Hanuo HX-3015 High-Low Temperature Circulating Chiller

Overview

The Hanuo HX-3015 High-Low Temperature Circulating Chiller is a precision-engineered thermal management system designed for laboratory-scale temperature control of external equipment and reaction vessels. Operating on a closed-loop liquid circulation principle, it maintains stable thermal conditions across a broad range of −30 °C to +100 °C using a combination of high-efficiency refrigeration and resistive heating. The unit employs a hermetically sealed, air-cooled compressor with R404A or R507 refrigerant (depending on configuration), integrated with PID-controlled electric heating elements to achieve bidirectional thermal regulation. Its dual-circulation architecture—comprising an internal bath circulation for uniform temperature distribution within the reservoir and an external pump circuit for delivering conditioned fluid to peripheral devices—enables reliable integration with spectrophotometers, viscometers, calorimeters, rotary evaporators, and jacketed reactors. Designed for continuous operation under variable load conditions, the HX-3015 meets functional requirements aligned with ISO/IEC 17025 environmental conditioning support and ASTM E2931–22 guidelines for thermal stability in analytical instrumentation.

Key Features

• Robust stainless-steel bath tank (304 grade) ensures chemical resistance, long-term durability, and compliance with hygiene standards for pharmaceutical and biotech applications.
• Microprocessor-based digital controller with real-time temperature display (0.1 °C resolution), adjustable setpoint offset correction, and programmable ramp/soak profiles.
• Dual safety architecture: compressor overheat and overcurrent protection; independent high-limit temperature cutoff with audible/visual alarm and automatic power disengagement.
• High-flow external circulation pump (16–18 L/min at low backpressure), optimized for minimal head loss when connected to external jackets or heat exchangers up to 10 m total equivalent length.
• Thermal stability of ±0.1 °C at setpoint (measured at bath sensor location per ASTM E742–21 test protocol), verified under static and dynamic load conditions.
• Compact footprint (400 × 450 × 850 mm) with rear-mounted condenser and top-access reservoir—designed for benchtop integration in space-constrained analytical labs.

Sample Compatibility & Compliance

The HX-3015 accommodates standard laboratory glassware (e.g., 1–5 L jacketed flasks, immersion coils, and flow cells) directly within its 15 L bath chamber. Compatible heat-transfer fluids include deionized water (−30 °C to 100 °C), 30% ethylene glycol/water mix (−40 °C to 90 °C), and silicone oils (up to 100 °C). All electrical components conform to IEC 61010-1:2010 safety standards for laboratory equipment. While not certified to UL or CSA as a standalone appliance, the unit’s control logic, alarm logging, and hardware interlocks support alignment with GLP and GMP documentation practices—including audit-trail readiness when paired with optional RS485/Modbus RTU interface modules. It satisfies functional prerequisites for USP thermal calibration support and ISO 17025 Clause 6.4.10 regarding environmental condition monitoring.

Software & Data Management

The HX-3015 operates via embedded firmware with no proprietary PC software dependency. Temperature setpoints, ramp rates, hold times, and deviation offsets are configured directly through the front-panel keypad and LCD. Optional analog (0–5 V / 4–20 mA) and digital (RS485 Modbus RTU) interfaces enable integration into centralized lab automation systems (e.g., LabVantage, STARLIMS, or custom SCADA). When interfaced, the device transmits real-time bath temperature, setpoint, pump status, and fault codes—supporting 21 CFR Part 11–compliant electronic record generation when deployed with validated third-party data acquisition platforms. Internal event logging captures timestamped alarms (e.g., “T > LIMIT”, “COMPRESSOR FAULT”) for post-hoc troubleshooting and quality review.

Applications

• Temperature control of UV-Vis and FTIR spectrophotometer sample compartments during kinetic studies.
• Cooling/heating of HPLC column ovens and detector flow cells to stabilize retention time and baseline noise.
• Maintaining precise thermal environments for polymer rheology testing, enzyme activity assays, and protein denaturation experiments.
• Supplying regulated coolant to rotary evaporator condensers operating below ambient dew point.
• Stabilizing laser cavity temperatures in optical spectroscopy setups requiring sub-0.2 °C thermal drift limits.
• Supporting accelerated stability testing per ICH Q1A(R3) protocols where controlled thermal cycling between −20 °C and +40 °C is required.

FAQ

What is the maximum allowable external system pressure drop the HX-3015 can overcome?
The external pump is rated for ≤1.2 bar (17 psi) differential pressure at 16 L/min flow—suitable for most jacketed reactors and coil-based heat exchangers with ≤10 m total tubing length and standard 1/4″–3/8″ ID fittings.
Can the unit operate continuously at −30 °C ambient temperature?
Yes—provided ambient humidity remains below 60% RH and ventilation clearance around the rear condenser is maintained per manufacturer specifications (≥10 cm unobstructed airflow path).
Is calibration traceability available for the internal temperature sensor?
The PT100 sensor is factory-calibrated against NIST-traceable reference standards; full calibration certificates (ISO/IEC 17025 accredited) may be obtained as a value-added service upon request.
Does the HX-3015 support remote start/stop via dry contact input?
Yes—an optional 24 VDC dry-contact interface module (part no. HX-IO-DC) enables external PLC or building management system control of power state and alarm reset.
What maintenance intervals are recommended for long-term reliability?
Compressor oil inspection every 12 months; refrigerant charge verification every 24 months; annual cleaning of condenser fins and bath interior with mild citric acid solution to prevent mineral scaling.