vertical triple-reflux condenser with main condensing area of 1.15 m² and auxiliary condenser of 0.4 m², fabricated from borosilicate glass 3.3 (DIN ISO 3585), ensuring >92% solvent recovery efficiency for low-boiling solvents such as diethyl ether, acetone, and ethyl acetate.
• Double-seal vacuum interface using PTFE + fluorinated rubber composite gaskets, achieving stable vacuum hold-down performance at ≤2 kPa/h pressure rise rate under operational load.
• Electrically actuated lift mechanism (0–170 mm stroke) with dry-run and liquid-level protection circuits; SUS304 stainless steel bath (Φ560 × 340 mm) features overtemperature cutoff and grounding fault detection.
• Quick-connect flange design (Φ125 mm standard) enables tool-free assembly/disassembly of glassware; PTFE-coated discharge valve ensures corrosion resistance against halogenated, acidic, and basic media.
• RS485 serial interface supporting MODBUS RTU protocol for integration into centralized lab automation systems or SCADA platforms—enabling remote parameter monitoring, audit trail logging, and compliance-ready data export.

Sample Compatibility & Compliance

The R-2050EX accommodates heat-sensitive organic compounds, polymer solutions, natural product extracts, and reactive intermediates across pH 1–14. Its borosilicate glass 3.3 construction resists thermal shock (ΔT ≤ 150 K) and exhibits <0.1 mm/m·K linear expansion coefficient, minimizing stress-induced fracture during rapid temperature cycling. The system meets ISO 17025 calibration traceability requirements when paired with NIST-traceable thermocouples and vacuum transducers. For regulated environments, its IP65-rated control cabinet and Ex d II BT4 certification support operation in Zone 1/21 hazardous locations per NEC Article 500 and IEC 61241. It is compatible with GLP/GMP documentation practices through optional electronic logbook integration and 21 CFR Part 11–compliant software add-ons (sold separately).

Software & Data Management

While the base unit features an integrated LCD HMI displaying real-time bath temperature, rotation speed, vacuum level, and operating status, optional firmware upgrades enable time-stamped parameter logging (≥1 Hz sampling), configurable alarm thresholds (e.g., vacuum deviation >±0.5 kPa), and CSV/Excel export via USB or RS485. Audit trails include operator ID, timestamp, parameter change history, and event codes—fully aligned with FDA 21 CFR Part 11 requirements when deployed with validated user access controls and electronic signature modules. All firmware revisions undergo regression testing per IEC 62304 Class B medical device software guidelines.

Applications

This rotary evaporator serves routine and scale-up applications in QC laboratories, pilot plants, and contract manufacturing organizations (CMOs), including: concentration of botanical extracts prior to HPLC analysis; removal of residual solvents from peptide synthesis batches; isolation of reaction products in Grignard or lithium-halogen exchange protocols; solvent exchange in nanoparticle formulation; and recovery of ethyl acetate or toluene from crystallization mother liquors. Its 50 L capacity and 24.5 L/h ethanol evaporation rate make it suitable for batch sizes ranging from 10–40 L—bridging the gap between benchtop R-1001 systems and full-scale production evaporators.

FAQ

Is the R-2050EX certified for use in Class I, Division 1 hazardous locations?

Yes—the entire electrical architecture, including motor, heater, control box, and sensors, carries Ex d II BT4 certification issued by CNEx (China National Explosion Protection Inspection Center) and is listed for Group II B gases per IEC 60079-0.
Can the system be integrated into a LIMS or MES platform?

Yes—via RS485 MODBUS RTU, it supports bi-directional communication for setpoint control, status polling, and alarm forwarding; integration requires configuration of MODBUS register mapping per the supplied protocol manual.
What maintenance intervals are recommended for vacuum seals and condenser gaskets?

PTFE-fluororubber composite seals should be inspected every 500 operational hours and replaced after 2000 hours or upon visible compression set (>15% thickness loss); condenser gasket replacement is advised annually under continuous operation.
Does the unit comply with ISO 8573-1 for compressed air quality if pneumatic accessories are added?

The base R-2050EX does not include pneumatic components; however, optional vacuum booster or automated valve kits (sold separately) conform to ISO 8573-1 Class 2:2:2 when supplied with oil-free, desiccant-dried air at 6.5 bar.
Is third-party IQ/OQ validation support available?

Yes—Great Wall provides URS templates, FAT/SAT checklists, and calibration certificates; qualified vendors offer on-site IQ/OQ execution per ASTM E2500 and Annex 15 guidelines.