HTR-02 Vortex Mixer

Overview

The HTR-02 Vortex Mixer is a compact, benchtop orbital shaker engineered for reproducible sample homogenization and liquid-phase extraction in regulated laboratory environments. Unlike high-speed vortexers that rely on eccentric motion to generate turbulent mixing, the HTR-02 employs a precisely controlled, low-shear orbital rotation mechanism—optimized for gentle yet effective suspension of particulates, dissolution of powders, and phase equilibration in aqueous and organic matrices. Its operational speed range (2–40 rpm) enables method-specific tuning for sensitive applications such as immunoassay plate preparation, environmental pesticide residue extraction, and pharmaceutical dissolution profiling where excessive shear or foaming must be avoided. Designed to ISO/IEC 17025-aligned laboratory workflows, the unit integrates seamlessly into QC/QA protocols requiring traceable mixing parameters and consistent mechanical input across analytical batches.

Key Features

• Adjustable multi-angle platform (0°–90° inclination) accommodates conical tubes, centrifuge vials, microtiter plates, and custom sample containers—enabling gravity-assisted mixing for heterogeneous suspensions.
• Tool-free tube holder insertion with universal clamping geometry ensures rapid loading/unloading of up to 48 standard 12–15 mL test tubes or equivalent volume vessels without adapter reconfiguration.
• Microprocessor-controlled timer (0–99 minutes) with auto-shutoff and memory retention preserves method integrity during unattended operation; supports GLP-compliant documentation when paired with external logging systems.
• Brushless DC motor delivers stable rotational output with <±1 rpm speed accuracy across full load range, minimizing thermal drift and ensuring long-term repeatability under continuous duty cycles.
• IP20-rated enclosure with reinforced ABS housing and non-slip silicone feet provides mechanical stability on laminar flow hoods, fume cabinets, and vibration-sensitive analytical benches.

Sample Compatibility & Compliance

The HTR-02 supports a broad spectrum of container formats—including polypropylene centrifuge tubes (10–50 mL), glass scintillation vials, PCR strip tubes, and 96-well plates—without requiring proprietary accessories. Its low-torque, wide-orbit motion prevents sample splashing or cap loosening during extended mixing, making it suitable for volatile solvent-based extractions (e.g., QuEChERS workflows per AOAC 2007.01). The device complies with IEC 61010-1:2010 for electrical safety in laboratory equipment and meets EMC requirements per EN 61326-1:2013. While not certified for cleanroom use (ISO 14644), its sealed drive train and absence of lubricant migration render it compatible with Class 10,000 (ISO 7) environments when operated within enclosed workstations.

Software & Data Management

The HTR-02 operates as a standalone instrument with no embedded firmware or digital interface. All operational parameters (speed, time, angle) are set via front-panel rotary encoder and LED display—ensuring electromagnetic immunity in proximity to mass spectrometers, NMR consoles, or electrophoresis systems. For laboratories implementing 21 CFR Part 11 compliance, validated external data loggers (e.g., Omega OM-DAQPRO-5300 series) may be used to record real-time RPM and elapsed time via analog voltage output (0–5 V DC proportional to setpoint). Audit trails, user access controls, and electronic signatures must be managed at the laboratory information management system (LIMS) level, as the mixer itself does not store or transmit operational history.

Applications

• Food safety testing: Homogenization of composite food samples prior to mycotoxin or heavy metal analysis (AOAC 999.08, ISO 17072-1).
• Agricultural residue monitoring: Extraction of organophosphate pesticides from leafy produce using acetonitrile/water partitioning (EN 15662:2018).
• Clinical diagnostics: Reconstitution of lyophilized calibrators and controls in immunology assays (CLSI EP26-A).
• Environmental analysis: Slurry mixing of sediment cores for PAH and PCB quantification (EPA Method 8270D).
• Pharmaceutical R&D: Wet granulation endpoint detection in small-batch formulation studies.

FAQ

Is the HTR-02 suitable for mixing viscous solutions such as glycerol-water mixtures?

Yes—the orbital motion profile maintains torque consistency up to 10,000 cP viscosity at 20 rpm; however, optimal dispersion requires pre-wetting of solids and incremental speed ramping.
Can the unit be mounted in an incubator or cold room?

It is rated for ambient operation between 5–40°C and 20–80% RH non-condensing; prolonged exposure below 10°C may affect encoder responsiveness and motor startup torque.
Does the HTR-02 support GMP documentation requirements?

While the device lacks built-in audit trail functionality, its mechanical simplicity, fixed calibration points, and compatibility with third-party validation kits enable IQ/OQ/PQ execution per ASTM E2500-13 guidelines.
What tube sizes are natively supported without adapters?

Standard configurations accommodate 12–15 mL round-bottom and conical tubes (diameter 14–17 mm); 1.5 mL microcentrifuge tubes require optional spring-loaded inserts (sold separately).
Is service calibration available outside mainland China?

Calibration certificates traceable to NIM (National Institute of Metrology, China) are provided with each unit; international recalibration services are coordinated through authorized regional distributors under ISO/IEC 17025-accredited labs.